Results 61 to 70 of about 74,869 (261)

Viral hemorrhagic fevers - a recurrent public health threat

Health Problems of Civilization, 2021
Viral hemorrhagic fevers (VHFs) caused by viruses are severe infectious diseases that lead to serious disturbances of the body’s homeostasis, in most cases accompanied by symptoms of hemorrhagic diathesis.
Marcin Weiner, Karolina Tarasiuk
doaj   +1 more source

Nosocomial outbreak of novel arenavirus infection, Southern Africa [PDF]

, 2009
A nosocomial outbreak of disease involving 5 patients, 4 of whom died, occurred in South Africa during September—October 2008. The first patient had been transferred from Zambia to South Africa for medical management.
, Asomugha, Chika, Blumberg, Lucille H., Briese, Thomas, Ching, Pamela, Cohen, Cheryl, de Jong, Gillian, Dinh, Thu-Ha, Duse, Adriano, Hale, Martin J., Ikalafeng, Bridget, Ksiazek, Thomas G., Lipkin, W. Ian, Malotle, Mirriam M., McMullan, Laura K., Misiani, Eunice, Mnyaluza, Joy, Mugero, Charles, Mukonka, Victor, Nichol, Stuart T., Nteo, Dorothy M., Paddock, Christopher D., Paweska, Janusz T., Richards, Guy, Rollin, Pierre E., Sewlall, Nivesh H., Swanepoel, Robert, Teams, Investigation, Weyer, Jacqueline, Zaki, Sherif R.   +29 more
core   +3 more sources

Compendium: Management of Viral Hemorrhagic Fever (Viral Fever), Involving Its Pathogenesis

Asian Journal of Research in Infectious Diseases
The term "Viral Hemorrhagic Fever" (VHF) describes a severe feverish sickness characterized by aberrant vascular control, vascular damage, and hemorrhagic symptoms. Multiple viruses belonging to distinct families are the cause of this illness.
Yash Srivastav, Aniket Kumar, Jaya Singh, Aditya Srivastav, Mohd. Imtiyaz Ahmad   +4 more
semanticscholar   +1 more source

Serological Assays Based on Recombinant Viral Proteins for the Diagnosis of Arenavirus Hemorrhagic Fevers

Viruses, 2012
The family Arenaviridae, genus Arenavirus, consists of two phylogenetically independent groups: Old World (OW) and New World (NW) complexes. The Lassa and Lujo viruses in the OW complex and the Guanarito, Junin, Machupo, Sabia, and Chapare viruses in the
S. Fukushi, H. Tani, T. Yoshikawa, M. Saijo, S. Morikawa   +4 more
semanticscholar   +1 more source

Viral Hemorrhagic Fever Preparedness

, 2017
The 2014–2016 outbreak of Ebola virus disease (EVD) in West Africa marked the 25th such occurrence but was noteworthy in its massive scope, causing more human morbidity and mortality than the previous 24 recorded outbreaks combined. As of April 2016, there were 28,652 cases resulting in at least 11,325 deaths, nearly all in the three nations of Guinea,
Theodore J. Cieslak, Shelly Schwedhelm, Angela Vasa, John J. Lowe, John J. Lowe, Angela L. Hewlett   +5 more
openaire   +2 more sources

Oropouche virus: clinical, epidemiological, and molecular aspects of a neglected orthobunyavirus. [PDF]

, 2017
Oropouche virus (OROV) is an important cause of arboviral illness in Latin American countries, more specifically in the Amazon region of Brazil, Venezuela and Peru, as well as in other countries such as Panama.
Acrani, Gustavo Olszanski, Cardoso, Jedson Ferreira, da Rosa, Jorge Fernando Travassos, de Paula Pinheiro, Francisco, de Souza, William Marciel, Figueiredo, Mário Luiz, Nunes, Márcio Roberto Teixeira   +6 more
core   +1 more source

Inhibition of the clathrin terminal domain – amphiphysin protein‐protein interaction. Probing the Pitstop® 2 aromatic moiety.

ChemMedChem, Accepted Article.
Pitstop 2, (Z)‐N‐(5‐(4‐bromenzylidene)‐4‐oxo‐4,5‐dihydrothiazol‐2‐yl)naphthalene‐1‐sulfonamide (1), inhibits the clathrin terminal domain‐ amphiphysin interaction (NTD‐PPI) and has been widely used to investigate endocytosis. In this work we report on the synthesis of 56 novel Pitstop 2 analogues via four discrete focused libraries.
Kate Prichard, Mark J Robertson, Ngoc Chau, Jing Xue, Martin Neuenschwander, Uwe Fink, Andre Horatscheck, Marc Nazare, Phillip J Robinson, Volker Haucke, Adam McCluskey   +10 more
wiley   +1 more source

Antibody-based inhibition of pathogenic new world hemorrhagic fever mammarenaviruses by steric occlusion of the human transferrin receptor 1 apical domain [PDF]

, 2021
Pathogenic clade B New World mammarenaviruses (NWM) can cause Argentine, Venezuelan, Brazilian, and Bolivian hemorrhagic fevers. Sequence variability among NWM glycoproteins (GP) poses a challenge to the development of broadly neutralizing therapeutics ...
Abraham, Jonathan, Batto, María V., Clark, Lars E., Collazo, Michael, Cordo, Sandra Myriam, Ferrero, Sol, Flores, Maria D., Fuentes, Daniel, García, Cybele C., Helguera, Gustavo Fernando, Payés, Cristian, Rodriguez, Jose A., Short, Connor, Vázquez, Cecilia Alejandra, Ziegenbein, James, Zink, Samantha   +15 more
core   +1 more source

Use of the Syrian Hamster as a New Model of Ebola Virus Disease and Other Viral Hemorrhagic Fevers

Viruses, 2012
Historically, mice and guinea pigs have been the rodent models of choice for therapeutic and prophylactic countermeasure testing against Ebola virus disease (EVD). Recently, hamsters have emerged as a novel animal model for the in vivo study of EVD.
V. Wahl-Jensen, Laura Bollinger, D. Safronetz, Fabian de Kok-Mercado, D. Scott, H. Ebihara   +5 more
semanticscholar   +1 more source

FIGO guideline on liver disease and pregnancy

International Journal of Gynecology &Obstetrics, EarlyView.
Abstract The number of women entering pregnancy with chronic liver disease is rising. Gestational liver disorders affect 3% of the pregnant population. Both can be associated with significant maternal and fetal morbidity and mortality. European guidance has recently been published to inform management.
Melanie Nana, Virna Medina, Cynthia Maxwell, Ciara McCormick, Gloria Taliani, Ulrich Beuers, Deborah Money, Bo Jacobsson, Anil Kapur, Titus Beyuo, Francisco Ruiloba, Graeme Smith, Lina Bergman, Sharleen O'Reilly, Patrick O'Brien, Mark Hanson, Mary Rosser, Claudio Sosa, Sumaiya Adam, Valerie Guinto, Liona Poon, Fionnuala McAuliffe, Catherine Williamson, on behalf of the FIGO Committee on Impact of Pregnancy on Long‐term Health, FIGO Committee on Infections during Pregnancy and the FIGO Division of Maternal and Newborn Health   +24 more
wiley   +1 more source