Results 71 to 80 of about 3,826 (162)

RAD6A-RAD18 Ubiquitination Complex-mediated Nuclear-cytoplasmic Trafficking and Viral Budding of Henipavirus M Protein

Shengwu huaxue yu shengwu wuli jinzhan
The ubiquitination modification of henipavirus (HNV) M protein is essential for its nuclear-cytoplasmic trafficking and viral budding, but the precise regulatory mechanism has remained unclear.
DUAN Zhi-Qiang
doaj   +1 more source

In Silico Design and Characterization of a Multiepitope Vaccine Candidate Against Brucella canis Using a Reverse Vaccinology Approach

Journal of Immunology Research, Volume 2025, Issue 1, 2025.
Brucella canis is a Gram‐negative bacterium that causes canine brucellosis, a zoonotic disease with serious implications for public health and the global economy. Currently, there is no effective preventive vaccine for B. canis. Control measures include diagnostic testing, isolation, and euthanasia of infected animals.
Vicente Arriagada, Alberto Osorio, Crisleri Carrera-Naipil, Carlos A. Villacis-Aguirre, Cristian Escobar, Nicolás Morales, Danthe Villa, Lien Mardones, Dafne Pérez, Macarena Jara, Raúl E. Molina, Ítalo Ferrari, Sebastián Azocar, Leonardo A. Gómez, Ángel A. Oñate, Baohui Xu   +15 more
wiley   +1 more source

A Functional Genomics Approach to Henipavirus Research: The Role of Nuclear Proteins, MicroRNAs and Immune Regulators in Infection and Disease [PDF]

, 2017
Hendra and Nipah viruses (family Paramyxoviridae, genus Henipavirus) are zoonotic RNA viruses that cause lethal disease in humans and are designated as Biosafety Level 4 (BSL4) agents. Moreover, henipaviruses belong to the same group of viruses that cause disease more commonly in humans such as measles, mumps and respiratory syncytial virus. Due to the
Stewart, CR, Deffrasnes, C, Foo, CH, Bean, AGD, Wang, L-F   +4 more
openaire   +3 more sources

Multi-platform omics analysis of Nipah virus infection reveals viral glycoprotein modulation of mitochondria

Cell Reports
Summary: The recent global pandemic illustrates the importance of understanding the host cellular infection processes of emerging zoonotic viruses. Nipah virus (NiV) is a deadly zoonotic biosafety level 4 encephalitic and respiratory paramyxovirus.
Gunner P. Johnston, Fikret Aydemir, Haewon Byun, Emmie de Wit, Kristie L. Oxford, Jennifer E. Kyle, Jason E. McDermott, Brooke L. Deatherage Kaiser, Cameron P. Casey, Karl K. Weitz, Heather M. Olson, Kelly G. Stratton, Natalie C. Heller, Viraj Upadhye, I. Abrrey Monreal, J. Lizbeth Reyes Zamora, Lei Wu, D.H. Goodall, David W. Buchholz, Joeva J. Barrow, Katrina M. Waters, Ruth N. Collins, Heinz Feldmann, Joshua N. Adkins, Hector C. Aguilar   +24 more
doaj   +1 more source

Validation of Chemical Inactivation Protocols for Henipavirus-Infected Tissue Samples

Viruses
Biocontainment laboratories often have limited access to a range of instruments required for conducting standard assays on infected materials. Consequently, some of the protocols involving infected samples are conducted outside a biocontainment facility.
Daniela Silva-Ayala, Anthony Griffiths
openaire   +2 more sources

Bat‐Borne RNA Viruses: Addressing the Rising Health Risks in Bangladesh

Public Health Challenges, Volume 4, Issue 2, June 2025.
Md Nasir Ahmed
wiley   +1 more source

Interferon Production and Signaling Pathways Are Antagonized during Henipavirus Infection of Fruit Bat Cell Lines

PLoS ONE, 2011
(Uploaded by Plazi for the Bat Literature Project) Bats are natural reservoirs for a spectrum of infectious zoonotic diseases including the recently emerged henipaviruses (Hendra and Nipah viruses). Henipaviruses have been observed both naturally and experimentally to cause serious and often fatal disease in many different mammal species, including ...
Virtue, Elena R., Marsh, Glenn A., Baker, Michelle L., Wang, Lin-Fa, Tripp, Ralph   +4 more
openaire   +6 more sources

Characterization of an mRNA-Encoded Antibody Against Henipavirus

Current Issues in Molecular Biology
Nipah and Hendra viruses are lethal zoonotic pathogens with no approved vaccines or therapeutics. mRNA produced via in vitro transcription enables endogenous protein expression and cost reduction.
Zixuan Liu, Bingjie Sun, Ting Fang, Xiaofan Zhao, Yi Ren, Zhenwei Song, Sijun He, Jianmin Li, Pengfei Fan, Changming Yu   +9 more
doaj   +1 more source

A highly effective ferritin-based divalent nanoparticle vaccine shields Syrian hamsters against lethal Nipah virus

Frontiers in Immunology
The Nipah virus (NiV), a highly deadly bat-borne paramyxovirus, poses a substantial threat due to recurrent outbreaks in specific regions, causing severe respiratory and neurological diseases with high morbidity. Two distinct strains, NiV-Malaysia (NiV-M)
Chunhong Yin, Chunhong Yin, Yan Feng Yao, Yan Feng Yao, Peipei Yang, Peipei Yang, Hang Liu, Hang Liu, Ge Gao, Ge Gao, Yun Peng, Yun Peng, Miaoyu Chen, Miaoyu Chen, Mingqing Lu, Mingqing Lu, Xuekai Zhang, Xuekai Zhang, Weiwei Guo, Weiwei Guo, Zihan Zhang, Zihan Zhang, Xue Hu, Xue Hu, Zhiming Yuan, Zhiming Yuan, Chao Shan, Chao Shan, Chao Shan, Chao Shan   +29 more
doaj   +1 more source

Unravelling the mystery of Nipah virus: from virus to therapeutics: current insights and future frontiers

Bulletin of the National Research Centre
Background Nipah virus (NiV) is a high-risk zoonotic infection that results in severe respiratory and neurological disease, with case fatality rates typically exceeding 70%. Driven by reservoir-host spillover and intermittent human-to-human transmission,
Jignesh Bhate, Rakesh Jain, Arun Vivek Jayabalan   +2 more
doaj   +1 more source