Results 71 to 80 of about 6,534 (214)

Feasibility and Safety of Venetoclax for Cytoreduction During Induction Therapy in Newly Diagnosed Acute Promyelocytic Leukemia

European Journal of Haematology, EarlyView.
ABSTRACT Objective This study aimed to evaluate the feasibility and safety of venetoclax as a cytoreductive strategy during induction therapy in newly diagnosed acute promyelocytic leukemia (APL), and to provide an exploratory description of its early efficacy.
Yu Wang, Rong Xiao, Xiaobing Huang, Yi Xiao   +3 more
wiley   +1 more source

Italian Patients Journey for Gene Therapy in Haemophilia A

Haemophilia, EarlyView.
ABSTRACT Introduction Gene therapy (GT) provides sustained FVIII levels without repeated infusions in Hemophilia A (HA) patients thus overcoming a major limitation of replacement therapy. However, issues remain e.g., patient selection criteria, duration and variability of transgene expression, quality of life and long‐term safety.
Giovanni Di Minno, Gaia Spadarella, Alessandra Borchiellini, Anna Borrelli, Andrea Buzzi, Giancarlo Castaman, Michele Cecchi, Raimondo De Cristofaro, Vincenzo La Mura, Angelo Lupi, Giuseppe Malcangi, Maria Elisa Mancuso, Maria Francesca Mansueto, Cristina Santoro, Rita Carlotta Santoro, Luigi Piero Solimeno, Annarita Tagliaferri, Ezio Zanon, Isabella Garagiola, Flora Peyvandi   +19 more
wiley   +1 more source

Beyond the Kidney and Lung: Cutaneous and Mucosal Clues to Human Hantavirus Disease

International Journal of Dermatology, EarlyView.
Rodent exposure and aerosolized excreta can lead to hantavirus infection with systemic endothelial injury and capillary leak, resulting in thrombocytopenia and syndromes such as HPS/HCPS and HFRS/NE. Early dermatologic and mucosal findings, including flushing, conjunctival injection, petechiae/purpura, and mucosal bleeding, may provide important clues ...
Giuseppe Gallo, Pietro Quaglino, Simone Ribero   +2 more
wiley   +1 more source

Management of Non‐Plaque‐Induced Gingival Conditions: A Systematic Review—Part 2: Inflammatory and Immune Conditions; Neoplasms; and Gingival Pigmentation

Journal of Clinical Periodontology, EarlyView.
ABSTRACT Aims This systematic review assesses current evidence on the management of non‐plaque (dental biofilm)‐induced gingival diseases and conditions (NPIGDs), including (i) inflammatory and immune conditions, (ii) neoplasms and (iii) gingival pigmentations.
Maria Clotilde Carra, Cecile Wasielewski, Bruno Špiljak, Maja Sabalić‐Schoener, Sebastien Jungo, Ivan Alajbeg   +5 more
wiley   +1 more source

Health Screening and Post‐Arrival Services for Refugee Children From Afghanistan

Journal of Paediatrics and Child Health, EarlyView.
ABSTRACT Aim To examine refugee health screening and services for Afghan children in the unique context of emergency expedited humanitarian resettlement in Melbourne, Australia. Methods Retrospective audit of Afghan children who attended a specialist child refugee health service between August 2021–April 2024. Results Participants included 218 children
Amy Williamson, Eva Sudbury, Rija Khanal, Jade Woon, Jennifer Schaefer, Georgia Paxton   +5 more
wiley   +1 more source

Natural infection of Aedes albopictus with the wAlbB strain and Ae. aegypti with the wPip strain of Wolbachia in Iran

Scientific Reports
The global resurgence of Aedes-borne arboviruses (dengue, chikungunya, and Zika) underscores the need for innovative vector control strategies. In Iran—a region at risk for arbovirus emergence due to invasive Aedes albopictus and Ae.
Fateh Karimian, Sara Rahimy, Hemn Yousefi, Mostafa Salehi-Vaziri, Abbasali Raz, Mohammad Hassan Pouriayevali, Eslam Moradi-Asl, Naseh Maleki-Ravasan   +7 more
doaj   +1 more source

Management of Kaposiform Haemangioendothelioma—A Retrospective Case Series Examining the Use and Effectiveness of Vincristine

Journal of Paediatrics and Child Health, EarlyView.
ABSTRACT Aim Kaposiform haemangioendothelioma is a rare vascular tumour. Management has evolved over the last two decades, with most cases receiving vincristine or sirolimus. We aim to describe our experience with managing this tumour, with a focus on the safety and efficacy of vincristine.
Bronwen Kirk, Susan Adams, Orli Wargon, Artiene Tatian, Susan Russell   +4 more
wiley   +1 more source

Oral Health, Periodontitis, and Respiratory Diseases: Biological Pathways

Journal of Periodontal Research, EarlyView.
This narrative review aims to provide a comprehensive update on the potential mechanisms by which poor oral health and periodontitis impact lung health, focusing on pneumonia, COPD, and asthma. ABSTRACT Poor oral hygiene and periodontitis influence lung diseases such as pneumonia, chronic obstructive pulmonary disease (COPD), COVID‐19, and asthma.
Raluca P. Vacaru, Andreea C. Didilescu, Frank A. Scannapieco   +2 more
wiley   +1 more source

Anaemia Among Mother–Child Dyads in India: Trends, Drivers, and Future Projections

Maternal &Child Nutrition, EarlyView.
ABSTRACT Anaemia among mothers and their children is a widespread public health challenge with profound consequences for individuals and societies. While anaemia has been studied separately in women and children, there remains a literature gap examining anaemia in mother‐child dyads, limiting insights on interventions that may simultaneously address ...
Sarang Pedgaonker, Trupti Meher, Monali Gupta, Suman Chakrabarti, Phuong Hong Nguyen, Shri Kant Singh, Laxmi Kant Dwivedi, Aditi, Samuel Scott   +8 more
wiley   +1 more source

The low genetic diversity of the Jingmen tick virus in Guinea sheds light on the recent introduction of the virus to West Africa

Parasites & Vectors
Background Jingmen tick virus (JMTV), a segmented orthoflavi-like virus, has been recognized in recent years as a potential human and animal pathogen, with confirmed detections across Asia, Europe, Africa and South America.
Marat T. Makenov, Sanaba Boumbaly, Tatiana A. Bondarenko, Daria D. Skripnichenko, Namoudou Conde, Noumany Sacko, Faya Raphael Tolno, Mory Sangare, Ivan S. Kholodilov, Dmitriy V. Dubrovskiy, Mamadou Gando Diallo, Oxana A. Belova, Bonaventure Kolie, Kseniia A. Sycheva, Anna S. Kalyanova, Leno Tamba N’Fatoma, Alimou Camara, Vasily G. Akimkin, Evgeny S. Morozkin   +18 more
doaj   +1 more source