Results 61 to 70 of about 29,542 (277)
Prenatal Diagnosis, EarlyView.ABSTRACT Sickle cell disease (SCD) affects millions worldwide but has limited treatment options, most of which carry significant side effects. At present, the only curative treatment for SCD is allogeneic or gene‐modified autologous hematopoietic stem cell (HSC) transplantation (Tx).
Oluwaseun O. Babatunde +4 more
wiley +1 more source
Haematologica, 2016 Increased fetal hemoglobin levels lessen the severity of symptoms and increase the lifespan of patients with sickle cell disease. Hydroxyurea, the only drug currently approved for the treatment of sickle cell disease, is not effective in a large ...
Angela Rivers +9 more
doaj +1 more source
Growth and Pubertal Development in Children With Sickle Cell Anaemia at Muhimbili National Hospital 2010 [PDF]
, 2011 Sickle cell anaemia (SCA) is a genetic disorder with multisystem manifestations. Paediatricians and general practitioners dealing with these patients need to know the overview of the genetics, diagnosis, clinical manifestations, and treatment of sickle ...
Jacob, Theopista
core
Cross Sectional Study of Prenatal Diagnosis Uptake Among Individuals With Genetic Conditions
Prenatal Diagnosis, EarlyView.ABSTRACT Objective Prenatal diagnostic genetic testing allows for early identification of significant fetal conditions and enables informed decision‐making regarding management options. The aim of this study was to assess prenatal testing practice among individuals with genetic conditions.
Ebunoluwa Ojo +4 more
wiley +1 more source
Evaluation of the renal function among sickle cell patients: a cross-sectional study
Italian Journal of MedicineThis cross-sectional study aimed to explore the implications and effects of hematological and kidney function patterns in individuals with sickle cell disorder (SCD) residing in the Jazan Region of Saudi Arabia.
Talal Qadah, Anwar Refaei
doaj +1 more source
Patients with sickle cell disease taking hydroxyurea in the Hemocentro Regional de Montes Claros
Revista Brasileira de Hematologia e Hemoterapia, 2011 BACKGROUND: The development of therapies for sickle cell disease has received special attention, particularly those that reduce the polymerization of hemoglobin S.
Fernanda Kelle de Souza Santos +1 more
doaj +1 more source
Sickle Cell Disease: Historical Overview and Current Therapies
Prenatal Diagnosis, EarlyView.ABSTRACT Sickle cell disease (SCD) affects millions worldwide, yet the limited treatment options currently available do not always adequately control the disease and carry significant side effects. At present, the only curative treatment is hematopoietic stem cell (HSC) transplantation, a procedure that carries considerable challenges and numerous ...
Oluwaseun O. Babatunde +4 more
wiley +1 more source
SICKLE CELL DISEASE - CASE REPORTS
Journal of Nepal Medical Association, 2003 Sickle cell diseases are inherited hematological diseases, prevalent in certain parts of the world. We report two cases of sickle cell diseases, first being sickle cell b-thalassaemia and second homozygous sickle cell disease (SS).
Ram Chandra Adhikari +5 more
doaj +1 more source
Hemoglobin genes; Sickle-cell anemia - Thalassemias [PDF]
, 2009 Educational Items on Hemoglobin genes; Sickle-cell anemia ...
Huret, JL, Troussard, X
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