Results 11 to 20 of about 21,085 (234)

Consensus recommendations for the diagnosis and management of hemophagocytic lymphohistiocytosis associated with malignancies [PDF]

Haematologica, 2015
The hyperinflammatory syndrome hemophagocytic lymphohistiocytosis can occur in the context of malignancies. Malignancy-triggered hemophagocytic lymphohistiocytosis should be regarded seperately from hemophagocytic lymphohistiocytosis during ...
Kai Lehmberg, Kim E. Nichols, Jan-Inge Henter, Michael Girschikofsky, Tatiana Greenwood, Michael Jordan, Ashish Kumar, Milen Minkov, Paul La Rosée, Sheila Weitzman   +9 more
doaj   +2 more sources

Babesia microti infection and hemophagocytic lymphohistiocytosis in an immunocompetent patient

International Journal of Infectious Diseases, 2017
Babesiosis is a rare and potentially severe tick-borne illness endemic to the Northeastern and upper Midwestern regions of the USA. Hemophagocytic lymphohistiocytosis is an uncommon condition resulting from over-activation of the immune system. The first
Shanette A. Go, Vania H. Phuoc, Sarah E. Eichenberg, Zelalem Temesgen, Thomas J. Beckman   +4 more
doaj   +2 more sources

Mycobacterium iranicum bacteremia and hemophagocytic lymphohistiocytosis: a case report

BMC Research Notes, 2017
Background Mycobacterium iranicum has recently been recognised as an opportunistic human pathogen. Although infectious conditions represent frequent triggers for hemophagocytic lymphohistiocytosis, non-tuberculous mycobacterial infections are rarely ...
Simon Grandjean Lapierre, Alexandre Toro, Michel Drancourt   +2 more
doaj   +2 more sources

Prolonged hemophagocytic lymphohistiocytosis syndrome as an initial presentation of Hodgkin lymphoma: a case report [PDF]

Journal of Medical Case Reports, 2008
Introduction Hemophagocytic lymphohistiocytosis is an immune-mediated syndrome that typically has a rapidly progressive course that can result in pancytopenia, coagulopathy, multi-system organ failure and death.
Chan Kathryn, Behling Eric, Strayer David S, Kocher William S, Dessain Scott K   +4 more
doaj   +3 more sources

Hemophagocytic lymphohistiocytosis: a case series of a Brazilian institution

Revista Brasileira de Hematologia e Hemoterapia, 2014
Objective:To describe the clinical and laboratory presentation of hemophagocytic lymphohistiocytosis in children treated at a referral institution.Methods:A retrospective descriptive study was carried out of seven children diagnosed with hemophagocytic ...
Daniela Guimarães Rocha Ferreira, Paulo do Val Rezende, Mitiko Murao, Marcos Borato Viana, Benigna Maria de Oliveira   +4 more
doaj   +2 more sources

Lymphoma-associated hemophagocytic lymphohistiocytosis

Hematology, Transfusion and Cell Therapy
Hemophagocytic lymphohistiocytosis is a severe, rare condition characterized by excessive immune activation, leading to significant morbidity and mortality.
Thomás de Souza Patto Marcondes, Carlos Sérgio Chiattone, Rafael Dezen Gaiolla   +2 more
doaj   +2 more sources

Hemophagocytic lymphohistiocytosis associated with anaplasmosis [PDF]

Journal of Global Infectious Diseases, 2017
Hemophagocytic lymphohistiocytosis (HLH) is a hyperinflammatory syndrome characterized by unregulated macrophage and T-lymphocyte activation resulting in cytokine overproduction and subsequent histiocytic phagocytosis. Variant infections, particularly viruses have been postulated as the inciting factor for this potentially fatal disease.
Tamara M Johnson, Melinda S Brown, Mohamed Rabbat, Jihad Slim   +3 more
openaire   +4 more sources

Hemophagocytic Lymphohistiocytosis [PDF]

Archives of Pathology & Laboratory Medicine, 2021
Context.— Hemophagocytic lymphohistiocytosis (HLH) is a rare, life-threatening disorder of immune regulation that can eventually result in end-organ damage and death. HLH is characterized by uncontrolled activation of cytotoxic T lymphocytes, natural killer cells, and macrophages that can lead to a cytokine ...
Tanya Sajan, Ponnatt, Cullen M, Lilley, Kamran M, Mirza   +2 more
openaire   +2 more sources

Precision immunomodulation for pediatric hemophagocytic lymphohistiocytosis in intensive care. [PDF]

Pediatr Investig
This review presents a bedside framework for recognizing pediatric hemophagocytic lymphohistiocytosis and cytokine storm, stabilizing organ dysfunction, identifying the underlying phenotype, selecting targeted immunomodulation, considering extracorporeal adjuncts, and reassessing response within 24–72 h. ABSTRACT Hemophagocytic lymphohistiocytosis (HLH)
Lilitwat W, Bhandari P.
europepmc   +2 more sources

Hemophagocytic Lymphohistiocytosis

Pediatrics In Review, 2022
Hemophagocytic lymphohistiocytosis (HLH) is an aggressive life-threatening disease that consists of uncontrolled activated lymphocytes and macrophages that secrete excessive cytokines. Symptoms and laboratory findings of HLH include prolonged fever, cytopenia, hepatosplenomegaly, liver dysfunction, hypertriglyceridemia, hyperferritinemia, increased ...
Hannah, Major-Monfried, Suzanne, Friedman, Scott, Moerdler   +2 more
openaire   +6 more sources