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Hepaciviruses represent a group of viruses that pose a significant threat to the health of humans and animals. During the last decade, new members of the genus Hepacivirus have been identified in various host species worldwide, indicating the widespread ...
Xue-Lian Zhang +6 more
doaj +2 more sources
Viruses in Horses with Neurologic and Respiratory Diseases [PDF]
Metagenomics was used to identify viral sequences in the plasma and CSF (cerobrospinal fluid) of 13 horses with unexplained neurological signs and in the plasma and respiratory swabs of 14 horses with unexplained respiratory signs. Equine hepacivirus and
Eda Altan +7 more
doaj +3 more sources
Dose-Dependent Hepacivirus Infection Reveals Linkage between Infectious Dose and Immune Response
More than 70 million people worldwide are still infected with the hepatitis C virus 30 years after its discovery, underscoring the need for a vaccine. To develop an effective prophylactic vaccine, detailed knowledge of the correlates of protection and an
André Gömer +9 more
doaj +2 more sources
Nonprimate Hepaciviruses in Domestic Horses, United Kingdom [PDF]
Although the origin of hepatitis C virus infections in humans remains undetermined, a close homolog of this virus, termed canine hepacivirus (CHV) and found in respiratory secretions of dogs, provides evidence for a wider distribution of hepaciviruses in
Sinéad Lyons +8 more
doaj +3 more sources
Expanded Diversity and Host Range of Bovine Hepacivirus—Genomic and Serological Evidence in Domestic and Wild Ruminant Species [PDF]
The hepatitis C virus (HCV)-related bovine hepacivirus (BovHepV) can cause acute as well as persistent infections in cattle. The true clinical relevance of the virus is not yet known.
J. Breitfeld +8 more
semanticscholar +2 more sources
Current HIV vaccine strategies are hampered by difficulty with recapitulating heavily mutated broadly neutralizing antibodies. We have previously isolated a highly mutated antibody termed “group C 76-Q13-6F5” (6F5) that uses immunoglobulin heavy chain ...
H. Sojar, S. Baron, M. Hicar
semanticscholar +4 more sources
Postexposure prophylaxis against hepatitis B, hepatitis C and human immunodeficiency virus infection in healthcare workers [PDF]
nema
Vasić Bojan +6 more
doaj +3 more sources
The lack of immunocompetent animal models severely impedes the development of vaccines against hepatitis C virus (HCV) and researchers have therefore explored the application of surrogate virus models.
Caroline E. Thorselius +13 more
semanticscholar +3 more sources
Novel hepacivirus in Asian house shrew, China [PDF]
Hua Guo +13 more
openalex +3 more sources

