Results 1 to 10 of about 724,197 (388)
Nature Communications, 2019 Heparin-induced thrombocytopenia/thrombosis (HIT) is a serious immune reaction to heparins, characterized by thrombocytopenia and often severe thrombosis with high morbidity and mortality. HIT is mediated by IgG antibodies against heparin/platelet factor
Feng Yan +2 more
exaly +2 more sources
The anti-cancer properties of heparin and its derivatives: a review and prospect
Cell Adhesion & Migration, 2020 Heparin, including unfractionated heparin (UFH), low-molecular-weight heparin (LMWH) and heparin derivatives, are commonly used in venous thromboembolism treatment and reportedly have beneficial effects on cancer survival.
Sai-Nan Ma +8 more
doaj +2 more sources
CLINICAL PRACTICE. Heparin-Induced Thrombocytopenia. [PDF]
New England Journal of Medicine, 2015 Heparin-induced thrombocytopenia (HIT), typically occurring in the second week of heparin therapy, is an antibody-mediated adverse drug reaction associated with increased thrombotic risk. The most important antigens are located on platelet factor 4 (PF4)/heparin complexes.
A. Greinacher
semanticscholar +8 more sources
A heparin-mimicking polymer conjugate stabilizes basic fibroblast growth factor [PDF]
Nature Chemistry, 2013 Basic fibroblast growth factor (bFGF) is a protein that plays a crucial role in diverse cellular functions, from wound healing to bone regeneration.
Joseph A Loo, Heather D Maynard
exaly +3 more sources
Effect of fibronectin on the binding of antithrombin III to immobilized heparin [PDF]
, 1996 An objective of this research is to verify the mechanism of anticoagulant activity of surface-immobilized heparin in the presence of plasma proteins.
Byun, Youngro +3 more
core +25 more sources
JAMA Internal Medicine, 2021 Importance Hospitalized patients with COVID-19 are at risk for venous and arterial thromboembolism and death. Optimal thromboprophylaxis dosing in high-risk patients is unknown. Objective To evaluate the effects of therapeutic-dose low-molecular-weight
A. Spyropoulos +23 more
semanticscholar +1 more source
British medical journal, 2021 Objective To evaluate the effects of therapeutic heparin compared with prophylactic heparin among moderately ill patients with covid-19 admitted to hospital wards. Design Randomised controlled, adaptive, open label clinical trial. Setting 28 hospitals in
M. Sholzberg +226 more
semanticscholar +1 more source
Thrombosis Journal, 2021 Background This is a review article on heparin-induced thrombocytopenia, an adverse effect of heparin therapy, and vaccine-induced immune thrombotic thrombocytopenia, occurring in some patients administered certain coronavirus vaccines.
Payel Datta +3 more
doaj +1 more source
Influence of different levels of heparin and antithrombin Ⅲ on human coagulation factor Ⅸ activity
Zhongguo shuxue zazhi, 2022 Objective To study the effect of different concentrations of heparin, ATⅢ or a mixture of heparin and antithrombin Ⅲ (ATⅢ) (1∶1)on the activity of human coagulation factor Ⅸ (FⅨ).
Changyong JIAN +5 more
doaj +1 more source