Results 41 to 50 of about 16,038 (235)
Immune protection against reinfection with nonprimate hepacivirus [PDF]
Proceedings of the National Academy of Sciences, 2017 Significance Hepatitis C virus (HCV) displays a narrow species tropism severely hampering development of small animal models that are required for vaccine and pathogenesis studies in vivo. The recent discoveries of HCV-related hepaciviruses in diverse hosts offer new opportunities with respect to the development of an immunocompetent animal ...
Stephanie Pfaender +22 more
openalex +5 more sources
Novel hepacivirus in Asian house shrew, China [PDF]
Science China Life Sciences, 2019 Hua Guo +13 more
openalex +3 more sources
Mouse models of acute and chronic hepacivirus infection [PDF]
Science, 2017 New York City rats provide a gift to virologists Despite the development of curative drugs for hepatitis C virus (HCV) infection, global eradication of HCV will likely require a prophylactic vaccine. Progress toward a vaccine has been impeded by the absence of mouse models suitable for studying the immune response to HCV ...
Eva Billerbeck +14 more
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Hallmarks of Hepatitis C Virus in Equine Hepacivirus [PDF]
Journal of Virology, 2014 ABSTRACT Equine hepacivirus (EHcV) has been identified as a closely related homologue of hepatitis C virus (HCV) in the United States, the United Kingdom, and Germany, but not in Asian countries. In this study, we genetically and serologically screened 31 serum samples obtained from Japanese-born domestic horses for EHcV ...
Tomohisa Tanaka +13 more
openalex +3 more sources
Mutational Analysis of the Bovine Hepacivirus Internal Ribosome Entry Site [PDF]
Journal of Virology, 2018 Several members of the family Flaviviridae , including HCV, have adapted cap-independent translation strategies to overcome canonical eukaryotic translation pathways and use cis -acting RNA-elements, designated viral internal ribosome entry sites (IRES), to initiate translation.
Anna Lena Baron +3 more
openalex +4 more sources
Geographical Distribution and Genetic Diversity of Bank Vole Hepaciviruses in Europe [PDF]
, 2021 The development of new diagnostic methods resulted in the discovery of novel hepaciviruses in wild populations of the bank vole (Myodes glareolus, syn. Clethrionomys glareolus). The naturally infected voles demonstrate signs of hepatitis similar to those
Beer, Martin +28 more
core +7 more sources
Natural co‐infection of divergent hepatitis B and C virus homologues in carnivores [PDF]
, 2021 In humans, co-infection of hepatitis B and C viruses (HBV, HCV) is common and aggravates disease outcome. Infection-mediated disease aggravation is poorly understood, partly due to lack of suitable animal models. Carnivores are understudied for hepatitis
Aguilar‐Setién, Álvaro +14 more
core +1 more source
Prevalence of equine hepacivirus infection in Mongolia
Virus Research, 2020 Equine hepacivirus (EHV) belongs to the hepacivirus A and is related to hepatitis C virus (HCV). This virus shows hepatic tropism and is known to chronically infect horses. EHV has been reported from various countries, but the prevalence in Mongolia, where large horse populations are pastured, remains unknown.
Tsendsuren Oyunsuren +5 more
openaire +3 more sources