Results 171 to 180 of about 13,066 (196)
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Paroxysmal Cold Hemoglobinuria
CRC Critical Reviews in Clinical Laboratory Sciences, 1978The clinical and hematological features of a rare autoimmune disorder, PCH, are reviewed. Based on the case reports of 24 patients suffering from this disease, the presence of cold hemolysins in the sera of these patients as the main cause for the red cell destruction following exposure to cold is further discussed.
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PAROXYSMAL COLD HEMOGLOBINURIAS
Archives of Internal Medicine, 1948DRESSLER 1 is credited with having first reported observations on a case of "paroxysmal cold hemoglobinuria," a symptom complex now known to have two separate and distinct etiologic bases. The first and more generally recognized type is syphilitic paroxysmal cold hemoglobinuria, a disease seen in a small percentage of persons with syphilis and caused ...
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Paroxysmal Nocturnal Hemoglobinuria
Journal of Computer Assisted Tomography, 1993Paroxysmal nocturnal hemoglobinuria (PNH) is an acquired hemolytic disorder, characterized by hemosiderin deposition in the proximal renal tubules.We examined six cases of PNH with MRI including gradient echo imaging.On T2- and T2*-weighted imaging a characteristic hypointense pattern was noted in five of six patients with PNH.
Y O, Tanaka, I, Anno, Y, Itai, T, Abe
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Paroxysmal Nocturnal Hemoglobinuria Revisited
New England Journal of Medicine, 1983Immunologic systems are now known to have a major role in the pathophysiology of many human disease processes. One such system is serum complement.
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American Journal of Diseases of Children, 1933
It is well known that with some remedies, e. g., arsphenamine, mercury, bismuth and iodide of potassium, several years of continuous administration are required to ensure complete recovery from paroxysmal hemoglobinuria. Recently, S. Inamori of the department of pediatrics at Manchuria Medical College reported that the inoculation of Spirochaeta morsus-
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It is well known that with some remedies, e. g., arsphenamine, mercury, bismuth and iodide of potassium, several years of continuous administration are required to ensure complete recovery from paroxysmal hemoglobinuria. Recently, S. Inamori of the department of pediatrics at Manchuria Medical College reported that the inoculation of Spirochaeta morsus-
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Acute Paroxysmal Cold Hemoglobinuria
Transfusion Medicine Reviews, 1989Over eighty years have passed since Donath and Landsteiner identified the syndrome of PCH and reported an in vitro test for its diagnosis. The accuracy of their observations, and the usefulness of the DL procedure has persisted. PCH has been investigated over the years providing further information regarding antibody specificity and serological ...
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SYPHILITIC PAROXYSMAL COLD HEMOGLOBINURIA
Annals of Internal Medicine, 1957Excerpt Paroxysmal cold hemoglobinuria is a rare hemolytic disorder of which there are two distinct varieties.
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Paroxysmal Nocturnal Hemoglobinuria in Children
Pediatric Drugs, 2007Paroxysmal nocturnal hemoglobinuria (PNH), an acquired hematologic disorder characterized by intravascular hemolysis, nocturnal hemoglobinuria, thrombotic events, serious infections, and bone marrow failure, is very rare in children. PNH is caused by a somatic mutation of the phosphatidylinositol glycan (GPI) complementation class A (PIGA) gene ...
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Paroxysmal Nocturnal Hemoglobinuria
New England Journal of Medicine, 1952THE most accurate method of study of any disease is enlightened statistical analysis of a large number of cases. However, paroxysmal nocturnal hemoglobinuria is a rare blood dyscrasia; approximately 45 cases, not all of convincing authenticity, have appeared in the literature to this time.9 Consequently, no physician or group of physicians is likely to
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Paroxysmal Nocturnal Hemoglobinuria
New England Journal of Medicine, 1961PAROXYSMAL nocturnal hemoglobinuria is a disease with a fascinating diversity of challenges and implications. These have prompted numerous clinical and basic investigations. The clinical features are often bizarre and may be misleading, even with the most typical presentation of abdominal pain, fatigue, weakness, anemia and dark urine and with venous ...
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