Results 51 to 60 of about 3,826 (162)
Recent developments in experimental animal models ofHenipavirusinfection [PDF]
Hendra (HeV) and Nipah (NiV) viruses (genus Henipavirus (HNV; family Paramyxoviridae) are emerging zoonotic agents that can cause severe respiratory distress and acute encephalitis in humans. Given the lack of effective therapeutics and vaccines for human use, these viruses are considered as public health concerns. Several experimental animal models of
openaire +2 more sources
This study explores socioeconomic and health‐related aspects of a bat‐hunter community in Bangladesh, focusing on their unique cultural practices and the associated risks of bat‐borne infections. The hunter community predominantly engages in day labor and seasonal bat hunting as supplementary income.
A. K. M. Dawlat Khan, Hannah Wesley
wiley +1 more source
The Nipah virus (NiV) and the Hendra virus (HeV) are highly pathogenic zoonotic diseases that can cause fatal infections in humans and animals. Early detection is critical for the control of NiV and HeV infections.
Wenjun Zhu +4 more
doaj +1 more source
The Matrix Protein of Nipah Virus Targets the E3-Ubiquitin Ligase TRIM6 to Inhibit the IKKε Kinase-Mediated Type-I IFN Antiviral Response. [PDF]
For efficient replication, viruses have developed mechanisms to evade innate immune responses, including the antiviral type-I interferon (IFN-I) system.
Preeti Bharaj +9 more
doaj +1 more source
Analysis of 57 536 high‐throughput sequencing datasets uncovers a vast, hidden world of viruses in wildlife. The researchers reveal significant geographic and host‐specific patterns of viruses, and their surprising cross‐species transmissions, such as avian flu viruses infecting goats.
Hai Wang +19 more
wiley +1 more source
Henipavirus neutralising antibodies in an isolated island population of African fruit bats. [PDF]
Isolated islands provide valuable opportunities to study the persistence of viruses in wildlife populations, including population size thresholds such as the critical community size.
Alison J Peel +11 more
doaj +1 more source
Integrating host condition into spatiotemporal multiscale models improves virus shedding predictions
Understanding where and when pathogens occur in the environment has implications for reservoir population health and infection risk. In reservoir hosts, infection status and pathogen shedding are affected by processes interacting across different scales: from landscape features affecting host location and transmission to within‐host processes affecting
Andrew M. Kramer +9 more
wiley +1 more source
Mapping the Potential Risk of Coronavirus Spillovers in a Global Hotspot
Bats host a vast array of viruses, including those behind SARS and COVID‐19. This study maps coronavirus spillover risk hotspots across South and Southeast Asia by combining horseshoe bat species distributions, forest fragmentation, and human population density.
R. Sedricke Lapuz +2 more
wiley +1 more source
Potent Cross‐neutralizing Antibodies Reveal Vulnerabilities of Henipavirus Fusion Glycoprotein
Hendra and Nipah viruses (HNVs) pose significant threats to global health. This work reports potent cross‐neutralizing antibodies targeting the fusion glycoprotein (F) and reveals shared features of these antibodies and vulnerabilities of F, thereby guiding the rational design of countermeasures against HNVs and similar pathogens.
Yi Ren +19 more
wiley +1 more source
The emergence of the novel henipavirus, Langya virus, received global attention after the virus sickened over three dozen people in China. There is heightened concern that henipaviruses, as respiratory pathogens, could spark another pandemic, most ...
Courtney Woolsey +12 more
doaj +1 more source

