Outbreak of Henipavirus Infection, Philippines, 2014
En 2014, l'infection à henipavirus a causé une maladie grave chez les humains et les chevaux dans le sud des Philippines ; les taux de mortalité chez les humains étaient élevés. Une transmission de cheval à humain et d'humain à humain s'est produite. La source la plus probable d'infection des chevaux était les chauves-souris frugivores.
Paola Katrina Ching +16 more
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Clinical perspectives of emerging pathogens in bleeding disorders. [PDF]
As a result of immunological and nucleic-acid screening of plasma donations for transfusion-transmissible viruses, and the incorporation of viral reduction processes during plasma fractionation, coagulation-factor concentrates (CFC) are now judged safe ...
Bozzette, Samuel +11 more
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Nipah and Hendra viruses are deadly zoonotic paramyxoviruses with a case fatality rate of upto 75%. The viruses belong to the genus henipavirus in the family Paramyxoviridae, a family of negative-sense single-stranded RNA viruses.
Sabahat Gazal +7 more
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Rhabdovirus-based vaccine platforms against henipaviruses. [PDF]
UNLABELLED: The emerging zoonotic pathogens Hendra virus (HeV) and Nipah virus (NiV) are in the genus Henipavirus in the family Paramyxoviridae. HeV and NiV infections can be highly fatal to humans and livestock.
Feldmann, Heinz +4 more
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Zoonosis emergence linked to agricultural intensification and environmental change [PDF]
A systematic review was conducted by a multidisciplinary team to analyze qualitatively best available scientific evidence on the effect of agricultural intensification and environmental changes on the risk of zoonoses for which there are epidemiological ...
Artois +59 more
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Reprogrammed Pteropus Bat Stem Cells as A Model to Study Host-Pathogen Interaction during Henipavirus Infection [PDF]
Bats are natural hosts for numerous zoonotic viruses, including henipaviruses, which are highly pathogenic for humans, livestock, and other mammals but do not induce clinical disease in bats. Pteropus bats are identified as a reservoir of henipaviruses and the source of transmission of the infection to humans over the past 20 years.
Aurine, Noémie +8 more
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Immunopathogenesis of Nipah Virus Infection and Associated Immune Responses
Pandemics in the last two centuries have been initiated by causal pathogens that include Severe Acute Coronavirus 2 (SARS-CoV-2) and Influenza (e.g., the H1N1 pandemic of 2009).
Brent Brown +7 more
doaj +1 more source
Subclinical infection without encephalitis in mice following intranasal exposure to Nipah virus-Malaysia and Nipah virus-Bangladesh [PDF]
BACKGROUND: Nipah virus and Hendra virus are closely related and following natural or experimental exposure induce similar clinical disease. In humans, encephalitis is the most serious outcome of infection and, hitherto, research into the pathogenesis of
Deborah Middleton +5 more
core +1 more source
Animal Challenge Models of Henipavirus Infection and Pathogenesis [PDF]
The henipaviruses, Hendra virus (HeV), and Nipah virus (NiV), are enigmatic emerging pathogens that causes severe and often fatal neurologic and/or respiratory disease in both animals and humans. Amongst people, case fatality rates range between 40 and 75% and there are no vaccines or treatments approved for human use.
Geisbert, Thomas W. +2 more
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Type I Interferon Signaling Protects Mice From Lethal Henipavirus Infection [PDF]
Hendra virus (HeV) and Nipah virus (NiV) are closely related, recently emerged paramyxoviruses that form Henipavirus genus and are capable of causing considerable morbidity and mortality in a number of mammalian species, including humans. However, in contrast to many other species and despite expression of functional virus entry receptors, mice are ...
Dhondt, Kévin P +6 more
openaire +4 more sources

