Keywords: Hepacivirus; Hepatitis C, Chronic/drug therapy.
Françoise Roudot-Thoraval
doaj +1 more source
Treatment of anicteric acute hepatitis C with peginterferon alpha-2a plus ribavirin [PDF]
Background. Hepatitis C virus (HCV) infection is the most frequent cause of chronic hepatitis, cirrhosis, and hepatocellular carcinoma in the world. Acute hepatitis C is the most commonly asymptomatic liver disease with the development of chronic HCV ...
Delić Dragan +4 more
doaj +1 more source
Hepatoma cell density promotes claudin-1 and scavenger receptor BI expression and hepatitis C virus internalization. [PDF]
Hepatitis C virus (HCV) entry occurs via a pH- and clathrin-dependent endocytic pathway and requires a number of cellular factors, including CD81, the tight-junction proteins claudin 1 (CLDN1) and occludin, and scavenger receptor class B member I (SR-BI).
Balfe, Peter +5 more
core +2 more sources
Therapy of acute hepatitis C infection [PDF]
Background. Hepatitis C viral infection is a major cause of chronic hepatitis, liver cirrhosis and hepatocellular carcinoma. The progression of acute to chronic infection occurs in 50-90% of cases.
Đokić Milomir, Begović Vesna
doaj +1 more source
Hepatitis C Virus and Hepatocellular Carcinoma: Pathogenetic Mechanisms and Impact of Direct-Acting Antivirals [PDF]
INTRODUCTION: Globally, between 64 and 103 million people are chronically infected with Hepatitis C virus (HCV), with more than 4.6 million people in the United States and is associated with more than 15.000 deaths annually.
Petruzziello, Arnolfo +5 more
core +1 more source
Presence of a Novel Subtype of Bovine Hepacivirus in China and Expanded Classification of Bovine Hepacivirus Strains Worldwide into 7 Subtypes [PDF]
The newest member of the Hepacivirus genus, bovine hepacivirus (BovHepV), was first identified in cattle in 2015 and is a novel hepacivirus C virus (HCV)-like virus. This virus has been detected in five countries so far and is classified into four subtypes.
Lu, Gang +3 more
openaire +3 more sources
Including osteoprotegerin and collagen IV in a score-based blood test for liver fibrosis increases diagnostic accuracy [PDF]
BACKGROUND: Noninvasive methods for liver fibrosis evaluation in chronic liver diseases have been recently developed, i.e. transient elastography (Fibroscan™) and blood tests (Fibrometer®, Fibrotest®, and Hepascore®).
ANRS HCEP 23 Fibrostar Group +12 more
core +2 more sources
HepacivirusInfection in Domestic Horses, Brazil, 2011–2013
To the Editor: An estimated ≈150 million persons (3% of the world population) are chronically infected with hepatitis C virus (HCV). This virus is the prototype of the genus Hepacivirus and a major cause of liver cirrhosis and hepatocellular carcinoma around the world.
Bernard Salame Gemaque +13 more
openaire +3 more sources
Dissemination of Internal Ribosomal Entry Sites (IRES) Between Viruses by Horizontal Gene Transfer
Members of Picornaviridae and of the Hepacivirus, Pegivirus and Pestivirus genera of Flaviviridae all contain an internal ribosomal entry site (IRES) in the 5′-untranslated region (5′UTR) of their genomes. Each class of IRES has a conserved structure and
Yani Arhab +3 more
doaj +1 more source
Acute and chronic infections with nonprimate hepacivirus in young horses [PDF]
The recently discovered nonprimate hepacivirus (NPHV) naturally infects horses and is the closest known homolog of hepatitis C virus to date. Within a follow-up study acute field infections were monitored in four young Thoroughbred horses until the ages of 12-13 months.
Gather, Theresa +6 more
openaire +4 more sources

