Results 71 to 80 of about 17,282 (199)

Increasing Occurrence of Marburg Virus Outbreaks in Africa: Risk Assessment for Public Health

open access: yesMicrobial Biotechnology, Volume 18, Issue 9, September 2025.
Bat and Marburg virus (Filovirus). Left: A Rousettus aegyptiacus bat; Center: a distribution map of R. aegyptiacus; Right: EM of Marburg virus. (figure credits: Left Wikipedia Nilflughund Lithuanian Zoological Gardens, Center; Center: Wikipedia Nilflughund IUCN Red List of Threatened Species, right Wikipedia Marburg virus CDC Fred Murphy; J.
Harald Brüssow
wiley   +1 more source

Wave-like spread of Ebola Zaire [PDF]

open access: yes, 2005
In the past decade the Zaire strain of Ebola virus (ZEBOV) has emerged repeatedly into human populations in central Africa and caused massive die-offs of gorillas and chimpanzees.
Leslie A Real   +3 more
core   +5 more sources

Key features of Ebola hemorrhagic fever: a review

open access: yesAsian Pacific Journal of Tropical Biomedicine, 2014
The current outbreak of Ebola virus in West Africa has become a devastating problem, with a mortality rate around 51%; over 3 132 deaths have been confirmed and even more are expected in this case.
Zulane Lima Sousa
doaj   +1 more source

Inhibition of the Clathrin Terminal Domain—Amphiphysin Protein–Protein Interaction. Probing the Pitstop 2 Aromatic Moiety

open access: yesChemMedChem, Volume 20, Issue 16, August 16, 2025.
Pitstop 2 binds to the clathrin terminal domain. This work explores the nature of the benzylidene moiety, R. The synthesis of 56 novel analogues reveals enhanced potency of a multiple analogues, with catechol‐free 2,3‐dihydroxybenzo[b][1,4]dioxone (54) returning a 1.2 μm IC50, ca 10‐fold more active than Pitstop 2. Pitstop 2, (Z)‐N‐(5‐(4‐bromenzylidene)
Kate Prichard   +10 more
wiley   +1 more source

Diagnostic schemes for reducing epidemic size of african viral hemorrhagic fever outbreaks

open access: yesJournal of Infection in Developing Countries, 2014
Introduction: Viral hemorrhagic fever (VHF) outbreaks, with high mortality rates, have often been amplified in African health institutions due to person-to-person transmission via infected body fluids.
Iruka N Okeke   +2 more
doaj   +1 more source

Ebola Hemorrhagic Fever as a Public Health Emergency of International Concern; a Review Article

open access: yesEmergency, 2015
Ebola hemorrhagic fever (EHF) was first reported in 1976 with two concurrent outbreaks of acute viral hemorrhagic fever centered in Yambuku (near the Ebola River), Democratic Republic of Congo, and also in Nzara, Sudan.
Saeed Safari   +4 more
doaj  

Molecular Mechanisms of Ebola Virus Entry into Permissive Cells

open access: yesПроблемы особо опасных инфекций, 2015
Ebola virus, representative of the Ebolavirus genus, Filoviridae family, causes severe hemorrhagic fever in humans, with lethality rates amounting up to 90 %. The members of Ebolavirus genus infect a broad range of mammalian cells.
T. E. Sizikova   +3 more
doaj   +1 more source

The Antiviral Activity of Polyphenols

open access: yesMolecular Nutrition &Food Research, Volume 69, Issue 15, August 2025.
Polyphenols demonstrate remarkable antiviral properties by effectively disrupting multiple biochemical processes essential for viral replication. ABSTRACT Polyphenols are secondary metabolites produced by a large variety of plants. These compounds that comprise the class of phenolic acids, stilbenes, lignans, coumarins, flavonoids, and tannins have a ...
Markus Burkard   +5 more
wiley   +1 more source

Ebola viral hemorrhagic fever

open access: yesJournal of Health Policy & Outcomes Research, 2014
Pathogens causing transmissible viral hemorrhagic fevers are therefore classified internationally at the most dangerous hazard level. Most of them may be transmitted through the respiratory tract into human being. For this reason aerosol dissemination of viral pathogens may be considered as biological weapon.
openaire   +1 more source

Macaque models of human infectious disease. [PDF]

open access: yes, 2008
Macaques have served as models for more than 70 human infectious diseases of diverse etiologies, including a multitude of agents-bacteria, viruses, fungi, parasites, prions.
Abe   +330 more
core   +1 more source

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