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Cedar virus biology and its applications as a surrogate for highly pathogenic henipaviruses
Nipah Virus (NiV) and Hendra Virus (HeV), are the prototype species of the genus Henipavirus and are highly pathogenic agents capable of causing fatal diseases in both animals and humans.
Ahmad Jawad Sabir +3 more
doaj +1 more source
Genome Sequence Conservation of Hendra Virus Isolates during Spillover to Horses, Australia
Bat-to-horse transmission of Hendra virus has occurred at least 14 times. Although clinical signs in horses have differed, genome sequencing has demonstrated little variation among the isolates.
Glenn A. Marsh +11 more
doaj +1 more source
Henipavirus Infections: Lessons from Animal Models [PDF]
The Henipavirus genus contains two highly lethal viruses, the Hendra and Nipah viruses and one, recently discovered, apparently nonpathogenic member; Cedar virus. These three, negative-sense single-stranded RNA viruses, are hosted by fruit bats and use EphrinB2 receptors for entry into cells.
Dhondt, Kévin P., Horvat, Branka
openaire +4 more sources
Distinct Cell Transcriptomic Landscapes Upon Henipavirus Infections [PDF]
Hendra virus (HeV) and Cedar virus (CedV) are henipaviruses, which fall into the Paramyxoviridae family of single-stranded, negative-sense RNA viruses. HeV is classified as a Biosafety Level-4 (BSL-4) agent, as it is highly pathogenic and is often fatal to humans. To date, no HeV prevention or treatment methods for human are available.
Mingyue Chen +8 more
openaire +3 more sources
Heparan Sulfate-Dependent Enhancement of Henipavirus Infection [PDF]
ABSTRACT Nipah virus and Hendra virus are emerging, highly pathogenic, zoonotic paramyxoviruses that belong to the genus Henipavirus . They infect humans as well as numerous mammalian species. Both viruses use ephrin-B2 and -B3 as cell entry receptors, and following initial entry into an organism, they are
Mathieu, Cyrille +9 more
openaire +4 more sources
Nipah virus (NiV) and Hendra virus (HeV) are classified as high-consequence zoonotic viruses characterized by high pathogenicity and high mortality in animals and humans. Rapid diagnosis is essential to containing the outbreak.
Ming Yang +6 more
doaj +1 more source
Henipavirus Vaccine Development
The henipaviruses, Hendra virus and Nipah virus, belong to the family Paramyxoviridae which has long been a source of highly contagious pathogens for both humans and animals. Some notable paramyxoviruses such as measles virus have spilled over from animals into humans to cause significant morbidity and mortality.
Jackie Pallister +2 more
openaire +1 more source
A Functional
Background Hendra virus (HeV) and Nipah virus (NiV) are newly emerged zoonotic paramyxoviruses discovered during outbreaks in Queensland, Australia in 1994 and peninsular Malaysia in 1998/9 respectively and classified within the new Henipavirus genus ...
Broder Christopher C, Khetawat Dimple
doaj +1 more source
Henipavirus Pathogenesis in Human Respiratory Epithelial Cells [PDF]
ABSTRACT Hendra virus (HeV) and Nipah virus (NiV) are deadly zoonotic viruses for which no vaccines or therapeutics are licensed for human use. Henipavirus infection causes severe respiratory illness and encephalitis. Although the exact route of transmission in human is unknown, epidemiological studies and in vivo
Olivier, Escaffre +6 more
openaire +2 more sources
Analysis of 57 536 high‐throughput sequencing datasets uncovers a vast, hidden world of viruses in wildlife. The researchers reveal significant geographic and host‐specific patterns of viruses, and their surprising cross‐species transmissions, such as avian flu viruses infecting goats.
Hai Wang +19 more
wiley +1 more source

