Results 191 to 200 of about 11,910 (223)
Some of the next articles are maybe not open access.
Synthesis of simple heparanase substrates
Organic & Biomolecular Chemistry, 2011Heparanase degrades heparan sulfate (HS) chains on proteoglycans; elevated levels of heparanase expression correlate with tumour cell metastatic potential and vascularity, and reduced post-operative survival of cancer patients. Consequently, heparanase expression is considered a biomarker for cancer detection.
Pearson, Andrew G +3 more
openaire +3 more sources
Heparanase improves mouse embryo implantation
Fertility and Sterility, 2005To improve mouse embryonic implantation by recombinant heparanase supplementation. Heparanase, an endoglycosidase-degrading heparan sulfate proteoglycan, may have a role in embryonic implantation because of its enzymatic, angiogenic, and adhesive properties. Increasing endometrial receptivity could improve one of the most difficult pathologies in human
Ariel, Revel +7 more
openaire +2 more sources
Heparanase coagulation and cancer progression
Best Practice & Research Clinical Haematology, 2009Heparanase is an endo-beta-D-glucuronidase capable of cleaving heparan sulphate (HS) side chains of heparan sulphate proteoglycans on cell surfaces and the extracellular matrix; activity that is strongly implicated in tumour metastasis and angiogenesis.
Yona, Nadir, Benjamin, Brenner
openaire +2 more sources
The FASEB Journal, 2007
Heparanase is a mammalian endo‐β‐D‐glucuronidase capable of cleaving HS side chains at a limited number of sites, activity that is strongly implicated in tumor metastasis, neovascularization, inflammation, and autoimmunity. Clinically, up‐regulation of heparanase mRNA and protein expression has been documented in a variety of ...
Svetlana, Gingis-Velitski +3 more
openaire +2 more sources
Heparanase is a mammalian endo‐β‐D‐glucuronidase capable of cleaving HS side chains at a limited number of sites, activity that is strongly implicated in tumor metastasis, neovascularization, inflammation, and autoimmunity. Clinically, up‐regulation of heparanase mRNA and protein expression has been documented in a variety of ...
Svetlana, Gingis-Velitski +3 more
openaire +2 more sources
Neuronal expression of heparanase 1 and heparanase 2
2014Conference Theme: A Century of Advances in Physiology, Biophysics and ...
Ma, CW +4 more
openaire +1 more source
Heparanase in the Coagulation System
2020The hemostatic cascade is initiated by the transmembrane coagulation protein - tissue factor (TF) and eventuates in fibrin formation. Heparanase protein was demonstrated to directly enhance TF activity resulting in increased activation of the coagulation system.
openaire +2 more sources
Heparanase 1 and Heparanase 2 expression in Hippocampal Neurons
2014Poster presentation - Theme 5 ...
Shum, DKY, Lau, TWY
openaire +1 more source
Heparanase: From basic research to therapeutic applications in cancer and inflammation
Drug Resistance Updates, 2016Israel Vlodavsky +2 more
exaly
Role of heparanase in tumor progression: Molecular aspects and therapeutic options
Seminars in Cancer Biology, 2020Valentina Masola +2 more
exaly