Results 81 to 90 of about 4,648 (202)

A novel Coltivirus-related virus isolated from free-tailed bats from Côte d’Ivoire is able to infect human cells in vitro [PDF]

, 2017
Background: Zoonotic transmission events play a major role in the emergence of novel diseases. While such events are virtually impossible to predict, wildlife screening for potential emerging pathogens can be a first step.
Dabrowski, Piotr Wojtek, Kurth, Andreas, Leendertz, Fabian H., Leendertz, Siv Aina J., Weiss, Sabrina   +4 more
core   +2 more sources

Unraveling the molecular grammar and the structural transitions underlying the fibrillation of a viral fibrillogenic domain

Protein Science, Volume 34, Issue 3, March 2025.
Abstract Hendra virus (HeV) is a biosafety level 4 human pathogen belonging to the Henipavirus genus within the Paramyxoviridae family. In HeV, the phosphoprotein‐encoding gene also drives the synthesis of the V and W proteins that are two major players in the host innate immune response evasion.
Frank Gondelaud, Julien Leval, Lisha Arora, Anuja Walimbe, Christophe Bignon, Denis Ptchelkine, Stefania Brocca, Samrat Mukhopadyay, Sonia Longhi   +8 more
wiley   +1 more source

Interferon Production and Signaling Pathways Are Antagonized during Henipavirus Infection of Fruit Bat Cell Lines

PLoS ONE, 2011
Bats are natural reservoirs for a spectrum of infectious zoonotic diseases including the recently emerged henipaviruses (Hendra and Nipah viruses). Henipaviruses have been observed both naturally and experimentally to cause serious and often fatal disease in many different mammal species, including humans.
Virtue E.R., Marsh G.A., Baker M.L., Wang L.-F.   +3 more
openaire   +6 more sources

In silico Drug Discovery of Novel Small Lead Compounds Targeting Nipah Virus Attachment Glycoprotein

Journal of Integrated Health Sciences, 2018
Introduction: Nipah virus (NiV) and Hendra virus are the type species of the highly pathogenic paramyxovirus genus Henipavirus, which can cause severe respiratory disease and fatal encephalitis infections in humans.
Ashish P. Shah, Bhumika M. Parmar, Mubasarin A. Ghodawala, Avinashkumar Seth   +3 more
doaj   +1 more source

Forêts tropicales, changements d'usage des sols et risques infectieux émergents [PDF]

, 2018
Les forêts intertropicales constituent une source exceptionnelle de diversité biologique spécifique en macro-organismes, mais elles se révèlent être aussi de véritables pépinières en micro-organismes. Ces cinquante dernières années, certains de ces micro-
Ayouba, Ahidjo, Cappelle, Julien, De Thoisy, Benoit, Guégan, Jean-François   +3 more
core   +5 more sources

Emerging Nipah Virus With Pandemic Potential and High Mortality Rates: Is the Scientific Community Learning From Former Pandemics?

Reviews in Medical Virology, Volume 35, Issue 2, March 2025.
ABSTRACT As Nipah virus (NiV) infection is characterised by a possible pandemic risk, being currently limited to a small but deadly belt, the attention of other countries is essential. It has often been pointed out that NiV is an under‐researched virus with a high‐risk potential. This study aimed to show the global research history and status quo based
Doris Klingelhöfer, Markus Braun, Christina A. Naser, Dörthe Brüggmann, David A. Groneberg   +4 more
wiley   +1 more source

Dissecting Henipavirus W proteins conformational and fibrillation properties: contribution of their N‐ and C‐terminal constituent domains

The FEBS Journal, Volume 292, Issue 3, Page 556-581, February 2025.
The W proteins of Nipah and Hendra viruses exhibit fibrillation abilities in vitro, which have been attributed to the intrinsically disordered N‐terminal domain (NTD). Our research shows that the C‐terminal domain (CTD) of both viruses is intrinsically disordered and non‐fibrillogenic.
Giulia Pesce, Frank Gondelaud, Denis Ptchelkine, Christophe Bignon, Patrick Fourquet, Sonia Longhi   +5 more
wiley   +1 more source

Chiroptera as a Potential Reservoir of Dangerous for Humans Viruses in the territory of the Republic of Guinea. Part 1

Проблемы особо опасных инфекций, 2018
Chiroptera is one of the largest in numbers orders of mammals which can take on the role of natural host and vector of various viruses, bacteria, and pathogenic fungi.
A. M. Porshakov, Yu. V. Kononova, V. B. Loktev, M. I. Boiro   +3 more
doaj   +1 more source

Quantifying Global Drivers of Zoonotic Bat Viruses: A Process-based Perspective [PDF]

, 2015
Emerging infectious diseases (EIDs), particularly zoonoses, represent a significant threat to global health. Emergence is often driven by anthropogenic activity (e.g. travel, land use change).
Brierley, L, Daszak, P, Jones, KE, Olival, KJ, Vonhof, M   +4 more
core   +1 more source

Influence of Host and Landscape‐Associated Factors in the Infection and Transmission of Pathogens: The Case of Directly Transmitted Virus in Mammals

Veterinary Medicine and Science, Volume 11, Issue 1, January 2025.
The figure shows the effects (increasing upward arrow or decreasing downward arrow) the most common host traits, landscape attributes, climatic features and anthropogenic variables recorded in the review had on the infection and transmission of directly transmitted virus to mammals.
María del Carmen Villalobos‐Segura, Oscar Rico‐Chávez, Gerardo Suzán, Andrea Chaves   +3 more
wiley   +1 more source