Results 161 to 170 of about 204,284 (266)

TTP‐Like Syndrome and Subsequent Non‐Aneurysmal Subarachnoid Hemorrhage in HbSC Disease: A Case Report

Clinical Case Reports, Volume 14, Issue 9, September 2026.
ABSTRACT Sickle cell disease (SCD) with hemoglobin‐ (Hb‐) SC genotype is often considered a milder SCD variant, yet life‐threatening complications can occur. A 26‐year‐old man with HbSC disease presented with an infection triggered vaso‐occlusive crisis (VOC), acute chest syndrome (ACS), severe thrombocytopenia, Coombs‐negative hemolysis with ...
Benjamin Vieten, Jan Vorwerk, Jan Morf, Alice Dauth, Stefan Sondermann, Peter Schramm, Tobias Graf, Nikolas von Bubnoff, Lorenz Oelschläger, Cyrus Khandanpour   +9 more
wiley   +1 more source

Hydrocephalus and Diffuse Alveolar Hemorrhage as the Initial Manifestation of Systemic Lupus Erythematosus and Antiphospholipid Syndrome: A Case Report

Clinical Case Reports, Volume 14, Issue 9, September 2026.
ABSTRACT Systemic lupus erythematosus (SLE) is an autoimmune disease that can affect many systems, such as the central nervous system (CNS), cardiovascular, musculocutaneous, renal, and respiratory systems, etc. SLE can occur alone or in association with other autoimmune diseases, especially antiphospholipid syndrome (APS).
Ehsan Adib, Narges Gorbanmaleki, Amirreza Eterafi, Sara Jalali Jivan   +3 more
wiley   +1 more source

Therapeutic potential of haptoglobin in a murine model of sickle cell anemia. [PDF]

PLoS One
Dos Santos BC, Dos Santos MNN, Pedroso GA, de Oliveira BB, de Albuquerque DM, de Oliveira NR, Noronha DC, Costa FF, Corat MAF.   +8 more
europepmc   +1 more source

CRISPR‐Cas9 and precision editing technologies linking functional genomics to clinical translation in genetic diseases

Clinical and Translational Medicine, Volume 16, Issue 9, September 2026.
CRISPR‐Cas9 and precision editing technologies enable a variant‐mechanism‐driven framework for genetic disease research and therapeutic development. Pathogenic variants are first interpreted according to mutation type, coding or regulatory consequence, tissue context, and disease mechanism.
Zijing Wen, Jianming Su
wiley   +1 more source

Recurrent Sickle Cell Hepatopathy After Liver Transplantation Despite Guideline-Directed Red Blood Cell Exchange. [PDF]

ACG Case Rep J
Aslam MN, Weber M, Al-Hindawi A, Park S, Maddineni G, Pillai A.   +5 more
europepmc   +1 more source

Academic Performance Among Children With Sickle Cell Disease in Low‐ and Middle‐Income Countries: A Systematic Review

Health Science Reports, Volume 9, Issue 9, September 2026.
ABSTRACT Background and Aim Children with sickle cell disease (SCD) in low‐ and middle‐income countries (LMICs) face significant disease‐related challenges and socioeconomic status (SES) disparities that may negatively impact their academic performance. This systematic review synthesized existing evidence on academic performance among children with SCD
Shubaya K. Naggayi, Paul Bangirana, Simple Ouma, Mary Nyakato, Alison A. Kinengyere, Dickens Akena, Nancy S. Green, Richard Idro   +7 more
wiley   +1 more source

Subphenotypes of Sickle Cell Disease: A Guide to Targeting Treatment? [PDF]

Am J Hematol
Steinberg MH.
europepmc   +1 more source

Sickle cell trait and diabetes tests : what every healthcare provider should know [PDF]

According to the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), the hemoglobin A1C assay may be unreliable for diagnosing and monitoring diabetes and prediabetes in individuals with sickle cell trait (SCT) or other ...

core  

Strategies and mechanisms of precision genome engineering: From gene editing to genome writing

iMetaOmics, Volume 3, Issue 3, September 2026.
In this review, we examined the progression of genome manipulation from stochastic nuclease‐mediated cutting toward precise editing and programmable genome writing. We discussed tools like multi‐kilobase RNA‐guided integrators and Artificial Intelligence (AI)‐designed effectors and showed how these advances enable researchers to treat genomes as ...
Kerui Huang, Jianhong Tian, Wenyan Zhao, Siqin Zhang, Lixuan Xiang, Meiqing Yang, Lu Liu, Yazhou Huang, Ningyun Zhang, Lei Sun, Peng Xie, Nanyu Kuang, Hong Zhou, Chengfeng Qiu, Jun Yan, Xiaocheng Jiang, Qiang Tu, Yun Wang, Haoliang Hu, Youming Zhang   +19 more
wiley   +1 more source

Clinical Characteristics of Sickle Cell Disease Patients with Leg Ulcer in Murtala Muhammad Specialist Hospital, Kano, Nigeria. [PDF]

Niger Med J
Borodo AM, Ibrahim UM, Ibrahim H.
europepmc   +1 more source