Results 101 to 110 of about 29,438 (248)

Bright spots in the darkness of cancer: A review of starfishes-derived compounds and their anti-tumor action [PDF]

, 2019
The fight against cancer represents a great challenge for researchers and, for this reason, the search for new promising drugs to improve cancer treatments has become inevitable.
Arizza V., Lazzara V., Luparello C., Mauro M., Vazzana M.   +4 more
core   +1 more source

Characterization of the carboxypeptidase N secreted by Hep G2 cells.

Journal of Biological Chemistry, 1988
Human hepatoma (Hep G2) cells secrete nanogram quantities of carboxypeptidase enzymes which are capable of hydrolyzing COOH-terminal lysine and arginine residues. A carboxypeptidase with a neutral pH optimum (greater than pH 7.0) was partially purified from the conditioned medium and compared with pure plasma carboxypeptidase N. The two enzymes behaved
B G, Grimwood, T H, Plummer, A L, Tarentino   +2 more
openaire   +2 more sources

Disruption of ATP Synthase Spatiotemporal Organization, Ca2+ Dynamics, and Contractile Function in Senescent Cardiomyocytes

Aging Cell, Volume 25, Issue 2, February 2026.
Enhanced ATP hydrolysis, ΔΨm flickering, and destabilized ATP synthase dimers collectively reduce ATP availability in senescent cardiomyocytes. This energy deficit is associated with disrupted Ca2⁺ dynamics and contractility. ABSTRACT Heart disease is the leading cause of death in the elderly population.
Silke Morris, Nico Marx, Gonzalo Barrientos, Isidora Molina‐Riquelme, Frank Schmelter, Hugo E. Verdejo, Stefan Peischard, Guiscard Seebohm, Verónica Eisner, Karin B. Busch   +9 more
wiley   +1 more source

Inula viscosa L. Ekstraktı ile Yeşil Sentez Yöntemiyle Elde Edilen Selenyum Nanopartiküllerinin (An-Senp) Hep-G2 Karaciğer Kanseri Hücreleri Üzerindeki Sitotoksik Etkisinin Değerlendirilmesi

Turkish Journal of Agriculture: Food Science and Technology
Bu çalışmada, yeşil sentez yöntemiyle elde edilen selenyum nanopartiküllerinin (An-SeNP) insan karaciğer kanseri hücre hattı (Hep-G2) üzerindeki sitotoksik etkileri araştırılmıştır. Sentez işlemi sırasında Inula viscosa L.
Zekerya Bıçak, Aysel Kekillioğlu, Feride Nur Öztürk   +2 more
doaj   +1 more source

Possible role of GADD45γ methylation in diffuse large B-cell Lymphoma: Does it affect the progression and tissue involvement? [PDF]

, 2015
Objective: Diffuse large B-cell lymphoma (DLBCL) is the most common type of non-Hodgkin lymphoma among adults and is characterized by heterogeneous clinical, immunophenotypic, and genetic features.
Barış, İkbal Cansu, Bağcı, Gülseren, Can, Özge, Caner, Vildan, Doğu, Mehmet Hilmi, Hacıoğlu, Sibel, Keskin, Ali, Sarı, İsmail, Tepeli, Emre, Türk, Nilay Şen, Çetin, Ozan   +10 more
core   +2 more sources

Remote light-controlled intracellular target recognition by photochromic fluorescent glycoprobes [PDF]

, 2017
Development of powerful fluorescence imaging probes and techniques sets the basis for the spatiotemporal tracking of cells at different physiological and pathological stages.
Feringa, Ben L., Fu, Youxin, Han, Hai-Hao, He, Xiao-Peng, Li, Jia, Tian, He, Zang, Yi, Zhang, Junji   +7 more
core   +2 more sources

Unravelling the mechanisms that determine the uptake and metabolism of magnetic single and multicore nanoparticles in a Xenopus laevis model. [PDF]

, 2018
Multicore superparamagnetic nanoparticles have been proposed as ideal tools for some biomedical applications because of their high magnetic moment per particle, high specific surface area and long term colloidal stability.
A. Ruiz, Alexiou, Balakumaran, Balas, C. J. Morris, Crichton, Crichton, Dutz, E. Lozano-Velasco, Eisenstein, Elgrabli, G. N. Wheeler, Geppert, Giannaccini, Glahn, Goldstein, Gu, Gutierrez, Gutierrez, H. Gavilán, Hanini, Hohnholt, I. Rodríguez-Ramiro, James-Zorn, Jia, Jordan, Jun, Kolosnjaj-Tabi, L. Gutiérrez, LaConte, Laurent, Lázaro, Lázaro, M. Marín-Barba, M. P. Morales, Mahmoudi, Mamusa, Martin, Martina, Mazuel, Mazuel, Mejias, Mejías, Mulens-Arias, Mulvaney, Nations, Nations, Osborne, Roger, Rojas, Rojas, Ruiz, Ruiz, Salas, Schutt, Silva, Sun, Tomlinson, Torchilin, Waldvogel-Abramowski, Webster, Weissleder, Xie, Yildiz   +63 more
core   +3 more sources

Requirement of Activation for Hepatitis B Virus Infection [PDF]

, 2007
Although _in vitro_ models of human hepatitis B virus replication are established, so far none could approximate infection efficiency as expected from _in vivo_ observations.
Claudia Maenz, Michael Bruns
core   +1 more source

Tauroursodeoxycholic acid exerts anticholestatic effects by a cooperative cPKC alpha-/PKA-dependent mechanism in rat liver. [PDF]

, 2008
Objective: Ursodeoxycholic acid (UDCA) exerts anticholestatic effects in part by protein kinase C (PKC)-dependent mechanisms. Its taurine conjugate, TUDCA, is a cPKCa agonist.
Beuers, U., Denk, G.U., Hohenester, S., Pusl, T., Rust, C., Wimmer, R.   +5 more
core   +1 more source

Apolipoprotein B synthesized by Hep G2 cells undergoes fatty acid acylation.

Journal of Lipid Research, 1988
Apolipoprotein B is the principal protein associated with cholesterol transport in the blood and has been proposed to play a central role in human atherogenesis.
J M Hoeg, M S Meng, R Ronan, S J Demosky, Jr, T Fairwell, H B Brewer, Jr   +5 more
doaj   +1 more source