Effect of fibronectin on the binding of antithrombin III to immobilized heparin [PDF]
, 1996 An objective of this research is to verify the mechanism of anticoagulant activity of surface-immobilized heparin in the presence of plasma proteins.
Byun, Youngro +3 more
core +42 more sources
Nebulized heparin in burn patients with inhalation trauma : safety and feasibility [PDF]
, 2020 Background: Pulmonary hypercoagulopathy is intrinsic to inhalation trauma. Nebulized heparin could theoretically be beneficial in patients with inhalation injury, but current data are conflicting.
Binnekade, Jan M. +17 more
core +2 more sources
The ISFET based heparin sensor with a monolayer of protamine as affinity ligand [PDF]
, 1995 The ion-step measuring method was used to determine absolute heparin concentrations in PBS and blood plasma with a Ta2O5 ISFET on to which a monolayer of protamine had been immobilized. Heparin is a highly negatively charged polysaccharide, which is used
Bergveld, P. +2 more
core +2 more sources
pH-Sensitive Chitosan–Heparin Nanoparticles for Effective Delivery of Genetic Drugs into Epithelial Cells [PDF]
, 2019 Chitosan has been extensively studied as a genetic drug delivery platform. However, its efficiency is limited by the strength of DNA and RNA binding.
Korzhikov-Vlakh, Viktor +7 more
core +1 more source
Design of a new type of coating for the controlled release of heparin [PDF]
, 1997 Thrombus formation at the surface of blood contacting devices can be prevented by local release of heparin. Preferably, the release rate should be constant for prolonged periods of time.
Engbers, G.H.M. +4 more
core +3 more sources
Interaction of antithrombin III with surface-immobilized albumin-heparin conjugates [PDF]
, 1995 The interaction between antithrombin III (ATIII) and albumin-heparin conjugates covalently coupled onto carboxylated polystyrene beads either in buffer containing albumin or in plasma was studied using 14C-labeled ATIII.
Delden, C.J. van +2 more
core +2 more sources
Release of macromolecules from albumin-heparin microspheres [PDF]
, 1992 Hydrophilic microspheres based on albumin-heparin conjugates have been prepared as a macromolecular delivery system. The soluble albumin-heparin conjugate was synthesized and crosslinked in a water-in-oil emulsion with glutaraldehyde to form microspheres
Bae, You Han +5 more
core +2 more sources
Albumin-heparin microspheres as carriers for cytostatic agents [PDF]
, 1990 Much work has been done on adriamycin-loaded albumin microspheres (Alb-MS) for chemoembolization [1–4], the rationale being that site-specific drug delivery may increase the therapeutic efficacy of the drug. Alb-Ms are being investigated because of their
Bae, Y.H. +6 more
core +2 more sources
Lipolysis generates platelet dysfunction after in vivo heparin administration [PDF]
, 2002 Heparin, when administered to patients undergoing operations using cardiopulmonary bypass, induces plasma changes that gradually impair platelet macroaggregation, but heparinization of whole blood in vitro does not have this effect.
Belcher, P.R. +5 more
core +1 more source
Heparin release from thermosensitive hydrogels [PDF]
, 1992 Thermosensitive hydrogels (TSH) were synthesized and investigated as heparin releasing polymers for the prevention of surface induced thrombosis. TSH were synthesized with N-isopropyl acrylamide (NiPAAm) copolymerized with butyl methacrylate (BMA ...
Bae, You Han +5 more
core +3 more sources