Results 91 to 100 of about 4,648 (202)

Robustness promotes evolvability of thermotolerance in an RNA virus [PDF]

, 2008
Background The ability for an evolving population to adapt to a novel environment is achieved through a balance of robustness and evolvability. Robustness is the invariance of phenotype in the face of perturbation and evolvability is the capacity to ...
Turner Paul E, Ogbunugafor C Brandon, McBride Robert C   +2 more
core   +2 more sources

In Silico Design and Characterization of a Multiepitope Vaccine Candidate Against Brucella canis Using a Reverse Vaccinology Approach

Journal of Immunology Research, Volume 2025, Issue 1, 2025.
Brucella canis is a Gram‐negative bacterium that causes canine brucellosis, a zoonotic disease with serious implications for public health and the global economy. Currently, there is no effective preventive vaccine for B. canis. Control measures include diagnostic testing, isolation, and euthanasia of infected animals.
Vicente Arriagada, Alberto Osorio, Crisleri Carrera-Naipil, Carlos A. Villacis-Aguirre, Cristian Escobar, Nicolás Morales, Danthe Villa, Lien Mardones, Dafne Pérez, Macarena Jara, Raúl E. Molina, Ítalo Ferrari, Sebastián Azocar, Leonardo A. Gómez, Ángel A. Oñate, Baohui Xu   +15 more
wiley   +1 more source

Nipah virus dynamics in bats and implications for spillover to humans. [PDF]

, 2020
Nipah virus (NiV) is an emerging bat-borne zoonotic virus that causes near-annual outbreaks of fatal encephalitis in South Asia-one of the most populous regions on Earth.
Ali Khan, Shahneaz, Anthony, Simon, Balkey, Maria, Briese, Thomas, Broder, Christopher, Crameri, Gary, Daszak, Peter, Epstein, Jonathan, Field, Hume, Fielder, Mark, Gurley, Emily, Hossein, M, Islam, Ariful, Islam, Ausraful, Khan, M, Kilpatrick, A, Lipkin, W, Luby, Stephen, Olival, Kevin, Quan, Phenix, Rahman, Mahmudur, Ross, Noam, Smith, Ina, Tao, Yun, Wang, Lin-Fa, Zambrana-Torrelio, Carlos   +25 more
core   +1 more source

Emergence of a Novel Canine Distemper Virus Variant in Urbanized Free‐Ranging Marmosets (Callithrix penicillata)

Transboundary and Emerging Diseases, Volume 2025, Issue 1, 2025.
The black‐tufted marmoset (Callithrix penicillata), commonly found in urban areas of Central Brazil, is vulnerable to pathogen spillover from domestic animals and humans. Here, we report an outbreak of natural canine distemper virus (CDV) infection among urbanized free‐ranging black‐tufted marmosets.
Tais Meziara Wilson, Davi Emanuel Ribeiro de Sousa, Isabel L. Macêdo, Mizael Machado, Gabriela Rodrigues de Toledo Costa, Pamela Fair, Jana M. Ritter, Hannah A. Bullock, Marlene DeLeon-Carnes, Elizabeth Lee, Pedro Henrique de Oliveira Passos, Daniel Garkauskas Ramos, Alessandro Pecego Martins Romano, Sandro Patroca da Silva, Livia Medeiros Nevs Casseb, Livia Caricio Martins, Luis Janssen Maia, Bergmann Morais Ribeiro, Eduardo Mauricio Mendes de Lima, Cristiano Barros de Melo, Márcio Botelho de Castro, Fabian Lean   +21 more
wiley   +1 more source

Multi-platform omics analysis of Nipah virus infection reveals viral glycoprotein modulation of mitochondria

Cell Reports
Summary: The recent global pandemic illustrates the importance of understanding the host cellular infection processes of emerging zoonotic viruses. Nipah virus (NiV) is a deadly zoonotic biosafety level 4 encephalitic and respiratory paramyxovirus.
Gunner P. Johnston, Fikret Aydemir, Haewon Byun, Emmie de Wit, Kristie L. Oxford, Jennifer E. Kyle, Jason E. McDermott, Brooke L. Deatherage Kaiser, Cameron P. Casey, Karl K. Weitz, Heather M. Olson, Kelly G. Stratton, Natalie C. Heller, Viraj Upadhye, I. Abrrey Monreal, J. Lizbeth Reyes Zamora, Lei Wu, D.H. Goodall, David W. Buchholz, Joeva J. Barrow, Katrina M. Waters, Ruth N. Collins, Heinz Feldmann, Joshua N. Adkins, Hector C. Aguilar   +24 more
doaj   +1 more source

Wildlife Pathogens and Zoonotic Disease Risk Assessment in Vietnam: A Wildlife Trade Hotspot

Transboundary and Emerging Diseases, Volume 2025, Issue 1, 2025.
Vietnam is a wildlife trade hotspot presenting multiple high‐risk interfaces for pathogen spillover from wildlife to humans. However, the zoonotic disease risk remains poorly characterized in the country and needs to be assessed to better inform policy dialog and legislative reforms.
Alice Latinne, Pawin Padungtod, Fedor Korennoy   +2 more
wiley   +1 more source

LANGYA: A NEW HENIPAVIRUS IN CHINA [PDF]

, 2022
China once again has a new virus outbreak which may be a Global health issue. First case of LayV) in human was reported on 8 August 2022, total 35 cases were reported. This may be a global health issue as like Covid 19.
CHAVAN, GITANJALI, SAKHARE, VISHAL, SHIRSAT, MRUNAL   +2 more
core   +1 more source

Bat‐Borne RNA Viruses: Addressing the Rising Health Risks in Bangladesh

Public Health Challenges, Volume 4, Issue 2, June 2025.
Md Nasir Ahmed
wiley   +1 more source

Risk Evaluation and Mitigation Strategies for Potential Outbreaks of Nipah Virus Infection: Evidenced by the Recent Incidences in Southeast Asian Countries

Health Science Reports, Volume 7, Issue 12, December 2024.
ABSTRACT Background The importance of studying Nipah virus (NiV) stems from its high fatality rates and potential for causing widespread outbreaks. Recent incidences in Southeast Asian countries highlight the urgent need for effective risk evaluation and mitigation strategies.
Md. Ashrafur Rahman, Yeasna Shanjana, Sydney Cronmiller, Donovan Zong, Rob Davis, Julianne Ernest, Jonah Nguyen, Amanda Rawa, Marie Roke Thomas, Md. Rabiul Islam   +9 more
wiley   +1 more source

Unraveling the Convoluted Biological Roles of Type I Interferons in Infection and Immunity: A Way Forward for Therapeutics and Vaccine Design

, 2016
It has been well-established that type I interferons (IFN-Is) have pleiotropic effects and play an early central role in the control of many acute viral infections.
Ranasinghe, Charani, Wijesundara, Danushka Kumara, Xi, Yang   +2 more
core   +1 more source