Results 41 to 50 of about 3,863 (179)

Anti-viral drug discovery against monkeypox and smallpox infection by natural curcumin derivatives: A Computational drug design approach

Frontiers in Cellular and Infection Microbiology, 2023
BackgroundIn the last couple of years, viral infections have been leading the globe, considered one of the most widespread and extremely damaging health problems and one of the leading causes of mortality in the modern period.
Shopnil Akash, Arafat Hossain, Md. Sarowar Hossain, Md. Mominur Rahman, Mohammad Z. Ahmed, Nemat Ali, Martin Valis, Kamil Kuca, Kamil Kuca, Rohit Sharma   +9 more
doaj   +1 more source

Cedar virus biology and its applications as a surrogate for highly pathogenic henipaviruses

Cell Insight
Nipah Virus (NiV) and Hendra Virus (HeV), are the prototype species of the genus Henipavirus and are highly pathogenic agents capable of causing fatal diseases in both animals and humans.
Ahmad Jawad Sabir, Lijun Rong, Christopher C. Broder, Moushimi Amaya   +3 more
doaj   +1 more source

Validation of Chemical Inactivation Protocols for <i>Henipavirus</i>-Infected Tissue Samples. [PDF]

Viruses
Biocontainment laboratories often have limited access to a range of instruments required for conducting standard assays on infected materials. Consequently, some of the protocols involving infected samples are conducted outside a biocontainment facility.
Silva-Ayala D, Griffiths A.
europepmc   +3 more sources

Unveiling emerging threats: Langya and Mojiang—A dance with unfamiliar foes

Infectious Diseases & Immunity
. Langya henipavirus (LayV) and Mojiang henipavirus (MojV) are emerging zoonotic pathogens that were first identified in China in 2018 and 2012 respectively, and are classified within the Henipavirus genus.
Snehasis Nayak, Haijuan Wang
doaj   +1 more source

Type I Interferon Signaling Protects Mice From Lethal Henipavirus Infection [PDF]

The Journal of Infectious Diseases, 2012
Hendra virus (HeV) and Nipah virus (NiV) are closely related, recently emerged paramyxoviruses that form Henipavirus genus and are capable of causing considerable morbidity and mortality in a number of mammalian species, including humans. However, in contrast to many other species and despite expression of functional virus entry receptors, mice are ...
Dhondt, Kévin P, Mathieu, Cyrille, Chalons, Marie, Reynaud, Joséphine M, Vallve, Audrey, Raoul, Hervé, Horvat, Branka   +6 more
openaire   +4 more sources

Henipavirus Immune Evasion and Pathogenesis Mechanisms: Lessons Learnt from Natural Infection and Animal Models

Viruses, 2022
Nipah henipavirus (NiV) and Hendra henipavirus (HeV) are zoonotic emerging paramyxoviruses causing severe disease outbreaks in humans and livestock, mostly in Australia, India, Malaysia, Singapore and Bangladesh. Both are bat-borne viruses and in humans, their mortality rates can reach 60% in the case of HeV and 92% for NiV, thus being two of the ...
Philip Lawrence, Beatriz Escudero-Pérez
openaire   +3 more sources

Characterising the Transcriptomic Response to Interferon and Infection in European Domestic Ferret Respiratory Tissues Using Long‐Read RNA Sequencing

Immunology, Volume 177, Issue 2, Page 299-316, February 2026.
We utilised long‐read Nanopore sequencing to characterise the transcriptome of ferret cell lines stimulated with IFN‐α as well as nasal turbinates from ferrets infected with influenza A virus. We identified novel genes and isoforms and observed elongation of poly(A) tails in the ribosome and Coronavirus Disease‐19 pathways in response to IFN‐α ...
Rubaiyea Farrukee, Jessie J.‐Y. Chang, Jianshu Zhang, James B. Barnes, Shu Xin Zhang, Sher Maine Tan, Patrick C. Reading, Lachlan J. M. Coin   +7 more
wiley   +1 more source

Interferon Signaling Remains Functional during Henipavirus Infection of Human Cell Lines [PDF]

Journal of Virology, 2011
ABSTRACT Henipaviruses encode several proteins from the P gene, of which V and W have been demonstrated by gene-based transfection studies to antagonize the innate immune response, blocking both type I interferon production and signaling. This study examines the effects of henipavirus infection on the innate immune response in human cell ...
Elena R, Virtue, Glenn A, Marsh, Lin-Fa, Wang   +2 more
openaire   +2 more sources

Nipah Virus Disease: Epidemiological, Clinical, Diagnostic and Legislative Aspects of This Unpredictable Emerging Zoonosis

Animals, 2022
Nipah virus (NiV) infection is a viral disease caused by a Henipavirus, belonging to the Paramyxoviridae family, responsible for a zoonosis. The course of the disease can be very serious and lead to death.
Luigi Bruno, Maria Anna Nappo, Luca Ferrari, Rosanna Di Lecce, Chiara Guarnieri, Anna Maria Cantoni, Attilio Corradi   +6 more
doaj   +1 more source

Development of a Porcine Cell Line Stably Expressing Ephrin‐B2 for Nipah Virus Research and Diagnostic Testing

Microbiology and Immunology, Volume 70, Issue 1, Page 36-46, January 2026.
ABSTRACT Nipah virus (NiV) is a highly pathogenic zoonotic virus transmitted from bats to humans through pigs as a crucial intermediate host. NiV outbreaks pose significant public health and economic threats, especially for pig farmers. Although the World Organization for Animal Health recommends African green monkey‐derived Vero cells for NiV ...
Hui Zhang, Akatsuki Saito
wiley   +1 more source