Results 11 to 20 of about 13,346 (189)

Hemophagocytic Lymphohistiocytosis [PDF]

Archives of Pathology & Laboratory Medicine, 2021
Context.— Hemophagocytic lymphohistiocytosis (HLH) is a rare, life-threatening disorder of immune regulation that can eventually result in end-organ damage and death. HLH is characterized by uncontrolled activation of cytotoxic T lymphocytes, natural killer cells, and macrophages that can lead to a cytokine ...
Tanya Sajan, Ponnatt, Cullen M, Lilley, Kamran M, Mirza   +2 more
openaire   +3 more sources

Hemophagocytic Lymphohistiocytosis

Pediatrics In Review, 2022
Hemophagocytic lymphohistiocytosis (HLH) is an aggressive life-threatening disease that consists of uncontrolled activated lymphocytes and macrophages that secrete excessive cytokines. Symptoms and laboratory findings of HLH include prolonged fever, cytopenia, hepatosplenomegaly, liver dysfunction, hypertriglyceridemia, hyperferritinemia, increased ...
Hannah, Major-Monfried, Suzanne, Friedman, Scott, Moerdler   +2 more
openaire   +6 more sources

[Hemophagocytic lymphohistiocytosis]. [PDF]

Nihon rinsho. Japanese journal of clinical medicine, 2013
Hemophagocytic lymphohistiocytosis is a life-threatening condition associated with multiple organ dysfunctions. This entity is related to inappropriate stimulation and proliferation of cytotoxic lymphocytes and macrophages inducing phagocytosis of blood cells.
J-M, Michot, M, Hié, L, Galicier, O, Lambotte, M, Michel, C, Bloch-Queyrat, O, Hermine   +6 more
  +8 more sources

Hemophagocytic Lymphohistiocytosis [PDF]

Indian Journal of Hematology and Blood Transfusion, 2012
Hemophagocytic lymphohistiocytosis (HLH) is an immune disorder characterized by uncontrolled inflammation due to defective immune response. It may be familial or acquired, but both share a common feature of threatening the life of a patient and may lead to death unless treated by appropriate treatment. Here in we report a case of adult HLH.
A M V R, Narendra, G, Varun Kumar, A, Krishna Prasad, M, Shetty, Megha S, Uppin, V R, Srinivasan   +5 more
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Approaching hemophagocytic lymphohistiocytosis

Frontiers in Immunology, 2023
Hemophagocytic Lymphohistiocytosis (HLH) is a rare clinical condition characterized by sustained but ineffective immune system activation, leading to severe and systemic hyperinflammation. It may occur as a genetic or sporadic condition, often triggered by an infection.
Aurora Chinnici, Aurora Chinnici, Linda Beneforti, Linda Beneforti, Francesco Pegoraro, Francesco Pegoraro, Irene Trambusti, Annalisa Tondo, Claudio Favre, Maria Luisa Coniglio, Elena Sieni   +10 more
openaire   +4 more sources

Screening of hemophagocytic lymphohistiocytosis in children with severe sepsis in pediatric intensive care

Science Progress, 2021
Background: We sought to screen for clinical and laboratory features of hemophagocytic lymphohistiocytosis among pediatric patients with severe sepsis.
Zeinab A El-Sayed, Rasha H El-Owaidy, Mohammed A Khamis, Ahmed R Rezk   +3 more
doaj   +1 more source

Lamotrigine-induced hemophagocytic lymphohistiocytosis with Takotsubo cardiomyopathy: a case report

Journal of Medical Case Reports, 2019
Background Hemophagocytic lymphohistiocytosis is a rare hematological syndrome characterized by excessive and uncontrolled activation of the immune system.
Jenny Y. Zhou, Jordan A. Martinez, John Paul Shen   +2 more
doaj   +1 more source

Pediatric hemophagocytic lymphohistiocytosis [PDF]

Blood, 2020
Abstract Hemophagocytic lymphohistiocytosis (HLH) is a syndrome describing patients with severe systemic hyperinflammation. Characteristic features include unremitting fever, cytopenias, hepatosplenomegaly, and elevation of typical HLH biomarkers.
Scott W, Canna, Rebecca A, Marsh
openaire   +2 more sources

A 9month-old-boy with atypical hemophagocytic lymphohistiocytosis

Mediterranean Journal of Hematology and Infectious Diseases, 2017
Hemophagocytic lymphohistiocytosis is a life-threatening hyperinflammation caused by uncontrolled proliferation of activated lymphocytes and histiocytes. Often, Hemophagocytic lymphohistiocytosis is an acquired syndrome. We report a case of a 9 month-old-
Monia Ouederni, MONIA BEN KHALED, Samia Rekaya, Ilhem Ben Fraj, Fethi Mellouli, Mohamed Bejaoui   +5 more
doaj   +1 more source

Hemophagocytic lymphohistiocytosis in adults [PDF]

Baylor University Medical Center Proceedings, 2020
Hemophagocytic lymphohistiocytosis (HLH) is an underrecognized disorder due to the variability of its presentation and the fact that in adults, its diagnosis is based on cumbersome, pediatric-based criteria. Data regarding demographics, underlying causes, clinical features, laboratory results, complications, treatments received, and clinical outcomes ...
Yadav Pandey, Dinesh Atwal, Manojna Konda, Milan Bimali, Derek Middleton, Naveen Yarlagadda, Belal Firwana, Appalanaidu Sasapu   +7 more
openaire   +2 more sources