Cathepsin Inhibitor Suppresses the Growth of Ectopic Hepatocellular Carcinoma Tumors in Mouse Models. [PDF]
Crown O +4 more
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Macrocyclic histone deacetylase inhibitor-based near-infrared-responsive ionic nanomedicines for enhanced cancer therapy. [PDF]
Oyebade A +8 more
europepmc +1 more source
ANGPTL8 regulates glucose metabolism in gestational diabetes mellitus mice, and proteomic analysis reveals the PI3K/Akt pathway plays its role in insulin-resistance HepG<sub>2</sub> cells. [PDF]
Xie X, Yan J, Chen X, He L, Wu J, Lu L.
europepmc +1 more source
AI-Driven Design and Comparative Evaluation of SNEDDS for the Optimized Nanoencapsulation of Phytoextracts. [PDF]
Prieto-Medrano CG +7 more
europepmc +1 more source
Sustainable development of novel zinc oxide nano flowers mediated red yeast rice for control of hepatocellular carcinoma. [PDF]
Jasim AJ +8 more
europepmc +1 more source
Purpose: Human carcinoma cells with different p53 status exposed to a combination of bioactive substances, resveratrol and berberine, revealed different responses in cell viability via p53-dependant apoptosis pathway activation.
Magdalena Skonieczna +2 more
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Endogenous forms of fibrinogen in hep g2 cells
Thrombosis Research, 1987The three polypeptide chains of fibrinogen, A alpha, B beta and gamma chain, are synthesized on separate polysomes. Fully formed fibrinogen is a six chain, disulfide-linked, dimeric molecule with a molecular weight of 340kDa. Previous pulse-chase studies with L-35 S methionine using the human hepatocellular carcinoma cell line, Hep-G2, showed that the ...
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Lipid and lipoprotein metabolism in Hep G2 cells
Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism, 1988Lipid composition, lipid synthesis and lipoprotein secretion by the Hep G2 cell line have been studied with substrate and insulin supplied under different conditions. The lipid composition of Hep G2 cells was close to that of normal human liver, except for a higher content in sphingomyelin (P less than 0.005) and a lower phosphatidylcholine ...
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Drug metabolism by the human hepatoma cell, Hep G2
Biochemical and Biophysical Research Communications, 1987The human liver-derived cell line, Hep G2, has aryl hydrocarbon hydroxylase and 7-ethoxycoumarin o-de-ethylase activities. Partial purification of cytochrome P-450 from Hep G2 cells provided spectral evidence of this hemeprotein in the purified fraction.
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