Results 91 to 100 of about 6,457,465 (175)

Biocide Response of Candida auris

Mycoses, Volume 69, Issue 3, March 2026.
ABSTRACT Candida auris is an emerging multidrug‐resistant yeast demonstrating remarkable persistence in healthcare environments, contributing to nosocomial transmission and outbreak persistence. Increasing disinfectant failure reports have raised concerns regarding infection control policies, as environmental reservoirs play central roles in its spread.
Sidre Erganis, Ali Ozturk, Elif Ayca Sahin, Ayse Kalkanci   +3 more
wiley   +1 more source

Restraining Staphylococcus aureus Virulence Factors and Quorum Sensing through Lactic Acid Bacteria Supernatant Extracts

Antibiotics
The escalating prevalence of antibiotic-resistant bacteria poses a grave threat to human health, necessitating the exploration of novel alternatives to conventional antibiotics.
Myriam Anabel Díaz, Esteban Gabriel Vega-Hissi, María Amparo Blázquez, María Rosa Alberto, Mario Eduardo Arena   +4 more
doaj   +1 more source

The Rate of Folding Dictates Substrate Secretion by the Escherichia coli Hemolysin Type 1 Secretion System*

Journal of Biological Chemistry, 2010
Secretion of the Escherichia coli toxin hemolysin A (HlyA) is catalyzed by the membrane protein complex HlyB-HlyD-TolC and requires a secretion sequence located within the last 60 amino acids of HlyA.
Patrick J. Bakkes, S. Jenewein, S. Smits, I. Holland, L. Schmitt   +4 more
semanticscholar   +1 more source

An Imidazo[2,1‐b][1,3,4]thiadiazole Derivative Inhibits the Virulence Factor α‐Hemolysin by Blocking the Pullout of Its Stem Domain

ChemMedChem, Volume 21, Issue 4, 25 February 2026.
A high‐throughput cellular screen based on Ca2+ influx in U937 monocytic cells identified thiadiazoles as small‐molecule inhibitors of α‐hemolysin, a key virulence factor of Staphylococcus aureus. The thiadiazole 1 prevents pore formation by a dual mechanism that prevents stem loop unfolding as well as membrane attachment.
Vadim S. Korotkov, Peer Lukat, Raffaella Di Lucrezia, Aditya Shekhar, Carsten Degenhart, Randi Diestel, Ursula Bilitewski, Klaus Dinkel, Wulf Blankenfeldt, Mark Brönstrup   +9 more
wiley   +1 more source

MgaSpn and H-NS: two unrelated global regulators with similar DNA-binding properties

Frontiers in Molecular Biosciences, 2016
Global regulators play an essential role in the adaptation of bacterial cells to specific niches. Bacterial pathogens thriving in the tissues and organs of their eukaryotic hosts are a well-studied example.
Virtu Solano-Collado, Mário Hüttener, Manuel Espinosa, Antonio Juárez, Antonio Juárez, Alicia Bravo   +5 more
doaj   +1 more source

Roles of the Hcp family proteins in the pathogenicity of Salmonella typhimurium 14028s

Virulence, 2020
The type VI secretion system (T6SS) is a new secretion system that is widely distributed among Gram-negative bacteria. The core component hemolysin-coregulated protein (Hcp) can be used as both its structural protein and secretory protein or chaperone ...
Ping Wang, Jun-Fang Dong, Ren-Qing Li, Lei Li, Qing-Hua Zou   +4 more
doaj   +1 more source

Bottom‐up Strategies for Generating Polymer Protocells That Mimic Cellular Communication

Chemistry – A European Journal, Volume 32, Issue 8, 23 February 2026.
This review focuses on polymeric protocells produced using a bottom‐up approach. Polymer‐based assemblies guarantee stability and designability by adjusting the properties of the amphiphilic copolymers used. The review covers protocell architectures, production, and their intra‐ and intercellular communication mechanisms.
Gloria Saorin, Xinan Huang, Voichita Mihali, Cornelia G. Palivan   +3 more
wiley   +1 more source

Unidirectional single-file transport of full-length proteins through a nanopore

bioRxiv, 2021
Luning Yu, X. Kang, Fanjun Li, B. Mehrafrooz, Amr Makhamreh, Ali Fallahi, Joshua C. Foster, A. Aksimentiev, Min Chen, M. Wanunu   +9 more
semanticscholar   +1 more source

Hemolysin, Protease, and EPS Producing Pathogenic Aeromonas hydrophila Strain An4 Shows Antibacterial Activity against Marine Bacterial Fish Pathogens

, 2010
A pathogenic Aeromonas hydrophila strain An4 was isolated from marine catfish and characterized with reference to its proteolytic and hemolytic activity along with SDS-PAGE profile (sodium dodecyl sulphate-Polyacrylamide gel electrophoresis) of ECPs ...
A. Pandey, M. Naik, S. K. Dubey
semanticscholar   +1 more source

β-Barrel membrane protein folding and structure viewed through the lens of α-hemolysin

Biochimica et Biophysica Acta (BBA) - Biomembranes, 2003
The beta-barrel is a transmembrane structural motif commonly encountered in bacterial outer membrane proteins and pore-forming toxins (PFTs). Alpha-hemolysin (alphaHL) is a cytotoxin secreted by Staphylococcus aureus that assembles from a water-soluble monomer to form a membrane-bound heptameric beta-barrel on the surface of susceptible cells ...
Montoya, Michelle, Gouaux, Eric
openaire   +2 more sources