Viruses, 2022 Hepaciviruses represent a group of viruses that pose a significant threat to the health of humans and animals. During the last decade, new members of the genus Hepacivirus have been identified in various host species worldwide, indicating the widespread ...
Xue-Lian Zhang +6 more
doaj +2 more sources
Viruses in Horses with Neurologic and Respiratory Diseases [PDF]
Viruses, 2019 Metagenomics was used to identify viral sequences in the plasma and CSF (cerobrospinal fluid) of 13 horses with unexplained neurological signs and in the plasma and respiratory swabs of 14 horses with unexplained respiratory signs. Equine hepacivirus and
Eda Altan +7 more
doaj +3 more sources
Canine Hepacivirus NS3 Serine Protease Can Cleave the Human Adaptor Proteins MAVS and TRIF [PDF]
, 2012 Canine hepacivirus (CHV) was recently identified in domestic dogs and horses. The finding that CHV is genetically the virus most closely related to hepatitis C virus (HCV) has raised the question of whether HCV might have evolved as the result of close ...
Clotet Sala, Bonaventura +5 more
core +3 more sources
Phenotype and Fate of Liver-Resident CD8 T Cells During Acute and Chronic Hepacivirus Infection [PDF]
PLoS Pathogens, 2023 Immune correlates of hepatitis C virus (HCV) clearance and control remain poorly defined due to the lack of an informative animal model. We recently described acute and chronic rodent HCV-like virus (RHV) infections in lab mice.
Attia, Zayed +14 more
core +3 more sources
Neutralization and receptor use of infectious culture–derived rat hepacivirus as a model for HCV
Hepatology, Volume 76, Issue 5, Page 1506-1519, November 2022., 2022 Lack of tractable immunocompetent animal models amenable to robust experimental challenge impedes vaccine efforts for HCV. Infection with rodent hepacivirus from Rattus norvegicus (RHV‐rn1) in rats shares HCV‐defining characteristics, including liver ...
Raphael Wolfisberg +12 more
semanticscholar +2 more sources
Hepatitis viruses: prevalence of equine parvovirus‐hepatitis virus and equine hepacivirus in France and Australia [PDF]
Equine Veterinary Journal, 2021 Background: Recent identification of viruses considered responsible for Theiler’s disease (acute hepatitis) in horses include equine parvovirus-hepatitis (EqPV-H) and the most likely of several flaviviruses, equine hepacivirus (EqHV).
Christine Fortier +11 more
openalex +2 more sources
Dose-Dependent Hepacivirus Infection Reveals Linkage between Infectious Dose and Immune Response
Microbiology Spectrum, 2022 More than 70 million people worldwide are still infected with the hepatitis C virus 30 years after its discovery, underscoring the need for a vaccine. To develop an effective prophylactic vaccine, detailed knowledge of the correlates of protection and an
André Gömer +9 more
doaj +2 more sources
Influence of Host and Landscape-Associated Factors in the Infection and Transmission of Pathogens: The Case of Directly Transmitted Virus in Mammals. [PDF]
Vet Med SciThe figure shows the effects (increasing upward arrow or decreasing downward arrow) the most common host traits, landscape attributes, climatic features and anthropogenic variables recorded in the review had on the infection and transmission of directly transmitted virus to mammals.
Villalobos-Segura MDC +3 more
europepmc +2 more sources
European College of Equine Internal Medicine consensus statement on equine flaviviridae infections in Europe [PDF]
Journal of Veterinary Internal Medicine, 2022 Horses and other equids can be infected with several viruses of the family Flaviviridae, belonging to the genus Flavivirus and Hepacivirus. This consensus statement focuses on viruses with known occurrence in Europe, with the objective to summarize the ...
Jessika‐M. V. Cavalleri +6 more
doaj +3 more sources
Expanded Diversity and Host Range of Bovine Hepacivirus—Genomic and Serological Evidence in Domestic and Wild Ruminant Species [PDF]
Viruses, 2022 The hepatitis C virus (HCV)-related bovine hepacivirus (BovHepV) can cause acute as well as persistent infections in cattle. The true clinical relevance of the virus is not yet known.
Jana Breitfeld +8 more
openalex +2 more sources