Results 71 to 80 of about 17,390 (200)
Disruption of Spike Priming in Virus Entry: Tetrandrine as a Pan‐Coronavirus Inhibitor
Tetrandrine inhibits the infection of HCoV‐OC43, HCoV‐229E, SARS‐CoV‐2, and its major variants by blocking virus entry. Specifically, tetrandrine breaks the interaction between TMPRSS2 and Spike, therefore suppress its priming and the following membrane fusion, and induces Spike to degradation.
Kun Wang +9 more
wiley +1 more source
Key features of Ebola hemorrhagic fever: a review
The current outbreak of Ebola virus in West Africa has become a devastating problem, with a mortality rate around 51%; over 3 132 deaths have been confirmed and even more are expected in this case.
Zulane Lima Sousa
doaj +1 more source
Interferometric detection and enumeration of viral particles using Si-based microfluidics [PDF]
Single-particle interferometric reflectance imaging sensor enables optical visualization and characterization of individual nanoparticles without any labels.
Kanik, Fulya Ekiz +4 more
core +1 more source
Abstract This study aims to identify different frontline emergency response workforce's perceived knowledge of hazards and their willingness and motivations to go to work during them. An online version of the “Fight or Flight” survey was distributed and collected from Norwegian emergency personnel during the spring of 2023.
Jarle L. Sørensen +9 more
wiley +1 more source
Diagnostic schemes for reducing epidemic size of african viral hemorrhagic fever outbreaks
Introduction: Viral hemorrhagic fever (VHF) outbreaks, with high mortality rates, have often been amplified in African health institutions due to person-to-person transmission via infected body fluids.
Iruka N Okeke +2 more
doaj +1 more source
Human neurotropic viruses like SARS‐CoV‐2, HSV, HOPV and RSV pose significant risks due to their ability to invade and persist in the nervous system. Stapled peptides represent a promising therapeutic approach with enhanced stability, target affinity and bioavailability, emerging as an effective strategy for neutralising human neurotropic viruses ...
Sanskruti Patil +4 more
wiley +1 more source
Ebola Hemorrhagic Fever as a Public Health Emergency of International Concern; a Review Article
Ebola hemorrhagic fever (EHF) was first reported in 1976 with two concurrent outbreaks of acute viral hemorrhagic fever centered in Yambuku (near the Ebola River), Democratic Republic of Congo, and also in Nzara, Sudan.
Saeed Safari +4 more
doaj
Molecular Mechanisms of Ebola Virus Entry into Permissive Cells
Ebola virus, representative of the Ebolavirus genus, Filoviridae family, causes severe hemorrhagic fever in humans, with lethality rates amounting up to 90 %. The members of Ebolavirus genus infect a broad range of mammalian cells.
T. E. Sizikova +3 more
doaj +1 more source
Macaque models of human infectious disease. [PDF]
Macaques have served as models for more than 70 human infectious diseases of diverse etiologies, including a multitude of agents-bacteria, viruses, fungi, parasites, prions.
Abe +330 more
core +1 more source
Pathogens causing transmissible viral hemorrhagic fevers are therefore classified internationally at the most dangerous hazard level. Most of them may be transmitted through the respiratory tract into human being. For this reason aerosol dissemination of viral pathogens may be considered as biological weapon.
openaire +1 more source

