Results 21 to 30 of about 1,731 (177)
Antitumor Properties of Epitope-Specific Engineered Vaccine in Murine Model of Melanoma
Marine Drugs, 2022 Finding new effective compounds of natural origin for composing anti-tumor vaccines is one of the main goals of antitumor research. Promising anti-cancer agents are the gastropodan hemocyanins–multimeric copper-containing glycoproteins used so far for ...
Emiliya Stoyanova +8 more
doaj +1 more source
A novel immunomodulatory hemocyanin from the limpet Fissurella latimarginata promotes potent anti-tumor activity in melanoma. [PDF]
PLoS ONE, 2014 Hemocyanins, the huge oxygen-transporting glycoproteins of some mollusks, are used as immunomodulatory proteins with proven anti-cancer properties. The biodiversity of hemocyanins has promoted interest in identifying new anti-cancer candidates with ...
Sergio Arancibia +12 more
doaj +1 more source
The occurrence of hemocyanin in Hexapoda [PDF]
The FEBS Journal, 2009 Hemocyanins are copper‐containing, respiratory proteins that have been thoroughly studied in various arthropod subphyla. Specific O2‐transport proteins have long been considered unnecessary in Hexapoda (including Insecta), which acquire O2 via an elaborate tracheal system.
Christian, Pick +2 more
openaire +2 more sources
Frontiers in Immunology, 2019 Mollusk hemocyanins have biomedical uses as carriers/adjuvants and nonspecific immunostimulants with beneficial clinical outcomes by triggering the production of proinflammatory cytokines in antigen-presenting cells (APCs) and driving immune responses ...
José M. Jiménez +13 more
doaj +1 more source
Jumping on the Edge—First Evidence for a 2 × 6-meric Hemocyanin in Springtails
Biomolecules, 2019 Hemocyanins are respiratory dioxygen carrier proteins found in many arthropods including ancient terrestrial species such as spiders and scorpions as well as marine horseshoe crabs.
Juliane Schmidt +2 more
doaj +1 more source
Crystallization and preliminary analysis of crystals of the 24-meric hemocyanin of the emperor scorpion (Pandinus imperator). [PDF]
PLoS ONE, 2012 Hemocyanins are giant oxygen transport proteins found in the hemolymph of several invertebrate phyla. They constitute giant multimeric molecules whose size range up to that of cell organelles such as ribosomes or even small viruses.
Elmar Jaenicke +3 more
doaj +1 more source
The Oxidation of Hemocyanin [PDF]
European Journal of Biochemistry, 1995 The reaction that gives met‐hemocyanin from Octopus vulgaris oxy‐hemocyanin has been reinvesti‐gated under several experimental conditions. Various anions including azide, fluoride and acetate have been found to promote this reaction. Kinetic data indicate that the reaction mechanism is different from that currently accepted involving a peroxide ...
BELTRAMINI, MARIANO +5 more
openaire +3 more sources
PLoS ONE, 2020 Structural knowledge of gastropod hemocyanins is scarce. To better understand their evolution and diversity we studied the hemocyanin of a caenogastropod, Pomacea canaliculata (PcH).
Ignacio Rafael Chiumiento +5 more
doaj +1 more source
Extraordinary stability of hemocyanins from L. polyphemus and E. californicum studied using infrared spectroscopy from 294 to 20 K [PDF]
, 2016 Hemocyanins are large oligomeric respiratory proteins found in many arthropods and molluscs. Here we give infrared spectroscopic evidence of a high stability towards exposure to sub-zero temperatures for hemocyanins from the arthropods Limulus polyphemus
Khalil, M. (Mireille) +3 more
core +1 more source
Spectroscopic studies on the oxygen-binding site of hemocyanins. [PDF]
, 1977 Hemocyanins are multisubunit proteins which occur freely dissolved in the hemolymph of many molluscs (such as snails and squids) and arthropods (such as crabs, lohsters, spiders and scorpions).
Deen, Hendrik van der, +1 more
core +6 more sources