Results 251 to 260 of about 40,174 (273)

Characterization of Insulin-like Growth Factor Binding Protein-3 (IGFBP-3) interaction with the Bovine Aortic Endothelial (BAE) cell surface : Examination of the Role of Heparan Sulfate Proteoglycans (HSPG).

, 1998
Nirav Parghi, Kimberly E. Forsten, W. L. Conger   +2 more
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The Role of the Cell Surface Heparan Sulfate Proteoglycan Syndecan-3 In Breast Cancer Pathophysiology

Lena Habenicht, Nourhan Hassan, Nancy Adriana Espinoza‐Sánchez, Balázs Győrffy, Lars Hanker, Burkhard Greve, Martin Götte   +6 more
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Cellular Catabolism of Heparan Sulfate Proteoglycans.

Trends in Glycoscience and Glycotechnology, 1998
openaire   +2 more sources

Polymeric carriers in non-viral gene delivery: a study of physicochemical properties and biological activity in human RPE cell line (Polymeeriset kuljettimet geeninsiirrossa: tutkimus fysikaalis-kemiallisista ominaisuuksista ja biologisesta aktiivisuudesta ihmisen retinan pigmentti-epiteelisoluissa) [PDF]

Männistö, Marjo
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Heparan Sulfate Proteoglycans in Diabetes

Seminars in Thrombosis and Hemostasis, 2021
AbstractDiabetes is a complex disorder responsible for the mortality and morbidity of millions of individuals worldwide. Although many approaches have been used to understand and treat diabetes, the role of proteoglycans, in particular heparan sulfate proteoglycans (HSPGs), has only recently received attention.
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Development of Molecules Antagonizing Heparan Sulfate Proteoglycans

Seminars in Thrombosis and Hemostasis, 2021
AbstractHeparan sulfate proteoglycans (HSPGs) occur in almost every tissue of the human body and consist of a protein core, with covalently attached glycosaminoglycan polysaccharide chains. These glycosaminoglycans are characterized by their polyanionic nature, due to sulfate and carboxyl groups, which are distributed along the chain.
Tanja, Gerlza, Christina, Trojacher, Nikola, Kitic, Tiziana, Adage, Andreas J, Kungl   +4 more
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Heparan Sulfate Proteoglycans in Amyloidosis

2010
Amyloidosis is a generic term for a group of diseases characterized by deposits in different organ systems of insoluble materials composed mainly of distinct fibrillar proteins named amyloid. Besides amyloid, heparan sulfate proteoglycan (HSPG), is commonly found in most amyloid deposits, suggesting that HS/HSPG may be functionally involved in the ...
Xiao, Zhang, Jin-Ping, Li
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Heparan Sulfate Proteoglycans

1999
Abstract Heparan sulfate proteoglycans (HSPGs)1 are highly charged macromolecules consisting of different core proteins with covalently linked heparan sulfate chains (HS) of varying monosaccharide sequence. These molecules are involved in a multitude of biologic processes including regulation of mesoderm induction, extension of neurites,
Nicholas W Shworak, Robert D Rosenberg
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Integral membrane heparan sulfate proteoglycans

The FASEB Journal, 1993
Heparan sulfate is a regulatory polysaccharide. It modulates specific growth factor‐receptor interactions, accelerates the formation of specific proteinase‐proteinase inhibitor complexes, and mediates interactions of the cell surface with several enzymes and structural proteins.
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Alzheimer s disease and heparan sulfate proteoglycan

Frontiers in Bioscience, 1998
Alzheimer's disease (AD) is a debilitating neurodegenerative disorder. Cardinal histopathologic changes of AD are neurofibrillary tangles (NFTs) and deposits of beta-amyloid protein (A-beta) in the form of neuritic plaques (NPs). Several different mutations found in patients with familial AD have been demonstrated to increase A-beta production ...
K, Fukuchi, M, Hart, L, Li
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