Results 101 to 110 of about 46,727 (267)

ELEVATED MEAN CELL VOLUME IN SICKLE CELL ANAEMIA: ONE STORY, TOO MANY? [PDF]

Sanamed
Introduction: Sickle cell disease is a hereditary blood disorder characterized by defective hemoglobin. Red cell indices are proposed as potential tools for diagnosing and managing sickle cell disorders.
Jeremiah Zaccheaus, Alee Magnus
doaj   +1 more source

Evaluation of surgical evacuation of the uterus for abortion and management of miscarriage in patients with sickle cell disease: A multicentre UK study

British Journal of Haematology, EarlyView.
Sonia Wolf, Natasha Lewis, Funmi Oyesanya, Karlene Birthwright, Tracey Masters, Andriana Andreeva   +5 more
wiley   +1 more source

Academic and cerebrovascular outcomes after neurodevelopmental screening in sickle cell disease: A longitudinal cohort study

Developmental Medicine &Child Neurology, EarlyView.
Neurodevelopmental screening in toddlers or preschoolers with sickle cell disease (SCD) predicts future academic deficits. Screening sensitivity for future academic deficits is highest in preschoolers with SCD. Brief neurodevelopmental screening tools can identify high risk children for early intervention. Abstract Aim To assess the predictive validity
Sarah E. Bills, Jeffrey Schatz, Elizabeth Gillooly, Julia D. Johnston, A. Lauren Waters, Alyssa M. Schlenz   +5 more
wiley   +1 more source

Differential complement activation by alloantibodies in sickle cell hyperhaemolysis syndrome may influence disease course

British Journal of Haematology, EarlyView.
Mamie M. Thant, Jahnavi Gollamudi, Stefanie W. Benoit, Satheesh Chonat, Jose A. Cancelas   +4 more
wiley   +1 more source

Patient‐Reported Outcomes With Luspatercept Through 5 Years of Treatment in Patients With Non‐Transfusion‐Dependent β‐Thalassemia Treated in the BEYOND Trial

European Journal of Haematology, EarlyView.
ABSTRACT In the phase 2, double‐blind, randomized controlled BEYOND trial (NCT03342404), luspatercept increased hemoglobin levels in patients with non‐transfusion‐dependent β‐thalassemia (NTDT). This study assessed long‐term effects of luspatercept on patient‐reported outcomes (PROs), using data from BEYOND and patients who continued luspatercept ...
Khaled M. Musallam, Maria Domenica Cappellini, Antonis Kattamis, Matthew Dyer, Ahmed Hnoosh, Laurie Eliason, Christopher G. Pelligra, Shien Guo, Yutian Mu, Loyse Felber Medlin, Marta Reverte, Kevin H. M. Kuo, Ali T. Taher   +12 more
wiley   +1 more source

Sequential gastric and ileal perforations, a rare presentation in a man with sickle cell anemia: A case report

Journal of International Medical Research
The inheritance of the sickle gene (hemoglobin S) and another abnormal hemoglobin gene is described as sickle cell disease, and the homozygous form of the disease is hemoglobin SS.
John A Ashindoitiang, Victor IC Nwagbara, Dino N Magam, Victor D Nnalue, Maurice E Asuquo   +4 more
doaj   +1 more source

Human induced pluripotent stem cells can reach complete terminal maturation: in vivo and in vitro evidence in the erythropoietic differentiation model

Haematologica, 2012
Background Human induced pluripotent stem cells offer perspectives for cell therapy and research models for diseases. We applied this approach to the normal and pathological erythroid differentiation model by establishing induced pluripotent stem cells ...
Ladan Kobari, Frank Yates, Noufissa Oudrhiri, Alain Francina, Laurent Kiger, Christelle Mazurier, Shaghayegh Rouzbeh, Wassim El-Nemer, Nicolas Hebert, Marie-Catherine Giarratana, Sabine François, Alain Chapel, Hélène Lapillonne, Dominique Luton, Annelise Bennaceur-Griscelli, Luc Douay   +15 more
doaj   +1 more source

Inherited hemolytic disorders with high occurrence of b-thalassemia in Sindhi community of Jabalpur town in Madhya Pradesh, India [PDF]

, 2010
Hereditary hemolytic disorders such as hemoglobin disorders, β-thalassemia syndrome, G6PD deficiency, and ABO and Rhesus blood groups are the most common public health problems in India.
Balgir, RS
core   +1 more source

Gene Editing for Haemophilia—The Next Frontier

Haemophilia, EarlyView.
ABSTRACT The recently approved haemophilia A and B gene therapies via adeno‐associated virus (AAV) showed a promising therapeutic response after a single injection, but there are still limitations, including the potential loss of transgene expression and restriction in adults.
Mirko Pinotti, Gregory A. Newby, Sundar Selvaraj, Steven W. Pipe   +3 more
wiley   +1 more source

Hair‐on‐end sign in severe sickle cell disease

British Journal of Haematology, EarlyView.
Raquel da Costa Neves, Joana Pais de Faria, Paula Kjöllerström   +2 more
wiley   +1 more source