Results 111 to 120 of about 29,542 (277)

Human induced pluripotent stem cells can reach complete terminal maturation: in vivo and in vitro evidence in the erythropoietic differentiation model

Haematologica, 2012
Background Human induced pluripotent stem cells offer perspectives for cell therapy and research models for diseases. We applied this approach to the normal and pathological erythroid differentiation model by establishing induced pluripotent stem cells ...
Ladan Kobari, Frank Yates, Noufissa Oudrhiri, Alain Francina, Laurent Kiger, Christelle Mazurier, Shaghayegh Rouzbeh, Wassim El-Nemer, Nicolas Hebert, Marie-Catherine Giarratana, Sabine François, Alain Chapel, Hélène Lapillonne, Dominique Luton, Annelise Bennaceur-Griscelli, Luc Douay   +15 more
doaj   +1 more source

Get screened for sickle cell trait [PDF]

Know Your StatusDid you know there\u2019s more than one way to inherit Sickle Cell Disease?If you don\u2019t have a health care provider, visit our Sickle Cell Disease National Resource Directory at www.cdc.gov/ncbddd/sicklecellSickle Cell Disease ...

core  

The Sickling Phenomenon and Heterogeneity of Deer Hemoglobin.

Experimental Biology and Medicine, 1964
SummaryA marked degree of heterogeneity is demonstrable in deer hemoglobin. This heterogeneity appears to be on a genetic basis. A single hemoglobin component responsible for sickling of deer hemoglobin can be identified.Addendum. Since this paper was prepared, similar electrophoretic results were reported by Kitchen, H., Putnam, F. W. and Taylor, W. J.
openaire   +2 more sources

Acute pain transfusion reaction in a patient with thalassemia: In‐depth characterization of short‐ and long‐term phenotypes

Transfusion, EarlyView.
Abstract Background Acute pain transfusion reaction (APTR) is a rare, under‐recognized condition of unknown etiology. It can cause significant distress in recipients, necessitating symptomatic management and, occasionally, hospitalization. Study Design and Methods Here, we present an APTR event in an adult subject with transfusion‐dependent thalassemia
Georgia Tzafa, Sophia Delicou, Ioanna Barla, Konstantina Theocharaki, Aggeliki Kondi, Athanassios D. Velentzas, Nikolaos Simantiris, Elli‐Anna Stylianaki, George Mpekoulis, Efthymia Pavlou, Niki Vassilaki, Ioannis V. Kostopoulos, Aikaterini Xydaki, Efrosyni Nomikou, Ioanna‐Katerina Aggeli, Nikolaos Thomaidis, Evangelos Gikas, Martina Samiotaki, Jerome Zoidakis, Constantina Politis, Marianna H. Antonelou   +20 more
wiley   +1 more source

A Case of Hemoglobin Sickle-D Punjab. [PDF]

Indian J Hematol Blood Transfus, 2020
Ali W, Jain M, Agarwal S, Kumar A.
europepmc   +1 more source

Serum of sickle cell disease patients contains fetal hemoglobin silencing factors secreted from leukocytes

, 2018
Tohru Ikuta,1 Hassan Sellak,1 Si-Yang Liu,2 Nadine Odo1 1Department of Anesthesiology and Perioperative Medicine, Medical College of Georgia, Augusta University, Augusta, GA, USA; 2Department of Biochemistry and Molecular Biology, Medical College of ...
Ikuta T, Odo N, Liu SY, Sellak H
core  

Fetal Hemoglobin in Sickle Hemoglobinopathies: High HbF Genotypes and Phenotypes

, 2020
Fetal hemoglobin (HbF) usually consists of 4 to 10% of total hemoglobin in adults of African descent with sickle cell anemia. Rarely, their HbF levels reach more than 30%.
Martin H. Steinberg
core   +1 more source

Uncovering the impact of the cardiovascular system on cerebrovascular health using MRI

Experimental Physiology, EarlyView.
Abstract Human cerebrovasculature is finely tuned to enable local changes in blood flow to meet the brain's demands, whilst protecting the brain from systemic changes in blood pressure, both acutely during a heartbeat and chronically over time. This review summarises cerebrovascular structure and function, their role in disease and neurodegeneration ...
Ian D. Driver, Kevin Murphy
wiley   +1 more source

Feasibility and utility of a sickle cell disease registry for research and patient management

, 2009
This thesis was submitted for the degree of Doctor of Philosophy and awarded by Brunel University.This thesis aimed to evaluate the feasibility and utility of a sickle cell disease registry for clinical patient management and research.
Gilmore, Annette
core  

Sickle Cell Hemoglobin Drugged with Cyclic Peptides is Aggregation Incompetent

Sickle cell disease is a monogenic blood disorder associated with a mutation in the HBB gene encoding for the β-globin of normal adult hemoglobin (HbA).
Nuno, Galamba
core   +1 more source