Results 61 to 70 of about 18,147 (215)
Advanced Science, EarlyView.Programmable DNA framework captors effectively deplete circulatingtransforming growth factor‐β1 (TGFβ1) through fast systemic clearance and reshape the tumor immune microenvironment, alleviating immunosuppression to inhibit tumor progression. Abstract Efficient modulation of pivotal immune‐regulatory molecules to leverage the tumor microenvironment ...
Xiao Chen +7 more
wiley +1 more source
Characteristics of a new variant of rabbit haemorrhagic disease virus – RHDV2
Acta Biologica, 2019 RHD (Rabbit Haemorrhagic Disease) is an etiologic agent that causes viral haemorrhagic disease of rabbits, which is also referred to as rabbit plague. The desire to explore knowledge about this pathogen in the world results not only from its similarity ...
Dominika Bębnowska +1 more
doaj +1 more source
Advanced Science, EarlyView.FOXM1 maintains mitochondrial bioenergetic function by inhibiting MKRN1‐mediated ubiquitination of LKB1 in cardiomyocytes. Loss of FOXM1 in cardiomyocytes results in upregulation of MKRN1, which enhances LKB1 ubiquitination and disrupts AMPK signaling and energy metabolism pathways. Conversely, FOXM1 overexpression preserves mitochondrial bioenergetics
Shuai Song +17 more
wiley +1 more source
BMC Veterinary Research, 2020 Background Rabbit hemorrhagic disease virus (RHDV, Lagovirus europeus GI.1) induces a contagious and highly lethal hemorrhagic disease in rabbits. In 2010 a new genotype of lagovirus (GI.2), emerged in Europe, infecting wild and domestic population of ...
Melanie Buehler +7 more
doaj +1 more source
Microbiology Spectrum, 2023 Myxoma virus (MYXV) and rabbit hemorrhagic disease virus (RHDV) are important drivers of the population decline of the European rabbit, an endangered keystone species.
Joana Coelho +5 more
doaj +1 more source
Clinical Pathology Evaluation in Pet Rabbits Vaccinated Against Rabbit Hemorrhagic Disease Virus 2 (RHDV2). [PDF]
Animals (Basel)A recombinant vaccine for rabbit hemorrhagic disease virus 2, a highly pathogenic virus, was granted emergency use authorization in the United States after the detection and spread of the virus starting in 2018. The goal of the current study was to assess pet rabbits (n = 29) through physical examination and routine clinical pathology testing using ...
Griffin C +5 more
europepmc +4 more sources
Animal Models and Experimental Medicine, EarlyView.Abstract Background Intracerebral hemorrhage (ICH) remains a devastating neurological disorder with limited therapeutic options. Neural stem cell (NSC)‐based therapies have emerged as a potential regenerative approach, yet the molecular mechanisms regulating NSC behavior require further elucidation.
Wei Dai +7 more
wiley +1 more source
Atomic model of rabbit hemorrhagic disease virus by cryo-electron microscopy and crystallography. [PDF]
PLoS Pathogens, 2013 Rabbit hemorrhagic disease, first described in China in 1984, causes hemorrhagic necrosis of the liver. Its etiological agent, rabbit hemorrhagic disease virus (RHDV), belongs to the Lagovirus genus in the family Caliciviridae.
Xue Wang +12 more
doaj +1 more source
BMEMat, EarlyView.Efficient drug delivery to the posterior segment of the eye has long been a challenging issue due to the complex ocular barriers. The review focuses on the promise held by nanoplatforms for barrier penetration and the key mechanisms involved, also highlighting their advantages in achieving efficient drug delivery and superior treatment of PSEDs ...
Yifan Shen +7 more
wiley +1 more source
Real-Time PCR Confirms Infection with Lagovirus europaeus
Applied Sciences, 2021 Lagovirus europaeus GI.1/GI.2 is an etiological agent causing the highly dangerous rabbit hemorrhagic disease (RHD). Molecular research is the basic tool today that can help solve epidemic problems related to the expansion of pathogens in the world.
Dominika Bębnowska +2 more
doaj +1 more source