Results 61 to 70 of about 20,741 (247)

Supporting children with genetic syndromes in the classroom: the example of 22q deletion syndrome [PDF]

, 2013
An increasing number of children are likely to have a known genetic cause for their special educational needs. One such genetic condition is 22q11.2 deletion syndrome (22qDS), a genetic syndrome associated with early speech and language difficulties ...
Reilly, C, Stedman, L
core   +1 more source

Small RNA fragments derived from multiple RNA classes – the missing element of multi-omics characteristics of the hepatitis C virus cell culture model

BMC Genomics, 2017
Background A pool of small RNA fragments (RFs) derived from diverse cellular RNAs has recently emerged as a rich source of functionally relevant molecules.
Paulina Jackowiak, Anna Hojka-Osinska, Anna Philips, Agnieszka Zmienko, Lucyna Budzko, Patrick Maillard, Agata Budkowska, Marek Figlerowicz   +7 more
doaj   +1 more source

Identification of GBV-D, a novel GB-like flavivirus from Old World frugivorous Bats (Pteropus giganteus) in Bangladesh [PDF]

, 2010
Bats are reservoirs for a wide range of zoonotic agents including lyssa-, henipah-, SARS-like corona-, Marburg-, Ebola-, and astroviruses. In an effort to survey for the presence of other infectious agents, known and unknown, we screened sera from 16 ...
Briese, Thomas, Conlan, Sean, Daszak, Peter, Egholm, Michael, Epstein, Jonathan H., Hossain, M. Jahangir, Hutchison, Stephen K., Jabado, Omar J., Khan, Shahneaz Ali, Lipkin, W. Ian, Luby, Stephen P., Quan, Phuong-Lan, Street, Craig, Verdugo, Dawn   +13 more
core   +3 more sources

Severe Acute Hepatitis Outbreaks Associated with a Novel Hepacivirus in Rhizomys pruinosus in Hainan, China

Journal of Virology, 2022
Members of the genus Hepacivirus have a broad host range, with at least 14 species identified, but none is highly pathogenic to its host except for hepatitis C virus, which causes severe liver diseases in humans.
Jianfeng Jiang, Yuqing Hao, B. He, Lianhua Su, Xuezheng Li, Xiangxiang Liu, Chuanwei Chen, Li-juan Chen, Zihan Zhao, S. Mi, Xuming Deng, W. Gong, C. Tu   +12 more
semanticscholar   +1 more source

Tridimensional infiltration of DNA viruses into the host genome shows preferential contact with active chromatin

Nature Communications, 2018
Whether DNA viruses contact specific regions of host genomes or make random contacts is unclear. Here, the authors use Hi-C and show that HBV cccDNA and Ad5 DNA contact preferentially active chromatin at CpG islands for the former and at transcription ...
Pierrick Moreau, Axel Cournac, Gianna Aurora Palumbo, Martial Marbouty, Shogofa Mortaza, Agnes Thierry, Stefano Cairo, Marc Lavigne, Romain Koszul, Christine Neuveut   +9 more
doaj   +1 more source

Cure of Hepatitis C

Acta Médica Portuguesa, 2015
Keywords: Hepacivirus; Hepatitis C, Chronic/drug therapy.
Françoise Roudot-Thoraval
doaj   +1 more source

Dissemination of Internal Ribosomal Entry Sites (IRES) Between Viruses by Horizontal Gene Transfer

Viruses, 2020
Members of Picornaviridae and of the Hepacivirus, Pegivirus and Pestivirus genera of Flaviviridae all contain an internal ribosomal entry site (IRES) in the 5′-untranslated region (5′UTR) of their genomes. Each class of IRES has a conserved structure and
Yani Arhab, Alexander G. Bulakhov, Tatyana V. Pestova, Christopher U.T. Hellen   +3 more
doaj   +1 more source

Significant down-regulation of growth hormone receptor expression revealed as a new unfavorable prognos- tic factor in hepatitis C virus-related hepatocellular carcinoma [PDF]

Clinical and Molecular Hepatology, 2021
Background/Aims Growth hormone (GH) is the main regulator of somatic growth, metabolism, and gender dimorphism in the liver. GH receptor (GHR) signaling in cancer is derived from a large body of evidence, although the GHR signaling pathway involved in ...
Ching-Chih Lin, Ta-Wei Liu, Ming-Lun Yeh, Yi-Shan Tsai, Pei-Chien Tsai, Chung-Feng Huang, Jee-Fu Huang, Wan-Long Chuang, Chia-Yen Dai, Ming-Lung Yu   +9 more
doaj   +1 more source

Hepatitis C Virus and Hepatocellular Carcinoma: Pathogenetic Mechanisms and Impact of Direct-Acting Antivirals [PDF]

, 2018
INTRODUCTION: Globally, between 64 and 103 million people are chronically infected with Hepatitis C virus (HCV), with more than 4.6 million people in the United States and is associated with more than 15.000 deaths annually.
Petruzziello, Arnolfo, Pinacchio, Claudia, Scheri, Giuseppe Corano, Schietroma, Ivan, Statzu, Maura, Vullo, Vincenzo   +5 more
core   +1 more source

Genome Characterization and Phylogenetic Analysis of Bovine Hepacivirus in Inner Mongolia, Northeastern China

Zoonoses, 2022
Bovine hepacivirus (BovHepV) is a new member of the genus Hepacivirus in the family Flaviviridae, which has been detected in cattle in more than seven countries.
Zi-Jiang Liu, Liang Li, Yu Guo, Wenbo Xu, Yongxu Yuan, Xiaojie Liang, Wei Wang, Yinghua Zhao, Liyan Sui, Xian-min Feng, F. Wei, QUAN LIU, Zedong Wang   +12 more
semanticscholar   +1 more source