Results 181 to 190 of about 13,301,732 (374)

A Bayesian Approach for Selecting Relevant External Data (BASE): Application to a study of Long-Term Outcomes in a Hemophilia Gene Therapy Trial [PDF]

arXiv
Gene therapies aim to address the root causes of diseases, particularly those stemming from rare genetic defects that can be life-threatening or severely debilitating. Although an increasing number of gene therapies have received regulatory approvals in recent years, understanding their long-term efficacy in trials with limited follow-up time remains ...
arxiv  

Novikov operad is not Koszul [PDF]

arXiv, 2009
An algebra with identities $a\circ(b\circ c-c\circ b)=(a\circ b)\circ c-(a\circ c)\circ b$ and $a\circ(b\circ c)=b\circ(a\circ c)$ is called Novikov. We show that Novikov operad is not Koszul.
arxiv  

A Dutch family with moderately severe hemophilia B (Factor IX_Heerde) has a missense mutation identical to that of factor lX_{London 2} [PDF]

, 1989
S R Poort, E Briët, R M Bertina, P H Reitsma   +3 more
openalex   +1 more source

Treatment of hemophilia B: focus on recombinant factor IX

Biologics: Targets & Therapy, 2013
Massimo Franchini, Francesco Frattini, Silvia Crestani, Cinzia Sissa, Carlo BonfantiDepartment of Transfusion Medicine and Hematology, Carlo Poma Hospital, Mantua, ItalyAbstract: Hemophilia B is a recessive X-linked bleeding disorder characterized by ...
Franchini M, Frattini F, Crestani S, Sissa C, Bonfanti C   +4 more
doaj  

SEARCHING FOR HIGGS BOSONS ON LHC USING $b$-TAGGING [PDF]

arXiv, 1995
We demonstrate that the detection of the SM and MSSM Higgs bosons will be possible at the LHC via $t\anti t b\anti b$ and $b\anti b b\anti b$ final state, provided $b$-tagging can be performed with good efficiency and purity.
arxiv  

Comorbidity and Mortality in Men and Women With Haemophilia in Three Nordic Countries–Comparisons to Matched Controls

Haemophilia, EarlyView.
ABSTRACT Introduction Comorbidities and public health conditions in haemophilia are receiving increasing attention. Aim To analyse the prevalence of comorbidities and mortality in people with haemophilia (PwH) compared to matched controls in subgroups (factor consumption and sex).
Katarina Steen Carlsson, Jan Astermark, Fariba Baghaei, Elisabeth Brodin, Eva Funding, Margareta Holmström, Klaus Österholm, Sofia Bergenstråle, Stefan Lethagen   +8 more
wiley   +1 more source

Multicenter Study of Diagnostic Tool for Patients with Hemophilia: From Bedside to Comprehensive Investigations

The Application of Clinical Genetics, 2023
Ampaiwan Chuansumrit,1 Rungrote Natesirinilkul,2 Nongnuch Sirachainan,1 Praguywan Kadegasem,1 Pacharapan Surapolchai,3 Noppawan Tangbubpha,1 Ketsuda Kempka,1 Tanyanee Khlangtan1 1Department of Pediatrics, Faculty of Medicine, Ramathibodi Hospital ...
Chuansumrit A, Natesirinilkul R, Sirachainan N, Kadegasem P, Surapolchai P, Tangbubpha N, Kempka K, Khlangtan T   +7 more
doaj  

E-theory is a special case of KK-theory [PDF]

arXiv, 2002
Let A and B be $C^*$-algebras, A separable, and B $\sigma$-unital and stable. It is shown that there are natural isomorphisms $E(A,B)=KK(SA,Q(B))=[SA,Q(B)\otimes K]$, where $SA=C_0(0,1)\otimes A$, $[\cdot,\cdot]$ denotes the set of homotopy classes of *-homomorphisms, $Q(B) = M(B)/B$ is the generalized Calkin algebra and K denotes the $C^*$-algebra of ...
arxiv  

Use of a BamHI polymorphism in the factor IX gene for the determination of hemophilia B carrier status [PDF]

, 1986
CW Hay, KA Robertson, S-L. Yong, AR Thompson, GH Growe, RT MacGillivray   +5 more
openalex   +1 more source

Ratio of Von Willebrand Collagen Binding Assay and Von Willebrand Antigen Can Predict Multimer Size in Von Willebrand Disease

Haemophilia, EarlyView.
ABSTRACT Background Von Willebrand disease (vWD) is a common bleeding disorder with different subtypes. Laboratory diagnosis is challenging, involving several expensive and complex assays. The von Willebrand factor (vWF) collagen binding assay (VWF:CB) has been described to improve the diagnosis of vWD, but there is a lack of consensus and its ...
Adrian Kimiaei, Iva Pruner, Maria Farm, Margareta Holmström, Natali Karandyszowska, Maria Bruzelius, Jovan Antovic, Anna Ågren   +7 more
wiley   +1 more source