Results 51 to 60 of about 4,648 (202)

Crystal Structure of the Pre-fusion Nipah Virus Fusion Glycoprotein Reveals a Novel Hexamer-of-Trimers Assembly. [PDF]

, 2015
Nipah virus (NiV) is a paramyxovirus that infects host cells through the coordinated efforts of two envelope glycoproteins. The G glycoprotein attaches to cell receptors, triggering the fusion (F) glycoprotein to execute membrane fusion.
Aguilar, Hector C, Akyol-Ataman, Zeynep, Bradel-Tretheway, Birgit, Broder, Christopher C, Chan, Yee-Peng, Dutta, Somnath, Feng, YanRu, Lee, Benhur, Nikolov, Dimitar B, Skiniotis, Georgios, Wang, Lin-Fa, Xu, Kai, Yan, Lianying, Zhou, Z Hong, Zhu, Yongqun   +14 more
core   +2 more sources

HenipavirusInfection in Fruit Bats (Pteropus giganteus), India

Emerging Infectious Diseases, 2008
(Uploaded by Plazi for the Bat Literature Project) We tested 41 bats for antibodies against Nipah and Hendra viruses to determine whether henipaviruses circulate in pteropid fruit bats (Pteropus giganteus) in northern India. Twenty bats were seropositive for Nipah virus, which suggests circulation in this species, thereby extending the known ...
Epstein, Jonathan H., Prakash, Vibhu, Smith, Craig S., Daszak, Peter, McLaughlin, Amanda B., Meehan, Greer, Field, Hume E., Cunningham, Andrew A.   +7 more
openaire   +4 more sources

Protection Against Henipavirus Infection by Use of Recombinant Adeno-Associated Virus–Vector Vaccines [PDF]

The Journal of Infectious Diseases, 2012
Nipah virus (NiV) and Hendra virus (HeV) are closely related, recently emerged paramyxoviruses that are capable of causing considerable morbidity and mortality in several mammalian species, including humans. Henipavirus-specific vaccines are still commercially unavailable, and development of novel antiviral strategies to prevent lethal infections due ...
Ploquin, Aurélie, Szécsi, Judit, Mathieu, Cyrille, Guillaume, Vanessa, Barateau, Véronique, Ong, Kien Chai, Wong, Kum Thong, François-Loïc, Cosset, Horvat, Branka, Salvetti, Anna   +9 more
openaire   +3 more sources

Henipavirus Immune Evasion and Pathogenesis Mechanisms: Lessons Learnt from Natural Infection and Animal Models

Viruses, 2022
Nipah henipavirus (NiV) and Hendra henipavirus (HeV) are zoonotic emerging paramyxoviruses causing severe disease outbreaks in humans and livestock, mostly in Australia, India, Malaysia, Singapore and Bangladesh. Both are bat-borne viruses and in humans, their mortality rates can reach 60% in the case of HeV and 92% for NiV, thus being two of the ...
Philip Lawrence, Beatriz Escudero-Pérez
openaire   +3 more sources

Global trends in infectious diseases at the wildlife–livestock interface [PDF]

, 2015
The role and significance of wildlife–livestock interfaces in disease ecology has largely been neglected, despite recent interest in animals as origins of emerging diseases in humans. Scoping review methods were applied to objectively assess the relative
Anke K. Wiethoelter, Bengis, Bengis, Chardonnet, Daniel Beltrán-Alcrudo, Dehove, Kock, Muggeo, Richard Kock, Siobhan M. Mor, Song, Williams   +11 more
core   +2 more sources

Clinical Outcome of Henipavirus Infection in Hamsters Is Determined by the Route and Dose of Infection [PDF]

Journal of Virology, 2011
ABSTRACTNipah virus (NiV) and Hendra virus (HeV) are emerging zoonotic viruses and the causative agents of severe respiratory disease and encephalitis in humans. Little is known about the mechanisms that govern the development of respiratory and neurological disease.
Barry, Rockx, Douglas, Brining, Joshua, Kramer, Julie, Callison, Hideki, Ebihara, Keith, Mansfield, Heinz, Feldmann   +6 more
openaire   +2 more sources

Henipavirus Infections - An Expanding Zoonosis from Fruit Bats

Journal of Disaster Research, 2011
The henipavirus genus has two members – the Hendra virus (HeV) and the Nipah virus (NiV). HeV and NiV, identified in the 1990s as a paramyxovirus, cause fatalities in humans and animals. They are now classified as biosafety level 4 pathogens. HeV caused fatal respiratory infection in horses and humans in Australia in 1994, in which 2 persons died.
Chieko Kai, Misako Yoneda
openaire   +1 more source

Protease inhibitors targeting coronavirus and filovirus entry. [PDF]

, 2015
In order to gain entry into cells, diverse viruses, including Ebola virus, SARS-coronavirus and the emerging MERS-coronavirus, depend on activation of their envelope glycoproteins by host cell proteases.
Agudelo, Juliet, Barnard, Dale, Carrion, Ricardo, Lu, Kai, McKerrow, James H, Nunneley, Jerritt W, Pöhlmann, Stefan, Renslo, Adam R, Simmons, Graham, Vedantham, Punitha, Zhou, Yanchen   +10 more
core   +1 more source

Nipah shell disorder, modes of infection, and virulence [PDF]

, 2020
The Nipah Virus (NiV) was first isolated during a 1998–9 outbreak in Malaysia. The outbreak initially infected farm pigs and then moved to humans from pigs with a case-fatality rate (CFR) of about 40%.
Dunker, A. Keith, Foster, James A., Goh, Gerard Kian-Meng, Uversky, Vladimir N.   +3 more
core   +1 more source

Nipah Virus Disease: Epidemiological, Clinical, Diagnostic and Legislative Aspects of This Unpredictable Emerging Zoonosis

Animals, 2022
Nipah virus (NiV) infection is a viral disease caused by a Henipavirus, belonging to the Paramyxoviridae family, responsible for a zoonosis. The course of the disease can be very serious and lead to death.
Luigi Bruno, Maria Anna Nappo, Luca Ferrari, Rosanna Di Lecce, Chiara Guarnieri, Anna Maria Cantoni, Attilio Corradi   +6 more
doaj   +1 more source