Results 31 to 40 of about 44,114 (180)

Description of an Equine Hepacivirus Cluster in a Horse Stable in Italy

open access: yesTransboundary and Emerging Diseases, 2023
Equine hepacivirus (EqHV), also known as Hepacivirus A, represents the most closely related genetic homologue of human hepatitis C virus (HCV). Although detected worldwide, limited information on the clinical features of this infection is available and on the mechanisms by which EqHV is transmitted.
Roberta Cardone   +9 more
openaire   +3 more sources

Hepatitis C virus (Flaviviridae: Hepacivirus: Hepacivirus C): regulation of signaling reactions of innate immunity

open access: yesProblems of Virology, 2021
Studying the regulation of signaling reactions of innate immunity by the hepatitis C virus (HCV) will help to reveal the causes of the transition of the acute form of the disease to a chronic course. The molecular mechanisms of activation by HCV RNA of innate immunity receptors TLR and RLR and signal transduction processes leading to the synthesis of ...
openaire   +4 more sources

Mouse models of acute and chronic hepacivirus infection [PDF]

open access: yesScience, 2017
New York City rats provide a gift to virologists Despite the development of curative drugs for hepatitis C virus (HCV) infection, global eradication of HCV will likely require a prophylactic vaccine. Progress toward a vaccine has been impeded by the absence of mouse models suitable for studying the immune response
Eva Billerbeck   +14 more
openaire   +3 more sources

A Novel Genetic Group of Bovine Hepacivirus in Archival Serum Samples from Brazilian Cattle [PDF]

open access: yes, 2017
Hepatitis C virus (HCV) (genus Hepacivirus; family Flaviviridae) is a major human pathogen causing persistent infection and hepatic injury. Recently, emerging HCV-like viruses were described infecting wild animals, such as bats and rodents, and domestic ...
Samuel P. Cibulski   +13 more
core   +2 more sources

Hepacivirus protein length and cleave site sequences.

open access: yes, 2020
Hepacivirus protein length and cleave site sequences.
Komal Jain (432364)   +11 more
core   +1 more source

Identification of claudin-3 as an entry factor for rat hepacivirus. [PDF]

open access: yesProc Natl Acad Sci U S A
Approximately 58 million people worldwide are believed to be infected with hepatitis C virus (HCV), a major causative agent of chronic liver diseases. Hepacivirus ratti strain rn-1, which was discovered from Rattus norvegicus (Norway rat) and designated Norway rat hepacivirus 1 (NRHV1 ...
Tanaka T   +5 more
europepmc   +4 more sources

Tridimensional infiltration of DNA viruses into the host genome shows preferential contact with active chromatin

open access: yesNature Communications, 2018
Whether DNA viruses contact specific regions of host genomes or make random contacts is unclear. Here, the authors use Hi-C and show that HBV cccDNA and Ad5 DNA contact preferentially active chromatin at CpG islands for the former and at transcription ...
Pierrick Moreau   +9 more
doaj   +1 more source

Small RNA fragments derived from multiple RNA classes – the missing element of multi-omics characteristics of the hepatitis C virus cell culture model

open access: yesBMC Genomics, 2017
Background A pool of small RNA fragments (RFs) derived from diverse cellular RNAs has recently emerged as a rich source of functionally relevant molecules.
Paulina Jackowiak   +7 more
doaj   +1 more source

Non-primate hepacivirus infection with apparent hepatitis in a horse — Short communication [PDF]

open access: yes, 2014
Non-primate hepacivirus (NPHV) is a recently identified hepacivirus (family Flaviviridae) in dog and horse; however, the disease associations remain unknown.
Maza, Norbert   +7 more
core   +1 more source

Cure of Hepatitis C

open access: yesActa Médica Portuguesa, 2015
Keywords: Hepacivirus; Hepatitis C, Chronic/drug therapy.
Françoise Roudot-Thoraval
doaj   +1 more source

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