Results 161 to 170 of about 29,542 (277)

Transcranial Doppler Ultrasound Velocity Measurements in Children With Sickle Cell Disease in Kenya

open access: yeseJHaem, Volume 7, Issue 3, June 2026.
ABSTRACT Background Sickle cell disease (SCD) is the most common inherited haemoglobinopathy and poses a high public health burden in Sub‐Saharan Africa. Children with sickle cell anaemia are at a highrisk of ischemic stroke, and transcranial Doppler (TCD) ultrasonography helps identify those at highest risk for primary stroke prevention.
Catherine Mwalimu   +9 more
wiley   +1 more source

Association Between Micronutrients and Cognitive Performance Among Adolescents and Young Adults Living With Sickle Cell Disease in Kumasi, Ghana: A Cross‐Sectional Study

open access: yeseJHaem, Volume 7, Issue 3, June 2026.
ABSTRACT Aim Cognitive deficits are commonly reported in patients with sickle cell disease (SCD). Dietary micronutrient intake is a potential modifiable risk factor whose relationship with cognition in SCD patients remains poorly characterised. This study aimed to determine the association between dietary micronutrient intake and cognition among these ...
Albert Dennis Kegya   +4 more
wiley   +1 more source

Epigenetic Regulation in Cardiovascular Diseases: Mechanisms and Therapeutic Targets

open access: yesMedComm, Volume 7, Issue 6, June 2026.
Environmental and lifestyle exposures reshape the cardiovascular epigenome through coordinated regulation of DNA methylation, histone modifications, noncoding RNAs, and RNA methylation (m6A). These multilayered mechanisms drive enhancer‐centered regulatory network remodeling and epigenomic plasticity in cardiovascular diseases, highlighting emerging ...
Wangzheqi Zhang   +7 more
wiley   +1 more source

On‐Chip Evaluation of Red Blood Cell Deformability Through Transit Velocity Index in Hematological Diseases

open access: yesSmall, Volume 22, Issue 33, 12 June 2026.
The deformability of red blood cell is essential for smooth microcirculation. We propose a deformability index using a microfluidic platform with capillary‐like constrictions, based on the relationship between cell deformation and transit velocity through the constrictions. Its effectiveness and clinical potential have been demonstrated in applications
Kenji Kajitani   +9 more
wiley   +1 more source

Structure and function of tetrameric hemoglobins and their mutants at a molecular and cellular level.

open access: yes, 2011
The present Ph.D. thesis has focused on tetrameric hemoglobins (Hbs), both recombinant and natural, both from human origin and Antarctic fish, using a multidisciplinary approach based on spectroscopic, crystallographic and computational techniques.
Balsamo, Anna
core  

Cohort Study: Risk of Gallstones and Biliary Complications With Glucagon‐Like Peptide‐1 Receptor Agonists in Type 2 Diabetes

open access: yesUnited European Gastroenterology Journal, Volume 14, Issue 5, June 2026.
ABSTRACT Background Glucagon‐like peptide‐1 receptor agonists (GLP‐1 RAs) are widely prescribed for type 2 diabetes mellitus (T2DM) because of their benefits in glycemic control, weight reduction, and cardiovascular outcomes. This study evaluated the risk of gallbladder disease among diabetic patients treated with GLP‐1 RAs.
Mohamed H. Eldesouki   +7 more
wiley   +1 more source

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