Chemistry Proceedings, 2022 Throughout history, viral epidemics of varying frequency and intensity have been responsible for inducing panic and causing widespread damage. The Nipah virus has one of the highest rates of fatalities of any infectious disease in the world.
Abu Saim Mohammad Saikat +2 more
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The YPLGVG sequence of the Nipah virus matrix protein is required for budding [PDF]
, 2008 Background Nipah virus (NiV) is a recently emerged paramyxovirus capable of causing fatal disease in a broad range of mammalian hosts, including humans.
Yan Lianying +6 more
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Inhibition of Henipavirus infection by RNA interference
Antiviral Research, 2008 Nipah virus (NiV) and Hendra virus (HeV) are recently emerged zoonotic paramyxoviruses exclusively grouped within a new genus, Henipavirus. These viruses cause fatal disease in a wide range of species, including humans. Both NiV and HeV have continued to re-emerge sporadically in Bangladesh and Australia, respectively.
Mungall, Bruce A. +3 more
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Antiviral activity of gliotoxin, gentian violet and brilliant green against Nipah and Hendra virus in vitro [PDF]
, 2009 Background: Using a recently described monolayer assay amenable to high throughput screening format for the identification of potential Nipah virus and Hendra virus antivirals, we have partially screened a low molecular weight compound library (8,000 ...
Mohamad Aljofan +8 more
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Monomeric ephrinB2 binding induces allosteric changes in Nipah virus G that precede its full activation. [PDF]
, 2017 Nipah virus is an emergent paramyxovirus that causes deadly encephalitis and respiratory infections in humans. Two glycoproteins coordinate the infection of host cells, an attachment protein (G), which binds to cell surface receptors, and a fusion (F ...
Jardetzky, Theodore S +9 more
core +2 more sources
Hendra and Nipah virus infection in cultured human olfactory epithelial cells [PDF]
, 2017 Henipaviruses are emerging zoonotic viruses and causative agents of encephalitis in humans. However, the mechanisms of entry into the central nervous system (CNS) in humans are not known.
Barry Rockx +4 more
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Interferon Signaling Remains Functional during Henipavirus Infection of Human Cell Lines [PDF]
Journal of Virology, 2011 ABSTRACT Henipaviruses encode several proteins from the P gene, of which V and W have been demonstrated by gene-based transfection studies to antagonize the innate immune response, blocking both type I interferon production and signaling. This study examines the effects of henipavirus infection on the innate immune response in human cell ...
Elena R, Virtue +2 more
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Frontiers in Cellular and Infection Microbiology, 2023 BackgroundIn the last couple of years, viral infections have been leading the globe, considered one of the most widespread and extremely damaging health problems and one of the leading causes of mortality in the modern period.
Shopnil Akash +9 more
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The Intrinsically Disordered W Protein Is Multifunctional during Henipavirus Infection, Disrupting Host Signalling Pathways and Nuclear Import [PDF]
Cells, 2020 Nipah and Hendra viruses are highly pathogenic, zoonotic henipaviruses that encode proteins that inhibit the host’s innate immune response. The W protein is one of four products encoded from the P gene and binds a number of host proteins to regulate signalling pathways.
Sofiya Tsimbalyuk +5 more
openaire +3 more sources
Cedar virus biology and its applications as a surrogate for highly pathogenic henipaviruses
Cell InsightNipah Virus (NiV) and Hendra Virus (HeV), are the prototype species of the genus Henipavirus and are highly pathogenic agents capable of causing fatal diseases in both animals and humans.
Ahmad Jawad Sabir +3 more
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