Two bovine hepacivirus genome sequences from U.S. cattle. [PDF]
J Vet Diagn InvestBovine hepacivirus (BoHV) is closely related to the hepatitis C virus (HCV) in humans and can cause both acute and chronic liver infections in cattle.
Workman AM +3 more
europepmc +4 more sources
Immune protection against reinfection with nonprimate hepacivirus [PDF]
Proceedings of the National Academy of Sciences, 2017 Significance Hepatitis C virus (HCV) displays a narrow species tropism severely hampering development of small animal models that are required for vaccine and pathogenesis studies in vivo. The recent discoveries of HCV-related hepaciviruses in diverse hosts offer new opportunities with respect to the development of an immunocompetent animal ...
Stephanie Pfaender +22 more
openalex +5 more sources
Mouse models of acute and chronic hepacivirus infection [PDF]
Science, 2017 New York City rats provide a gift to virologists Despite the development of curative drugs for hepatitis C virus (HCV) infection, global eradication of HCV will likely require a prophylactic vaccine. Progress toward a vaccine has been impeded by the absence of mouse models suitable for studying the immune response to HCV ...
Eva Billerbeck +14 more
openalex +5 more sources
Dose-Dependent Hepacivirus Infection Reveals Linkage between Infectious Dose and Immune Response
Microbiology Spectrum, 2022 More than 70 million people worldwide are still infected with the hepatitis C virus 30 years after its discovery, underscoring the need for a vaccine. To develop an effective prophylactic vaccine, detailed knowledge of the correlates of protection and an
André Gömer +9 more
doaj +2 more sources
Nonprimate Hepaciviruses in Domestic Horses, United Kingdom [PDF]
Emerging Infectious Diseases, 2012 Although the origin of hepatitis C virus infections in humans remains undetermined, a close homolog of this virus, termed canine hepacivirus (CHV) and found in respiratory secretions of dogs, provides evidence for a wider distribution of hepaciviruses in
Sinéad Lyons +8 more
doaj +3 more sources
Hallmarks of Hepatitis C Virus in Equine Hepacivirus [PDF]
Journal of Virology, 2014 ABSTRACT Equine hepacivirus (EHcV) has been identified as a closely related homologue of hepatitis C virus (HCV) in the United States, the United Kingdom, and Germany, but not in Asian countries. In this study, we genetically and serologically screened 31 serum samples obtained from Japanese-born domestic horses for EHcV ...
Tomohisa Tanaka +13 more
openalex +3 more sources
Mutational Analysis of the Bovine Hepacivirus Internal Ribosome Entry Site [PDF]
Journal of Virology, 2018 Several members of the family Flaviviridae , including HCV, have adapted cap-independent translation strategies to overcome canonical eukaryotic translation pathways and use cis -acting RNA-elements, designated viral internal ribosome entry sites (IRES), to initiate translation.
Anna Lena Baron +3 more
openalex +4 more sources
Hepatitis viruses: prevalence of equine parvovirus‐hepatitis virus and equine hepacivirus in France and Australia [PDF]
Equine Veterinary Journal, 2021 Background: Recent identification of viruses considered responsible for Theiler’s disease (acute hepatitis) in horses include equine parvovirus-hepatitis (EqPV-H) and the most likely of several flaviviruses, equine hepacivirus (EqHV).
C. Fortier +11 more
semanticscholar +2 more sources
Postexposure prophylaxis against hepatitis B, hepatitis C and human immunodeficiency virus infection in healthcare workers [PDF]
Vojnosanitetski Pregled, 2011 nema
Vasić Bojan +6 more
doaj +3 more sources
Expanded Diversity and Host Range of Bovine Hepacivirus—Genomic and Serological Evidence in Domestic and Wild Ruminant Species [PDF]
Viruses, 2022 The hepatitis C virus (HCV)-related bovine hepacivirus (BovHepV) can cause acute as well as persistent infections in cattle. The true clinical relevance of the virus is not yet known.
J. Breitfeld +8 more
semanticscholar +2 more sources