Results 81 to 90 of about 37,295 (215)

Hereditary hemochromatosis: pathogenesis, symptoms, diagnosis and current treatment - literature review

Journal of Education, Health and Sport
Introduction: Hereditary hemochromatosis is the most common genetic disorder in Northern Europe. It involves an overload of iron in the tissues due to a deficiency of the protein hepcidin.
Dominika Prystacka-Szar, Natalia Rulewska, Filip Grabowski, Jakub Siemko, Dagmara Neska , Justyna Stadler-Szajda, Adrianna Czyżnikiewicz, Wenancjusz Stołowski, Magdalena Bujak, Magdalena Waśniowska   +9 more
doaj   +1 more source

Should the Children of Patients with Hemochromatosis be Screened for the Disease?

Canadian Journal of Gastroenterology, 1988
Idiopathic hemochromatosis is an underdiagnosed treatable condition inherited in an autosomal recessive pattern. Since early treatment is of demonstrated value, screening of high risk groups of individuals in a valuable exercise in preventive medicine ...
Donald G. MacIntosh, John C. Bear, John Simpson, Terry A. Komusi, William H. Marshall, James A. Barrowman   +5 more
doaj   +1 more source

Pituitary hyposignal characteristic of hemochromatosis on MRI

Clinical Case Reports, 2023
Pituitary haemochromatosis is an endocrine disorder caused by the accumulation of iron due to a lack of absorption during haemochromatosis. The characteristic appearance on MRI is a T2 and T2* hyposignal of the anterior pituitary gland without ...
Romeo Thierry Yehouenou Tessi, Rita Koudouhonon Oze, Mustapha Outznit, Ihssan Hadj Hsain, Ittimade Nassar, Nabil Moatassim Billah   +5 more
doaj   +1 more source

Pathological significance of intranuclear structures in liver biopsy samples

Hepatology Research, EarlyView.
Schematic representation of the potential significance of three distinct nuclear structures. Glycogenated nuclei reflects excessive glycogen accumulation in the hepatocytes. Nucleoplasmic lipid droplets form in the nucleus during hepatocyte injury. Cytoplasmic lipid droplets in the nucleoplasmic reticulum are suppressed when there is excessive fat ...
Norihiro Imai, Yuki Ohsaki, Jinglei Cheng, Hanna Kawecka, Jingjing Zhang, Fumitaka Mizuno, Taku Tanaka, Shinya Yokoyama, Kenta Yamamoto, Takanori Ito, Yoji Ishizu, Takashi Honda, Tetsuya Ishikawa, Michał Woźniak, Hiroaki Wake, Hiroki Kawashima   +15 more
wiley   +1 more source

Eligibility and Exclusion of Hemochromatosis Patients as Voluntary Blood Donors

Canadian Journal of Gastroenterology, 1998
BACKGROUND: Hereditary hemochromatosis patients are excluded in many countries as voluntary blood donors. In 1991, changes in the Canadian Red Cross policy allowed healthy hemochromatosis patients to become voluntary donors.
M Levstik, PC Adams
doaj   +1 more source

Genetic analysis of the correlation between GLP1 action and metabolic liver disease: Insights from Mendelian randomization analysis

Journal of Diabetes Investigation, EarlyView.
Our study provides genetic analysis supporting the beneficial effects of GLP1 action on MASLD. These benefits may be attributed to mechanisms such as lowering blood glucose levels, reducing blood pressure, and improving HDL cholesterol levels. ABSTRACT Purpose Previous studies have shown that glucagon‐like peptide 1 (GLP1) receptor agonists may help ...
Zhiqiang Ma, Binyu Wang, Danpei Li, Xi Chen   +3 more
wiley   +1 more source

Dermatologic manifestations of hereditary hemochromatosis: A systematic review

Journal of the European Academy of Dermatology and Venereology, Volume 39, Issue 5, Page 976-986, May 2025.
Abstract Hereditary hemochromatosis (HH) is a genetic disorder leading to excessive iron absorption, impacting multiple organs, notably the skin, nails and mucosae. The objective of this study is to elucidate the dermatologic manifestations, associated symptoms, pathophysiology and management recommendations of HH.
Hossein Akbarialiabad, Parnian Jamshidi, Jeffrey P. Callen, Dédée F. Murrell   +3 more
wiley   +1 more source

Weaning of immunosuppression in long - Term liver transplant recipients [PDF]

, 1995
Seventy-two long-surviving liver transplant recipients were evaluated prospectively, including a baseline allograft biopsy for weaning off of immunosuppression.
Abu-Elmagd, K, Demetris, AJ, Ebert, F, Flynn, B, Fung, JJ, McMichael, J, Ramos, H, Reinsmoen, N, Reyes, J, Starzl, TE, Tzakis, A, Zeevi, A   +11 more
core   +1 more source

Dysmetabolic Hyperferritinemia: All Iron Overload Is Not Hemochromatosis

Case Reports in Gastroenterology, 2015
Disturbances in iron metabolism can be genetic or acquired and accordingly manifest as primary or secondary iron overload state. Organ damage may result from iron overload and manifest clinically as cirrhosis, diabetes mellitus, arthritis, endocrine ...
Jasbir Makker, Ahmad Hanif, Bharat Bajantri, Sridhar Chilimuri   +3 more
doaj   +1 more source

Feasibility of conducting a randomized controlled trial to explore the muscular influence of post‐operative intravenous iron treatment for anaemia after major abdominal surgery

Vox Sanguinis, EarlyView.
Abstract Background and Objectives Iron deficiency anaemia is common in patients recovering from major surgery and is associated with poorer post‐operative outcomes. We designed a randomized controlled trial treating post‐operative anaemia with iron therapy to observe the influence on post‐operative recovery.
Beth MacLean, Robert U. Newton, Jayne Lim, Toby Richards   +3 more
wiley   +1 more source