Results 81 to 90 of about 19,271 (214)

Current Status of Kidney Xenotransplantation in Basic Research

Organ Medicine, EarlyView.
Kidney xenotransplantation is a potential solution to the organ shortage for end‐stage kidney disease. This review systematically elaborates on the application advances of donor pig gene editing technologies, the molecular mechanisms and regulatory strategies of xenogeneic immune rejection, and the optimization approaches of immune compatibility ...
Yu Luo, Bingzhuo Liu, Weijie Lai
wiley   +1 more source

Neglected Spleen Transcriptional Profile Reveals Inflammatory Disorder Conferred by Rabbit Hemorrhagic Disease Virus 2 Infection

Viruses
Rabbit hemorrhagic disease (RHD) is an acute fatal disease caused by the rabbit hemorrhagic disease virus (RHDV). Since the first outbreaks of type 2 RHDV (RHDV2) in April 2020 in China, the persistence of this virus in the rabbit population has caused ...
Jifeng Yu, Yan Li, Lu Xiao, Jing Xie, Zhiqiang Guo, Yonggang Ye, Yi Lin, Ye Cao, Xuejing Wu, Congjian Mao, Xingyu Li, Meng Pan, Jianqiang Ye, Long Zhou, Jian Huang, Junyan Yang, Yong Wei, Xianhui Zhang, Bin Zhang, Runmin Kang   +19 more
doaj   +1 more source

Wild rabbit management in the Iberian Peninsula: state of the art and future perspectives for Iberian lynx conservation [PDF]

, 2017
The Iberian lynx, the most endangered cat in the world, is presently found only in two isolated populations in southern Spain. Natural expansion from these populations is limited which turns Iberian lynx reintroduction programs into the only alternative ...
Delibes-Mateos, Miguel, Ferreira, Catarina   +1 more
core   +1 more source

Sphinganine‐phosphate prevents influenza infection via promoting CD8+ T cells proliferation and activation

VIEW, EarlyView.
This study established clinical cohorts of respiratory viral infections and identified sphinganine‐phosphate (SA) as a metabolite significantly upregulated post‐infection through metabolomic analysis. In vitro and in vivo experiments demonstrated that SA promotes the generation of effector CD8+ T cells via the SOCS1/JAK1/STAT1 pathway, which ...
Zhongwen Hu, Guiling Yan, Junhong Li, Yuan Yuan, Hong Zhang, Yuchao Zhong, Yuanyuan Peng, Wenjia Zhang, Xiaoyan Su, Changchun Niu, Yang Luo   +10 more
wiley   +1 more source

Intracellular localization of Crimean-Congo Hemorrhagic Fever (CCHF) virus glycoproteins [PDF]

, 2005
Background Crimean-Congo Hemorrhagic Fever virus (CCHFV), a member of the genus Nairovirus, family Bunyaviridae, is a tick-borne pathogen causing severe disease in humans.
Fernando Lisa, Haferkamp Sebastian, Schwarz Tino F, Feldmann Heinz, Flick Ramon   +4 more
core   +2 more sources

Myeloablative Busulfan, Fludarabine and Melphalan Conditioning for Allogeneic Hematopoietic Stem Cell Transplantation in Childhood Myeloid Malignancy

Asia-Pacific Journal of Clinical Oncology, EarlyView.
We report our single‐center experience of transplant outcomes with a busulfan, fludarabine and melphalan‐based conditioning regimen for children < 18 years of age. The regimen was shown to be well tolerated and effective for heavily pretreated children with high‐risk myeloid malignancies prior to allogeneic hematopoietic stem cell transplant.
Mayank Dhamija, Fiona Kerr, Hazel Gough, Johnathan Soggee, Laurence C. Cheung, Rishi S. Kotecha, Shanti Ramachandran   +6 more
wiley   +1 more source

Evidence for human norovirus infection of dogs in the United kingdom. [PDF]

, 2015
Human noroviruses (HuNoVs) are a major cause of viral gastroenteritis, with an estimated 3 million cases per year in the United Kingdom. HuNoVs have recently been isolated from pet dogs in Europe (M. Summa, C.-H. von Bonsdorff, and L.
Belliot, Gael, Brownlie, Joe, Caddy, Sarah L, de Rougemont, Alexis, El-Attar, Laila, Emmott, Edward, Goodfellow, Ian, Hollinshead, Michael, Le Pendu, Jacques, Mitchell, Judy A   +9 more
core   +5 more sources

Comparative Phylodynamics of Rabbit Hemorrhagic Disease Virus in Australia and New Zealand [PDF]

Journal of Virology, 2015
ABSTRACTThe introduction of rabbit hemorrhagic disease virus (RHDV) into Australia and New Zealand during the 1990s as a means of controlling feral rabbits is an important case study in viral emergence. Both epidemics are exceptional in that the founder viruses share an origin and the timing of their release is known, providing a unique opportunity to ...
John-Sebastian, Eden, John, Kovaliski, Janine A, Duckworth, Grace, Swain, Jackie E, Mahar, Tanja, Strive, Edward C, Holmes   +6 more
openaire   +2 more sources

Air embolism secondary to suspected lymphatic tissue disruption with severe exercise‐induced pulmonary haemorrhage

Equine Veterinary Education, EarlyView.
Summary Air embolism is rare in horses and typically associated with complications following intravenous catheterisation or other medical procedures. Exercise‐induced pulmonary haemorrhage (EIPH) is common in racehorses but not usually associated with air embolism. This report describes a case of air embolism in a 4‐year‐old Thoroughbred with EIPH. The
J. Wittenberg, K. Drozdzewska, K. Landmann, A. Voß, K. Kunze, D. Rutenberg, A. D. Gruber, H. Gehlen   +7 more
wiley   +1 more source

Genetic characterization of interleukins (IL-1α, IL-1β, IL-2, IL-4, IL-8, IL-10, IL-12A, IL-12B, IL-15 and IL-18) with relevant biological roles in lagomorphs [PDF]

, 2015
Disponível em: www.ncbi.nlm.nih.gov/pmc/articles/pmid/26395994/ILs, as essential innate immune modulators, are involved in an array of biological processes.
Abrantes, J., Almeida, T., Costa, Paulo, de Matos, A.L., Esteves, P.J., Neves, F.   +5 more
core   +1 more source