Results 41 to 50 of about 41,094 (191)

The Bank Vole (Clethrionomys glareolus)—Small Animal Model for Hepacivirus Infection

Viruses, 2021
Many people worldwide suffer from hepatitis C virus (HCV) infection, which is frequently persistent. The lack of efficient vaccines against HCV and the unavailability of or limited compliance with existing antiviral therapies is problematic for health ...
Susanne Röhrs, Lineke Begeman, Beate K. Straub, Mariana Boadella, Dennis Hanke, Kerstin Wernike, Stephan Drewes, Bernd Hoffmann, Markus Keller, Jan Felix Drexler, Christian Drosten, Dirk Höper, Thijs Kuiken, Rainer G. Ulrich, Martin Beer   +14 more
doaj   +1 more source

Hallmarks of Hepatitis C Virus in Equine Hepacivirus [PDF]

Journal of Virology, 2014
ABSTRACT Equine hepacivirus (EHcV) has been identified as a closely related homologue of hepatitis C virus (HCV) in the United States, the United Kingdom, and Germany, but not in Asian countries. In this study, we genetically and serologically screened 31 serum samples obtained from Japanese-born domestic horses for EHcV ...
Tomohisa, Tanaka, Hirotake, Kasai, Atsuya, Yamashita, Kaori, Okuyama-Dobashi, Jun, Yasumoto, Shinya, Maekawa, Nobuyuki, Enomoto, Toru, Okamoto, Yoshiharu, Matsuura, Masami, Morimatsu, Noboru, Manabe, Kazuhiko, Ochiai, Kazuto, Yamashita, Kohji, Moriishi   +13 more
openaire   +2 more sources

Hepatitis C virus (Flaviviridae: Hepacivirus: Hepacivirus C): regulation of signaling reactions of innate immunity

Problems of Virology, 2021
Studying the regulation of signaling reactions of innate immunity by the hepatitis C virus (HCV) will help to reveal the causes of the transition of the acute form of the disease to a chronic course. The molecular mechanisms of activation by HCV RNA of innate immunity receptors TLR and RLR and signal transduction processes leading to the synthesis of ...
openaire   +4 more sources

Further Evidence for in Utero Transmission of Equine Hepacivirus to Foals [PDF]

Viruses, 2019
(1) Background: Equine hepacivirus (EqHV), also referred to as non-primate hepacivirus (NPHV), infects horses—and dogs in some instances—and is closely related to hepatitis C virus (HCV) that has infected up to 3% of the world’s human population, causing an epidemic of liver cirrhosis and cancer.
Pronost, Stéphane, Fortier, Christine, Marcillaud-Pitel, Christel, Tapprest, Jackie, Foursin, Marc, Saunier, Bertrand, Pitel, Pierre-Hugues, Paillot, Romain, Hue, Erika   +8 more
openaire   +4 more sources

Description of an Equine Hepacivirus Cluster in a Horse Stable in Italy

Transboundary and Emerging Diseases, 2023
Equine hepacivirus (EqHV), also known as Hepacivirus A, represents the most closely related genetic homologue of human hepatitis C virus (HCV). Although detected worldwide, limited information on the clinical features of this infection is available and on the mechanisms by which EqHV is transmitted.
Roberta Cardone, Alessio Buonavoglia, Gianvito Lanave, Violetta Iris Vasinioti, Valentina Mininni, Eleonora Lorusso, Nicola Decaro, Vito Martella, Gabriella Elia, Georgia Diakoudi   +9 more
openaire   +3 more sources

Tridimensional infiltration of DNA viruses into the host genome shows preferential contact with active chromatin

Nature Communications, 2018
Whether DNA viruses contact specific regions of host genomes or make random contacts is unclear. Here, the authors use Hi-C and show that HBV cccDNA and Ad5 DNA contact preferentially active chromatin at CpG islands for the former and at transcription ...
Pierrick Moreau, Axel Cournac, Gianna Aurora Palumbo, Martial Marbouty, Shogofa Mortaza, Agnes Thierry, Stefano Cairo, Marc Lavigne, Romain Koszul, Christine Neuveut   +9 more
doaj   +1 more source

Small RNA fragments derived from multiple RNA classes – the missing element of multi-omics characteristics of the hepatitis C virus cell culture model

BMC Genomics, 2017
Background A pool of small RNA fragments (RFs) derived from diverse cellular RNAs has recently emerged as a rich source of functionally relevant molecules.
Paulina Jackowiak, Anna Hojka-Osinska, Anna Philips, Agnieszka Zmienko, Lucyna Budzko, Patrick Maillard, Agata Budkowska, Marek Figlerowicz   +7 more
doaj   +1 more source

Therapy of chronic hepatitis C: Virologic response monitoring [PDF]

Vojnosanitetski Pregled, 2010
Background/Aim. Virological testing is considered to be essential in the management of hepatitis C virus (HCV) infection in order to diagnose infection, and, most importantly, as a quide for treatment decisions and assess the virological response to ...
Kuljić-Kapulica Nada, Jovanović Dragutin, Savić Dejana, Ristanović Elizabeta, Nožić Darko, Rajić Radmila   +5 more
doaj   +1 more source

Cure of Hepatitis C

Acta Médica Portuguesa, 2015
Keywords: Hepacivirus; Hepatitis C, Chronic/drug therapy.
Françoise Roudot-Thoraval
doaj   +1 more source

Treatment of anicteric acute hepatitis C with peginterferon alpha-2a plus ribavirin [PDF]

Vojnosanitetski Pregled, 2005
Background. Hepatitis C virus (HCV) infection is the most frequent cause of chronic hepatitis, cirrhosis, and hepatocellular carcinoma in the world. Acute hepatitis C is the most commonly asymptomatic liver disease with the development of chronic HCV ...
Delić Dragan, Nešić Zorica I., Prostran Milica Š., Simonović Jasmina, Švirtlih Neda   +4 more
doaj   +1 more source