Results 71 to 80 of about 46,727 (267)
SICKLE CELL DISEASE - CASE REPORTS
Journal of Nepal Medical Association, 2003 Sickle cell diseases are inherited hematological diseases, prevalent in certain parts of the world. We report two cases of sickle cell diseases, first being sickle cell b-thalassaemia and second homozygous sickle cell disease (SS).
Ram Chandra Adhikari +5 more
doaj +1 more source
Microalbuminuria as Predictor of Early Glomerular Injury in Children and Adolescents with Sickle Cell Anaemia at Muhimbili National Hospital Dar es Salaam, Tanzania 2012 [PDF]
, 2012 Microalbuminuria (MA) is the earliest marker of various diseases affecting the renal system. Its relevance in children and adolescents with sickle cell anaemia (SCA), who are known to be prone to renal complications, has not been fully explored in our ...
Christopher, Richard
core
Compound Heterozygosity for Hemoglobin S and Hemoglobin LuLu Island
American Journal of Hematology, EarlyView.
Dana Lewis +4 more
wiley +1 more source
Small, EarlyView.The deformability of red blood cell is essential for smooth microcirculation. We propose a deformability index using a microfluidic platform with capillary‐like constrictions, based on the relationship between cell deformation and transit velocity through the constrictions. Its effectiveness and clinical potential have been demonstrated in applications
Kenji Kajitani +9 more
wiley +1 more source
Hydroxyurea Treatment for Sickle Cell Disease
The Scientific World Journal, 2002 High fetal hemoglobin (HbF) levels inhibit the polymerization of sickle hemoglobin (HbS) and reduce the complications of sickle cell disease. Pharmacologic agents that can reverse the switch from γ- to β-chain synthesis — γ-globin chains characterize HbF,
Martin H. Steinberg
doaj +1 more source
Pulmonary hypertension in adolescents with sickle cell disease [PDF]
, 2016 Sickle cell disease consists of a group of disorders that have a similar mutation in at least one of the beta-globin chains of hemoglobin. This results in a change of the hemoglobin to sickle shaped cells when in the deoxygenated state.
Akinyemi, Katherine
core +1 more source
The human ankyrin 1 promoter insulator sustains gene expression in a β-globin lentiviral vector in hematopoietic stem cells. [PDF]
, 2015 Lentiviral vectors designed for the treatment of the hemoglobinopathies require the inclusion of regulatory and strong enhancer elements to achieve sufficient expression of the β-globin transgene.
Baldwin, Kismet M +12 more
core +4 more sources
Acta Paediatrica, EarlyView.Importance of psychosocial support. ABSTRACT Aim The aim of this scoping review was to identify, examine, and summarize available evidence regarding psychosocial supports provided to children with a chronic disease when admitted to hospital and their parents. Method The JBI methodology for conducting and reporting scoping reviews was followed.
Lyndsay Jerusha MacKay +6 more
wiley +1 more source
High‐Altitude Hypoxemia in Adults With Sickle Cell Disease (SCD)
American Journal of Hematology, EarlyView.
Mofiyin A. Obadina +4 more
wiley +1 more source
Revista Brasileira de Hematologia e Hemoterapia, 2009 The most highly prevalent inherited disease in Brazil and in the world, sickle cell anemia, is considered a public health problem. Characterized by homozygosis for the hemoglobin S gene, the individual has a range of signs and symptoms that require ...
Leonardo F. Soares +5 more
doaj +1 more source