Results 71 to 80 of about 20,265 (227)

Nanostructured drug delivery systems for posterior segment eye diseases: Strategies to defy ocular barriers

open access: yesBMEMat, EarlyView.
Efficient drug delivery to the posterior segment of the eye has long been a challenging issue due to the complex ocular barriers. The review focuses on the promise held by nanoplatforms for barrier penetration and the key mechanisms involved, also highlighting their advantages in achieving efficient drug delivery and superior treatment of PSEDs ...
Yifan Shen   +7 more
wiley   +1 more source

Wild rabbit management in the Iberian Peninsula: state of the art and future perspectives for Iberian lynx conservation [PDF]

open access: yes, 2017
The Iberian lynx, the most endangered cat in the world, is presently found only in two isolated populations in southern Spain. Natural expansion from these populations is limited which turns Iberian lynx reintroduction programs into the only alternative ...
Delibes-Mateos, Miguel   +1 more
core   +1 more source

Immunological Cross-Protection between Different Rabbit Hemorrhagic Disease Viruses—Implications for Rabbit Biocontrol and Vaccine Development

open access: yesVaccines, 2022
The use of rabbit hemorrhagic disease virus (RHDV) as a biocontrol agent to control feral rabbit populations in Australia, in combination with circulating endemic strains, provides a unique environment to observe the interactions between different ...
Tiffany W. O’Connor   +4 more
doaj   +1 more source

Cardiotrophin-1 promotes a high survival rate in rabbits with lethal fulminant hepatitis of viral origin [PDF]

open access: yes, 2011
Rabbit hemorrhagic disease virus (RHDV) causes lethal fulminant hepatitis closely resembling acute liver failure (ALF) in humans. In this study, we investigated whether cardiotrophin-1 (CT-1), a cytokine with hepatoprotective properties, could attenuate ...
Alvarez, M. (Marcelino)   +9 more
core   +2 more sources

Infection Risk From Humans and Animals in the Anatomy Laboratory: A Scoping Review

open access: yesClinical Anatomy, EarlyView.
ABSTRACT Whole‐body dissection is a cornerstone of anatomy education. During and following the COVID‐19 pandemic, exposure to infectious agents and other risks of dissection were highlighted. To identify potential risks, one must have the data outlining these risks in specific situations.
Margaret A. McNulty, Elizabeth R. Agosto
wiley   +1 more source

RNAi Inhibition of Rabbit Hemorrhagic Disease Virus (RHDV) Gene Expression in CHO Cell Line [PDF]

open access: yesمجلة جامعة النجاح للأبحاث العلوم الطبيعية, 2008
Rabbit hemorrhagic disease virus (RHDV) causes great losses and is life threatening to both wild and domestic rabbits. This work represents the first step toward production of transgenic rabbits resistant to RHDV by RNAi through the inhibition of ...
Bilal Ghareeb
doaj   +1 more source

PRMT5 Mediates Sepsis‐Associated Lung Injury by Modulating JAK1 Arginine Methylation: A Mechanism Study

open access: yesThe Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Lung injury is a common complication in critical sepsis. PRMT5 is implicated in endothelial inflammation and lung diseases, but its role in sepsis‐associated lung injury remains unclear. This study collected clinical sepsis samples and detected the mRNA expression of PRMT5.
Bo Wang, Zhen Ge, Fei‐Xiang Chen
wiley   +1 more source

Rabbit Hemorrhagic Disease Virus Variant Recombinant VP60 Protein Induces Protective Immunogenicity

open access: yesJournal of Microbiology and Biotechnology, 2015
Rabbit hemorrhagic disease virus (RHDV) is highly contagious and often causes fatal disease that affects both wild and domestic rabbits of the species Oryctolagus cuniculus. A highly pathogenic RHDV variant (RHDVa) has been circulation in the Korean rabbit population since 2007 and has a devastating effect on the rabbit industry in Korea.
Dong-Kun, Yang   +3 more
openaire   +2 more sources

Mouse Vocal Fold Permeability In Vivo: Effects of Novel Low‐Tech Injury and Instillation Methods

open access: yesThe Laryngoscope, EarlyView.
Improving experimental mouse vocal fold injury and instillation approaches is necessary to advance preclinical models of laryngeal disease. We have successfully repurposed low‐tech, quick, and reliable injury and instillation methods established in respiratory research. Using these methods, we show that murine vocal fold epithelium is inherently highly
Renee E. King   +2 more
wiley   +1 more source

Pulmonary vein aneurysm in a New Zealand White rabbit: a case report

open access: yesLaboratory Animal Research, 2022
Background Pulmonary venous aneurysm (PVA) is a rare condition characterized by aneurysmal dilatation of the pulmonary vein in humans. The diagnosis is incidental usually as there are no clinical symptoms.
Jong-Min Kim   +5 more
doaj   +1 more source

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