Results 21 to 30 of about 44,632 (248)

Detection and characterization of bovine hepacivirus in cattle and sheep from Hulunbuir, northeastern China. [PDF]

Front Cell Infect Microbiol
Background Bovine hepacivirus (BovHepV) is a recently identified member of the expanding genus Hepacivirus within the family Flaviviridae. However, the genetic diversity, geographical distribution, and host range of the virus remains poorly understood ...
Ma J, Wei Z, Li L, Wang W, Liu Z, Liu N, Wei F, Zheng X, Wang Z.   +8 more
europepmc   +2 more sources

Identification of claudin-3 as an entry factor for rat hepacivirus. [PDF]

Proc Natl Acad Sci U S A
Approximately 58 million people worldwide are believed to be infected with hepatitis C virus (HCV), a major causative agent of chronic liver diseases. Hepacivirus ratti strain rn-1, which was discovered from Rattus norvegicus (Norway rat) and designated ...
Tanaka T, Akaike Y, Kasai H, Yamashita A, Matsuura Y, Moriishi K.   +5 more
europepmc   +2 more sources

Identification of a Novel Hepacivirus in Southeast Asian Shrew (Crocidura fuliginosa) from Yunnan Province, China

Pathogens, 2023
The genus Hepacivirus contains single-stranded positive-sense RNA viruses belonging to the family Flaviviridae, which comprises 14 species. These 14 hepaciviruses have been found in different mammals, such as primates, dogs, bats, and rodents.
Ling Guo, Bei Li, Peiyu Han, Na Dong, Yan Zhu, Fuli Li, Haorui Si, Zhengli Shi, Bo Wang, Xinglou Yang, Yunzhi Zhang   +10 more
doaj   +2 more sources

Evaluation of Risk Determinants and Molecular Characterisation for Non-Primate Hepacivirus Infection in Turkish Horses. [PDF]

Pathogens
The genus Hepacivirus (HCV) has long been a dynamic group, increasing its number by myriads of species collectively referred to as non-primate hepaciviruses (NPHVs).
Atasoy MO, Turan T, Özbek R, Işıdan H, Naggar RFE, Afify AF, Rohaim MA.   +6 more
europepmc   +2 more sources

A Highly Divergent Hepacivirus Identified in Domestic Ducks Further Reveals the Genetic Diversity of Hepaciviruses

Viruses, 2022
Hepaciviruses represent a group of viruses that pose a significant threat to the health of humans and animals. During the last decade, new members of the genus Hepacivirus have been identified in various host species worldwide, indicating the widespread ...
Xue-Lian Zhang, Xin-Yan Yao, Yu-Qian Zhang, Zhi-Hang Lv, Hong Liu, Jing Sun, Jian-Wei Shao   +6 more
doaj   +2 more sources

Viruses in Horses with Neurologic and Respiratory Diseases [PDF]

Viruses, 2019
Metagenomics was used to identify viral sequences in the plasma and CSF (cerobrospinal fluid) of 13 horses with unexplained neurological signs and in the plasma and respiratory swabs of 14 horses with unexplained respiratory signs. Equine hepacivirus and
Eda Altan, Yanpeng Li, Gilberto Sabino-Santos Jr, Vorthon Sawaswong, Samantha Barnum, Nicola Pusterla, Xutao Deng, Eric Delwart   +7 more
doaj   +3 more sources

A Novel Hepacivirus in Wild Rodents from South America [PDF]

Viruses, 2019
The Hepacivirus genus comprises single-stranded positive-sense RNA viruses within the family Flaviviridae. Several hepaciviruses have been identified in different mammals, including multiple rodent species in Africa, Asia, Europe, and North America.
William Marciel de Souza, Marcílio Jorge Fumagalli, Gilberto Sabino-Santos, Felipe Gonçalves Motta Maia, Sejal Modha, Márcio Roberto Teixeira Nunes, Pablo Ramiro Murcia, Luiz Tadeu Moraes Figueiredo   +7 more
doaj   +4 more sources

Discovery of Jogalong virus, a novel hepacivirus identified in a Culex annulirostris (Skuse) mosquito from the Kimberley region of Western Australia.

PLoS ONE, 2020
The discovery of hepaciviruses in non-human hosts has accelerated following the advancement of high-throughput sequencing technology. Hepaciviruses have now been described in reptiles, fish, birds, and an extensive array of mammals.
Simon H Williams, Avram Levy, Rachel A Yates, Nilusha Somaweera, Peter J Neville, Jay Nicholson, Michael D A Lindsay, John S Mackenzie, Komal Jain, Allison Imrie, David W Smith, W Ian Lipkin   +11 more
doaj   +2 more sources

Molecular Determinants of Mouse Adaptation of Rat Hepacivirus

Journal of Virology, 2023
A prophylactic vaccine is required to achieve the World Health Organization’s objective for hepatitis C virus elimination as a serious public health threat.
Raphael Wolfisberg, Kenn Holmbeck, E. Billerbeck, Caroline E. Thorselius, M. N. Batista, U. Fahnøe, Emma A. Lundsgaard, M. J. Kennedy, Louise Nielsen, C. Rice, J. Bukh, T. Scheel   +11 more
semanticscholar   +4 more sources

In vivo and in vitro recombinant systems of a novel variant demonstrate cross-reactive neutralization for the HCV model virus, Norway rat hepacivirus. [PDF]

PLoS Pathog
The lack of immunocompetent animal models severely impedes the development of vaccines against hepatitis C virus (HCV) and researchers have therefore explored the application of surrogate virus models.
Thorselius CE, Kok A, Wolfisberg R, Fahnøe U, Kennedy MJ, Lundsgaard EA, Mikkelsen L, Larsen MK, Murthy S, Trivedi S, Kapoor A, Scheel TKH, Holmbeck K, Bukh J.   +13 more
europepmc   +2 more sources