Cardiotoxic and Arrhythmogenic Effects of Hemiscorpius lepturus Scorpion Venom in Rats [PDF]
Journal of Arthropod-Borne Diseases, 2015 Background: Envenomation by Hemiscorpius lepturus is not painful and the clinical manifestations include bloody urine due to hemoglobinuria or hematuria, dermonecrotic reactions,cardiac arrhythmia and in minority of cases acute renal failure which may ...
Khalil Pourkhalili +7 more
doaj +8 more sources
Serological, pathological and scintigraphic assessment of Hemiscorpius lepturus effects on renal dysfunction in rats [PDF]
Iranian Journal of Basic Medical Sciences, 2018 Objective(s): Hemiscorpius lepturus is one of the dangerous scorpions of Iran leading to acute kidney injury (AKI) especially in infants. The purpose of this animal study was to compare the serological, pathological and scintigraphic data to quickly ...
Ali Movahed +7 more
doaj +6 more sources
Discovery of Leptulipin, a New Anticancer Protein from theIranian Scorpion, Hemiscorpius lepturus [PDF]
Molecules, 2022 Cancer is one of the leading causes of mortality in the world. Unfortunately, the present anticancer chemotherapeutics display high cytotoxicity. Accordingly, the discovery of new anticancer agents with lower side effects is highly necessitated.
Ali Rezaei +10 more
doaj +5 more sources
Discovery of a New Analgesic Peptide, Leptucin, from the Iranian Scorpion, Hemiscorpius lepturus [PDF]
Molecules, 2021 Hemiscorpius lepturus scorpion stings do not induce considerable pain based on epidemiological surveys conducted in the southwest part of Iran. Accordingly, this study was aimed to identify the analgesic molecule in H.
Sedigheh Bagheri-Ziari +4 more
doaj +5 more sources
Cellular Immunity in Mice Vaccinated with Recombinant Phospholipase D Toxoid of Hemiscorpius lepturus Scorpion [PDF]
Journal of Arthropod-Borne Diseases, 2022 Background: Hemiscorpius lepturus is one of the most dangerous scorpions in Iran and the world. Numerous studies have been conducted on phospholipases, especially phospholipase D, in this scorpion’s venom, and the results have shown this protein to be ...
Narges Safari-Foroushani +4 more
doaj +4 more sources
Inhibitory Effect of Hemiscorpius lepturus Scorpion Venom Fractions on Tachyzoites of Toxoplasma gondii [PDF]
Iranian Journal of Parasitology, 2022 Background: The present study determined the effect of the fractions obtained from Hemiscorpius lepturus scorpion venom on the tachyzoite of Toxoplasma gondii. Methods: The fractions of dried venom of He.
Lida Khaleghi Rostamkolaie +5 more
doaj +4 more sources
A biodistribution study of Hemiscorpius lepturus scorpion venom and available polyclonal antivenom in rats [PDF]
Journal of Venomous Animals and Toxins including Tropical Diseases, 2012 The purpose of the present study was to investigate the biodistribution profile of the venom of Hemiscorpius lepturus, the most dangerous scorpion in Iran.
R Seyedian +4 more
doaj +7 more sources
A comparative study on the equine and camelid antivenoms upon cardiovascular changes induced with Hemiscorpius lepturus venom in rats [PDF]
Iranian Journal of Basic Medical Sciences, 2019 Objective(s): In this study, the neutralizing abilities of the equine and the recently introduced camelid antivenoms on the hemodynamic parameters (inotropism, chronotropism, and arrhythmogenicity) were assessed following envenomation by Hemiscorpius ...
Hossein Fatemikia +8 more
doaj +5 more sources
Purification and characterization of a novel type of neurotoxic peptides from the venom of the Iranian scorpion Hemiscorpius lepturus [PDF]
Iranian Journal of Basic Medical Sciences, 2020 Objective(s): Scorpion venom has toxic effects on mammals, insects and crustaceans. Toxicogenic peptides are major contributors to the scorpion venom, which make it toxic. The Hemiscorpius lepturus (H.
Mahboob Maleki +1 more
doaj +2 more sources
Novel Mutant Phospholipase D from Hemiscorpius lepturus Acts as A Highly Immunogen in BALB/c Mice Against the Lethality of Scorpion Venom [PDF]
Molecules, 2020 Hemiscorpius lepturus (H. lepturus) which belongs to the Scorpionidae family, is the deadliest scorpion in Iran. It causes pathological manifestations like dermonecrosis, hemolysis, renal failure, necrotic ulcers, and in some cases, even death. The venom
Abouzar Soleimani Moez +4 more
doaj +2 more sources