Results 51 to 60 of about 54,391 (157)

Manifestations of Familial Hemiplegic Migraine

Pediatric Neurology Briefs, 2012
Researchers at University of Arkansas, Little Rock, AR report 3 cases of familial hemiplegic migraine complicated by reversible cerebral edema and followed by neurocognitive impairment.
J Gordon Millichap
doaj   +1 more source

A novel mutation in the ATP1A2 gene associated with a sporadic hemiplegic migraine and multiple supraventricular arrhythmias: A case report

Cephalalgia Reports
Introduction ATP1A2 mutations are identified as a genetic cause of type 2 hemiplegic migraine, but to date, no ATP1A2 gene variant has been linked to heart rhythm disorders Case presentation A 37-year-old woman presented with sporadic hemiplegic migraine
Sarvnaz Shalchian Tehran, Pierre Maquet
doaj   +1 more source

Clinical characterization of a novel ATP1A2 p.Gly615Glu mutation in nine family members with familial hemiplegic migraine. [PDF]

Brain Commun
Familial hemiplegic migraine type 2 results from pathogenic variants in the ATP1A2 gene, which encodes for a catalytic subunit of sodium/potassium ATPase.
Romozzi M, Spartano S, L'Erario FF, Iannone LF, Trigila V, Gentile A, Sanginario P, Calabresi P, Tiziano FD, Vollono C.   +9 more
europepmc   +2 more sources

Epilepsy: Molecular Pathogenesis and Emerging Therapies

MedComm, Volume 7, Issue 4, April 2026.
Progress has been made in the molecular pathogenesis of epilepsy, revealing multiple therapeutic targets. Recent advances in pharmacology, materials science, and surgical technique, coupled with progress in targeted therapy and disruptive epilepsy network technology, have led to the emergence of innovative strategies for epilepsy treatment.
Wanbin Huang, Jiabin Zong, Yu Zhang, Ming Li, Songqing Pan, Zheman Xiao   +5 more
wiley   +1 more source

Trigeminal neuralgia, migraine and sympathetic hyperactivity in a patient with Parry–Romberg syndrome [PDF]

, 2006
Parry–Romberg syndrome is a rare disorder of unknown aetiology that involves slowly progressive but self-limited wasting of subcutaneous tissues on one side of the face, usually in the distribution of a branch of the trigeminal nerve.
Drummond, P.D., Finch, P.M., Hassard, S.
core  

Retrospective analysis of the tolerability and effectiveness of rimegepant for the acute treatment of migraine in adolescents

Headache: The Journal of Head and Face Pain, Volume 66, Issue 4, Page 829-834, April 2026.
Abstract Objective This study aims to evaluate the tolerability and effectiveness of the off‐label use of rimegepant as acute migraine treatment in adolescents. Background Calcitonin gene‐related peptide (CGRP) levels are elevated during migraine attacks.
Konstantinos Tourlas, Sruthi Ilangovan, Chelsea White, Samantha L. Irwin, Sara Pavitt   +4 more
wiley   +1 more source

Efficacy and safety of rimegepant for the acute treatment of migraine in Black or African American adults: A post hoc pooled subgroup analysis from three randomized, placebo‐controlled clinical trials

Headache: The Journal of Head and Face Pain, Volume 66, Issue 4, Page 874-884, April 2026.
Abstract Objective This post hoc subgroup analysis was conducted using pooled data from three US‐based clinical trials to compare efficacy and safety of rimegepant 75 mg versus placebo in acute migraine in adults who are Black or African American.
Larry Charleston IV, Cynthia E. Armand, Teshamae S. Monteith, Hope L. O'Brien, Chandra C. Abbott, Glenn C. Pixton, Terence Fullerton   +6 more
wiley   +1 more source

The contribution of CACNA1A, ATP1A2 and SCN1A mutations in hemiplegic migraine : A clinical and genetic study in Finnish migraine families [PDF]

, 2018
Objective To study the position of hemiplegic migraine in the clinical spectrum of migraine with aura and to reveal the importance of CACNA1A, ATP1A2 and SCN1A in the development of hemiplegic migraine in Finnish migraine families.
Ilmavirta, Matti, Keski-Säntti, Petra, Marja-Liisa Sumelahti, Gormley, Padhraig, Marjo Eveliina Hiekkala, Häppölä, Elisa, Hanna Harno, Havanka, Hannele, Wessman, Maija, Matti Ilmavirta, Vuola, Pietari, Färkkilä, Markus, Elisa Häppölä, Markus Färkkilä, Harno, Hanna, Pietari Vuola, Erkki Säkö, Vepsäläinen, Salli, Padhraig Gormley, Ville Artto, Salli Vepsäläinen, Paavo Häppölä, Hämäläinen, Eija, Dennis Lal, Aarno Palotie, Sumelahti, Marja-Liisa, Lal, Dennis, Kallela, Mikko, Mikko Kallela, Palotie, Aarno, Eija Hämäläinen, Nissilä, Markku, Markku Nissilä, Säkö, Erkki, Hannele Havanka, Cuenca-Leon, Ester, Kaunisto, Mari Anneli, Ester Cuenca-León, Artto, Ville, Mari Anneli Kaunisto, Häppölä, Paavo, Petra Keski-Säntti, Maija Wessman, Hiekkala, Marjo Eveliina   +43 more
core   +1 more source

Spreading depolarization and its influence on epileptiform activity

Epilepsia, Volume 67, Issue 3, Page 1078-1089, March 2026.
Abstract Spreading depolarization (SD) is a transient disruption of electrographic activity that slowly propagates through the gray matter by chemical contiguity, and it is characterized by a large depolarization of neurons and glial cells. SD, which is associated with massive changes in ion homeostasis, including extreme increases in [K+]o, was shown ...
Maxime Lévesque, Rüdiger Köhling, Massimo Avoli   +2 more
wiley   +1 more source

Comprehensive assessment of erenumab efficacy in participants with high‐frequency episodic migraine with at least one previously failed preventive treatment: The EMBRACE study

Headache: The Journal of Head and Face Pain, Volume 66, Issue 3, Page 658-671, March 2026.
Abstract Objective To evaluate the effect of erenumab treatment beyond monthly migraine days in patients with high‐frequency episodic migraine who did not respond to at least one previous migraine preventive treatment. Background Reduction in monthly migraine days has been the efficacy standard for migraine preventive treatments; however, it does not ...
Gabriel Paiva da Silva Lima, Renata Rao, Gyöngyi Szabó, Sebastian Szklener, Cristina Tassorelli, Marcin Nastaj, Denise E. Chou, Ani C. Khodavirdi, Mahan Chehrenama, Yineng Zhu, Ajay K. Bhatia, David W. Dodick   +11 more
wiley   +1 more source