Glycoinformatic Profiling of Label-Free Intact Heparan Sulfate Oligosaccharides. [PDF]
Maciej-Hulme ML +14 more
europepmc +1 more source
The role of extracellular superoxide dismutase on the function of endothelium [PDF]
Καραμπατζάκης, Αλέξανδρος
core
A Novel Series of Synthetic Heparin-Mimetics-Itaconic Acid-Containing Copolymers for Targeting Tumor Cell Coagulability and Metastasis. [PDF]
Nekipelov K +12 more
europepmc +1 more source
A tellurium-based small compound ameliorates tumor metastasis by downregulating heparanase expression. [PDF]
Liu YH +6 more
europepmc +1 more source
Role of the endothelial cell glycocalyx in sepsis-induced acute kidney injury. [PDF]
Wang Y, Zhang Z, Qu X, Zhou G.
europepmc +1 more source
Correction: Tumor- and host-derived heparanase-2 (Hpa2) attenuates tumorigenicity: role of Hpa2 in macrophage polarization and BRD7 nuclear localization. [PDF]
Soboh S +12 more
europepmc +1 more source
Opposing Functions of Heparanase-1 and Heparanase-2 in Cancer Progression [PDF]
Heparanase, the sole heparan sulfate (HS)-degrading endoglycosidase, regulates multiple biological activities that enhance tumor growth, metastasis, angiogenesis, and inflammation. Heparanase accomplishes this by degrading HS and thereby regulating the bioavailability of heparin-binding proteins; priming the tumor microenvironment; mediating tumor-host
Israel Vlodavsky +2 more
exaly +3 more sources
Heparanase in glomerular diseases [PDF]
Heparanase is an endo-beta(1-4)-D-glucuronidase that degrades heparan sulfate (HS) polysaccharide side chains. The role of heparanase in metastasis, angiogenesis, and inflammation has been established. Recent data suggest a role for heparanase in several proteinuric diseases and an increased glomerular heparanase expression is associated with loss of ...
J H Berden
exaly +5 more sources
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Heparanase procoagulant activity
Thrombosis Research, 2012Heparanase that was cloned from and is abundant in the placenta is implicated in cell invasion, tumor metastasis and angiogenesis. We have recently demonstrated that heparanase may also affect the hemostatic system in a non-enzymatic manner. Heparanase was shown to up-regulate tissue factor (TF) expression and interact with tissue factor pathway ...
Yona, Nadir, Benjamin, Brenner
openaire +2 more sources

