Results 61 to 70 of about 3,826 (162)

Henipavirus Infections - An Expanding Zoonosis from Fruit Bats

Journal of Disaster Research, 2011
The henipavirus genus has two members – the Hendra virus (HeV) and the Nipah virus (NiV). HeV and NiV, identified in the 1990s as a paramyxovirus, cause fatalities in humans and animals. They are now classified as biosafety level 4 pathogens. HeV caused fatal respiratory infection in horses and humans in Australia in 1994, in which 2 persons died.
Chieko Kai, Misako Yoneda
openaire   +1 more source

Land Use Change and Infectious Disease Emergence

Reviews of Geophysics, Volume 63, Issue 2, June 2025.
Abstract Major infectious diseases threatening human health are transmitted to people from animals or by arthropod vectors such as insects. In recent decades, disease outbreaks have become more common, especially in tropical regions, including new and emerging infections that were previously undetected or unknown. Even though there is growing awareness
M. Cristina Rulli, Paolo D’Odorico, Nikolas Galli, Reju S. John, Renata L. Muylaert, Monia Santini, David T. S. Hayman   +6 more
wiley   +1 more source

A conserved motif in Henipavirus P/V/W proteins drives the fibrillation of the W protein from Hendra virus

Protein Science, Volume 34, Issue 4, April 2025.
Abstract The Hendra (HeV) and Nipah (NiV) viruses are high‐priority, biosafety level‐4 pathogens that cause fatal neurological and respiratory disease. Their P gene encodes not only the P protein, an essential polymerase cofactor, but also the virulence factors V and W.
Frank Gondelaud, Christophe Bignon, Denis Ptchelkine, Frédéric Carrière, Sonia Longhi   +4 more
wiley   +1 more source

In silico Drug Discovery of Novel Small Lead Compounds Targeting Nipah Virus Attachment Glycoprotein

Journal of Integrated Health Sciences, 2018
Introduction: Nipah virus (NiV) and Hendra virus are the type species of the highly pathogenic paramyxovirus genus Henipavirus, which can cause severe respiratory disease and fatal encephalitis infections in humans.
Ashish P. Shah, Bhumika M. Parmar, Mubasarin A. Ghodawala, Avinashkumar Seth   +3 more
doaj   +1 more source

Unraveling the molecular grammar and the structural transitions underlying the fibrillation of a viral fibrillogenic domain

Protein Science, Volume 34, Issue 3, March 2025.
Abstract Hendra virus (HeV) is a biosafety level 4 human pathogen belonging to the Henipavirus genus within the Paramyxoviridae family. In HeV, the phosphoprotein‐encoding gene also drives the synthesis of the V and W proteins that are two major players in the host innate immune response evasion.
Frank Gondelaud, Julien Leval, Lisha Arora, Anuja Walimbe, Christophe Bignon, Denis Ptchelkine, Stefania Brocca, Samrat Mukhopadyay, Sonia Longhi   +8 more
wiley   +1 more source

Emerging Nipah Virus With Pandemic Potential and High Mortality Rates: Is the Scientific Community Learning From Former Pandemics?

Reviews in Medical Virology, Volume 35, Issue 2, March 2025.
ABSTRACT As Nipah virus (NiV) infection is characterised by a possible pandemic risk, being currently limited to a small but deadly belt, the attention of other countries is essential. It has often been pointed out that NiV is an under‐researched virus with a high‐risk potential. This study aimed to show the global research history and status quo based
Doris Klingelhöfer, Markus Braun, Christina A. Naser, Dörthe Brüggmann, David A. Groneberg   +4 more
wiley   +1 more source

The Current Pathogenicity and Potential Risk Assessment of Nipah Virus as Potential Cause of “Disease X”: A Narrative Review

Health Science Reports
Background and Aims The World Health Organization (WHO) recognized the potential for a severe international epidemic and introduced the term “Disease X” to classify pathogens that not yet identified.
Samiha Mehnaz, Ramisa Anjum, Fatema Rahman Mithila, Syed Masudur Rahman Dewan, Md. Rabiul Islam   +4 more
doaj   +1 more source

Chiroptera as a Potential Reservoir of Dangerous for Humans Viruses in the territory of the Republic of Guinea. Part 1

Проблемы особо опасных инфекций, 2018
Chiroptera is one of the largest in numbers orders of mammals which can take on the role of natural host and vector of various viruses, bacteria, and pathogenic fungi.
A. M. Porshakov, Yu. V. Kononova, V. B. Loktev, M. I. Boiro   +3 more
doaj   +1 more source

Dissecting Henipavirus W proteins conformational and fibrillation properties: contribution of their N‐ and C‐terminal constituent domains

The FEBS Journal, Volume 292, Issue 3, Page 556-581, February 2025.
The W proteins of Nipah and Hendra viruses exhibit fibrillation abilities in vitro, which have been attributed to the intrinsically disordered N‐terminal domain (NTD). Our research shows that the C‐terminal domain (CTD) of both viruses is intrinsically disordered and non‐fibrillogenic.
Giulia Pesce, Frank Gondelaud, Denis Ptchelkine, Christophe Bignon, Patrick Fourquet, Sonia Longhi   +5 more
wiley   +1 more source

Influence of Host and Landscape‐Associated Factors in the Infection and Transmission of Pathogens: The Case of Directly Transmitted Virus in Mammals

Veterinary Medicine and Science, Volume 11, Issue 1, January 2025.
The figure shows the effects (increasing upward arrow or decreasing downward arrow) the most common host traits, landscape attributes, climatic features and anthropogenic variables recorded in the review had on the infection and transmission of directly transmitted virus to mammals.
María del Carmen Villalobos‐Segura, Oscar Rico‐Chávez, Gerardo Suzán, Andrea Chaves   +3 more
wiley   +1 more source