Results 21 to 30 of about 4,142 (152)
mBio, 2022 Defective interfering particles (DIs) contain a considerably smaller genome than the parental virus but retain replication competency. As DIs can directly or indirectly alter propagation kinetics of the parental virus, they offer a novel approach to ...
Stephen R. Welch +9 more
doaj +1 more source
Targeted Strategies for Henipavirus Therapeutics [PDF]
The Open Virology Journal, 2007 Hendra and Nipah viruses are related emergent paramyxoviruses that infect and cause disease in animals and humans. Disease manifests as a generalized vasculitis affecting multiple organs, but is the most severe in the respiratory and central nervous systems.
Bossart, Katharine N +2 more
openaire +2 more sources
Identifying Suspect Bat Reservoirs of Emerging Infections
Vaccines, 2020 Bats host a number of pathogens that cause severe disease and onward transmission in humans and domestic animals. Some of these pathogens, including henipaviruses and filoviruses, are considered a concern for future pandemics.
Daniel Crowley +3 more
doaj +1 more source
Antibodies to henipavirus or henipa-like viruses in domestic pigs in Ghana, West Africa.
PLoS ONE, 2011 Henipaviruses, Hendra virus (HeV) and Nipah virus (NiV), have Pteropid bats as their known natural reservoirs. Antibodies against henipaviruses have been found in Eidolon helvum, an old world fruit bat species, and henipavirus-like nucleic acid has been ...
David T S Hayman +7 more
doaj +1 more source
Henipavirus sero-surveillance in horses and pigs from Northern Nigeria
Frontiers in Virology, 2022 Hendra virus and Nipah virus are considered to be emerging viruses and cause severe zoonotic diseases, which occur in humans who have had close contact with horses and pigs in Australia and Asia, respectively. Both viruses belong to the genus Henipavirus.
Andrew Musa Adamu +11 more
doaj +1 more source
Development of a Porcine Cell Line Stably Expressing Ephrin-B2 for Nipah Virus Research and Diagnostic Testing. [PDF]
Microbiol ImmunolABSTRACT Nipah virus (NiV) is a highly pathogenic zoonotic virus transmitted from bats to humans through pigs as a crucial intermediate host. NiV outbreaks pose significant public health and economic threats, especially for pig farmers. Although the World Organization for Animal Health recommends African green monkey‐derived Vero cells for NiV ...
Zhang H, Saito A.
europepmc +2 more sources
Henipavirus Mediated Membrane Fusion, Virus Entry and Targeted Therapeutics
Viruses, 2012 The Paramyxoviridae genus Henipavirus is presently represented by the type species Hendra and Nipah viruses which are both recently emerged zoonotic viral pathogens responsible for repeated outbreaks associated with high morbidity and mortality in ...
Dimitar B. Nikolov +3 more
doaj +1 more source
PLoS Pathogens, 2016 Hendra and Nipah viruses (genus Henipavirus, family Paramyxoviridae) are highly pathogenic bat-borne viruses. The need for high biocontainment when studying henipaviruses has hindered the development of therapeutics and knowledge of the viral infection ...
Celine Deffrasnes +14 more
doaj +1 more source
A conserved motif in Henipavirus P/V/W proteins drives the fibrillation of the W protein from Hendra virus. [PDF]
Protein SciAbstract The Hendra (HeV) and Nipah (NiV) viruses are high‐priority, biosafety level‐4 pathogens that cause fatal neurological and respiratory disease. Their P gene encodes not only the P protein, an essential polymerase cofactor, but also the virulence factors V and W.
Gondelaud F +4 more
europepmc +2 more sources
Henipavirus Receptor Usage and Tropism [PDF]
, 2012 Nipah (NiV) and Hendra (HeV) viruses are the deadliest human pathogens within the Paramyxoviridae family, which include human and animal pathogens of global biomedical importance. NiV and HeV infections cause respiratory and encephalitic illness with high mortality rates in humans.
Olivier, Pernet +2 more
openaire +2 more sources