Results 11 to 20 of about 4,648 (202)

Host gene expression profiles in ferrets infected with genetically distinct henipavirus strains. [PDF]

PLoS Neglected Tropical Diseases, 2018
Henipavirus infection causes severe respiratory and neurological disease in humans that can be fatal. To characterize the pathogenic mechanisms of henipavirus infection in vivo, we performed experimental infections in ferrets followed by genome-wide gene
Alberto J Leon, Viktoriya Borisevich, Nahal Boroumand, Robert Seymour, Rebecca Nusbaum, Olivier Escaffre, Luoling Xu, David J Kelvin, Barry Rockx   +8 more
doaj   +6 more sources

Genome-wide siRNA Screening at Biosafety Level 4 Reveals a Crucial Role for Fibrillarin in Henipavirus Infection.

PLoS Pathogens, 2016
Hendra and Nipah viruses (genus Henipavirus, family Paramyxoviridae) are highly pathogenic bat-borne viruses. The need for high biocontainment when studying henipaviruses has hindered the development of therapeutics and knowledge of the viral infection ...
Celine Deffrasnes, Glenn A Marsh, Chwan Hong Foo, Christina L Rootes, Cathryn M Gould, Julian Grusovin, Paul Monaghan, Michael K Lo, S Mark Tompkins, Timothy E Adams, John W Lowenthal, Kaylene J Simpson, Cameron R Stewart, Andrew G D Bean, Lin-Fa Wang   +14 more
doaj   +6 more sources

Heparan Sulfate-Dependent Enhancement of Henipavirus Infection [PDF]

mBio, 2015
Nipah virus and Hendra virus are emerging, highly pathogenic, zoonotic paramyxoviruses that belong to the genus Henipavirus. They infect humans as well as numerous mammalian species.
Cyrille Mathieu, Kévin P. Dhondt, Marie Châlons, Stéphane Mély, Hervé Raoul, Didier Negre, François-Loïc Cosset, Denis Gerlier, Romain R. Vivès, Branka Horvat   +9 more
doaj   +4 more sources

Henipavirus RNA in African bats. [PDF]

PLoS ONE, 2009
BackgroundHenipaviruses (Hendra and Nipah virus) are highly pathogenic members of the family Paramyxoviridae. Fruit-eating bats of the Pteropus genus have been suggested as their natural reservoir.
Jan Felix Drexler, Victor Max Corman, Florian Gloza-Rausch, Antje Seebens, Augustina Annan, Anne Ipsen, Thomas Kruppa, Marcel A Müller, Elisabeth K V Kalko, Yaw Adu-Sarkodie, Samuel Oppong, Christian Drosten   +11 more
doaj   +3 more sources

Indirect ELISA based on Hendra and Nipah virus proteins for the detection of henipavirus specific antibodies in pigs. [PDF]

PLoS ONE, 2018
Hendra virus (HeV) and Nipah virus (NiV) belong to the genus Henipavirus in the family Paramyxoviridae. Henipavirus infections were first reported in the 1990's causing severe and often fatal outbreaks in domestic animals and humans in Southeast Asia and
Kerstin Fischer, Sandra Diederich, Greg Smith, Sven Reiche, Vinicius Pinho Dos Reis, Eileen Stroh, Martin H Groschup, Hana M Weingartl, Anne Balkema-Buschmann   +8 more
doaj   +3 more sources

Evidence of Henipavirus Infection in West African Fruit Bats

PLoS ONE, 2008
(Uploaded by Plazi for the Bat Literature Project) Henipaviruses are emerging RNA viruses of fruit bat origin that can cause fatal encephalitis in man. Ghanaian fruit bats (megachiroptera) were tested for antibodies to henipaviruses. Using a Luminex multiplexed microsphere assay, antibodies were detected in sera of Eidolon helvum to both Nipah (39%, 95%
David T. S. Hayman, Richard Suu‐Ire, Andrew C. Breed, Jennifer A. McEachern, Lin‐Fa Wang, James Wood, Andrew A. Cunningham   +6 more
openaire   +7 more sources

What is stirring in the reservoir? Modelling mechanisms of henipavirus circulation in fruit bat hosts [PDF]

Philosophical Transactions of the Royal Society B: Biological Sciences, 2019
Pathogen circulation among reservoir hosts is a precondition for zoonotic spillover. Unlike the acute, high morbidity infections typical in spillover hosts, infected reservoir hosts often exhibit low morbidity and mortality. Although it has been proposed
Becker, DJ, Cunningham, AA, Garnier, R, Gibson, L, Glennon, EE, Hayman, DTS, Peel, AJ, Plowright, RK, Restif, O, Suu-Ire, RD, Wood, JLN   +10 more
core   +2 more sources

Bat trait, genetic and pathogen data from large-scale investigations of African fruit bats, Eidolon helvum. [PDF]

, 2016
Bats, including African straw-coloured fruit bats (Eidolon helvum), have been highlighted as reservoirs of many recently emerged zoonotic viruses. This common, widespread and ecologically important species was the focus of longitudinal and continent-wide
Baker, Kate S, Breed, Andrew C, Cunningham, Andrew A, Fernández-Loras, Andrés, Fooks, Anthony R, Gembu, Guy-Crispin, Hayman, David TS, Lembo, Tiziana, Peel, Alison J, Sargan, David R, Suu-Ire, Richard, Wood, James LN   +11 more
core   +14 more sources

Nipah: The Jumping Virus [PDF]

National Journal of Laboratory Medicine, 2020
Nipah virus (NiV), infection is an emerging zoonosis with a high mortality rate, and severe neurological and respiratory involvement in humans. NiV, a Paramyxovirus belonging to the genus Henipavirus is highly pathogenic and has a mortality rate which ...
Anuradha Sharma, Anupriya Wadhwa
doaj   +1 more source

Henipavirus infection of the central nervous system [PDF]

Pathogens and Disease, 2019
ABSTRACTNipah virus (NiV) and Hendra virus are highly pathogenic zoonotic viruses of the genus Henipavirus, family Paramyxoviridae. These viruses were first identified as the causative agents of severe respiratory and encephalitic disease in the 1990s across Australia and Southern Asia with mortality rates reaching up to 75%.
Brian E, Dawes, Alexander N, Freiberg
openaire   +2 more sources