Results 41 to 50 of about 21,085 (234)

Hemophagocytosis in the Acute Phase of Fatal Kawasaki Disease in a 4 Month-Old Girl

Balkan Medical Journal, 2016
Background: Kawasaki disease is a systemic vasculitis predominately affecting coronary arteries. Hemophagocytic lymphohistiocytosis can complicate the course of Kawasaki disease.
Vehbi Doğan, Erhan Karaaslan, Samet Özer, Rüveyda Gümüşer, Resul Yılmaz   +4 more
doaj   +1 more source

Pediatric hemophagocytic lymphohistiocytosis [PDF]

Blood, 2020
Abstract Hemophagocytic lymphohistiocytosis (HLH) is a syndrome describing patients with severe systemic hyperinflammation. Characteristic features include unremitting fever, cytopenias, hepatosplenomegaly, and elevation of typical HLH biomarkers.
Scott W, Canna, Rebecca A, Marsh
openaire   +2 more sources

Evaluation of children with haemophagocytic lymphohistiocytosis (HLH) at Red Cross War Memorial Children's Hospital 1991-2010 [PDF]

, 2011
Includes bibliographical references.Haemophagocytic Lymphohistiocytosis (HLH) is a rare haematological disorder in children. However, this is probably an underestimation due to the difficulty in diagnosing the disease.
Switala, Juli
core   +1 more source

Hemophagocytic lymphohistiocytosis in adults [PDF]

Baylor University Medical Center Proceedings, 2020
Hemophagocytic lymphohistiocytosis (HLH) is an underrecognized disorder due to the variability of its presentation and the fact that in adults, its diagnosis is based on cumbersome, pediatric-based criteria. Data regarding demographics, underlying causes, clinical features, laboratory results, complications, treatments received, and clinical outcomes ...
Yadav Pandey, Dinesh Atwal, Manojna Konda, Milan Bimali, Derek Middleton, Naveen Yarlagadda, Belal Firwana, Appalanaidu Sasapu   +7 more
openaire   +2 more sources

Successful use of emapalumab in refractory hemophagocytic lymphohistiocytosis in a child with Chédiak–Higashi syndrome: a case report

Journal of Medical Case Reports, 2023
Background Hemophagocytic lymphohistiocytosis is a life-threatening disease heralded by fever, cytopenia, hepatosplenomegaly, and multisystem organ failure.
Ali AlAhmari, Haitham Khogeer
doaj   +1 more source

Hemophagocytic lymphohistiocytosis

Hematology/Oncology and Stem Cell Therapy, 2009
Hematol Oncol Stem Cell Ther 2(2) Second Quarter 2009 hemoncstem.edmgr.com 367 Hemophagocytic lymphohistiocytosis (HLH) is an unusual and rare syndrome characterized by fever, splenomegaly, pancytopenia, and the pathologic finding of hemophagocytosis (phagocytosis by macrophages of erythrocytes, leukocytes, platelets, and their precursors) in bone ...
Mitra, Bhaskar, Shrivastav, Ankit, Mukherjee, Krishnendu, Ghosh, Asit   +3 more
openaire   +2 more sources

A Hematopathology Case Study of Familial Hemophagocytic Lymphohistiocytosis (HLH)

, 2022
Hemophagocytic lymphohistiocytosis is a rare hematologic disorder caused by dysregulated immune activation and carries a high rate of mortality. It is categorized broadly into Primary (Familial ) and secondary types.
Dr. Lila Rani Vijayaraghavan, Dr. Siyad, Dr. Anjaly S S   +2 more
core   +1 more source

The syndrome of hemophagocytic lymphohistiocytosis in primary immunodeficiencies: implications for differential diagnosis and pathogenesis

Haematologica, 2015
Hemophagocytic lymphohistiocytosis is a hyperinflammatory syndrome defined by clinical and laboratory criteria. Current criteria were created to identify patients with familial hemophagocytic lmyphohistiocytosis in immediate need of immunosuppressive ...
Sebastian FN Bode, Sandra Ammann, Waleed Al-Herz, Mihaela Bataneant, Christopher C Dvorak, Stephan Gehring, Andrew Gennery, Kimberly C Gilmour, Luis I Gonzalez-Granado, Ute Groß-Wieltsch, Marianne Ifversen, Jenny Lingman-Framme, Susanne Matthes-Martin, Rolf Mesters, Isabelle Meyts, Joris M van Montfrans, Jana Pachlopnik Schmid, Sung-Yun Pai, Pere Soler-Palacin, Uta Schuermann, Volker Schuster, Markus G. Seidel, Carsten Speckmann, Polina Stepensky, Karl-Walter Sykora, Bianca Tesi, Thomas Vraetz, Catherine Waruiru, Yenan T. Bryceson, Despina Moshous, Kai Lehmberg, Michael B Jordan, Stephan Ehl   +32 more
doaj   +1 more source

Neurological presentation of hemophagocytic lymphohistiocytosis [PDF]

, 2015
Hemophagocytic lymphohistiocytosis (HLH) is an inflammatory disorder arising from defects in critical regulatory pathways responsible for termination of inflammatory response.
Żur-Wyrozumska, Kamila, Róg, Teresa, Mensah-Glanowska, Patrycja, Szczudlik, Andrzej   +3 more
core   +1 more source

Mutations affecting mRNA splicing are the most common molecular defect in patients with familial hemophagocytic lymphohistiocytosis type 3

Haematologica, 2008
Mutations of UNC13D have been described in patients affected by familial hemophagocytic lymphohistiocytosis (FHL3). The Munc13-4 protein contributes to the priming of the secretory granules.
Alessandra Santoro, Sonia Cannella, Antonino Trizzino, Giuseppa Bruno, Carmen De Fusco, Luigi D. Notarangelo, Daniela Pende, Gillian M. Griffiths, Maurizio Aricò   +8 more
doaj   +1 more source