Results 11 to 20 of about 1,309 (162)
Real‐World Experience with a Human Fibrinogen Concentrate: Clinical Data from Adult and Pediatric Patients Requiring Fibrinogen for Bleeding Control and Prevention
The Journal of Clinical Pharmacology, Volume 63, Issue 11, Page 1186-1196, November 2023., 2023 Abstract
Human fibrinogen concentrate (Fibryga) received temporary approval for fibrinogen replacement therapy in France (2017), with subsequent full approval for congenital and acquired hypofibrinogenemia. We evaluated real‐world use for on‐demand treatment of bleeding and prophylaxis to enhance our knowledge on fibrinogen concentrate as an option for Francois Stéphan, Loriane Gutermann, Stéphanie Bourget, Sarah Djabarouti, Johanna Berdugo, Yann Fardini, Pierre Clerson, Guillaume Hébert, Chafké Belmokhtar +8 morewiley +1 more sourceDecompressive surgery in cerebral venous sinus thrombosis due to vaccine‐induced immune thrombotic thrombocytopenia
European Journal of Neurology, Volume 30, Issue 5, Page 1335-1345, May 2023., 2023 Abstract Background and purpose
Cerebral venous sinus thrombosis due to vaccine‐induced immune thrombotic thrombocytopenia (CVST‐VITT) is an adverse drug reaction occurring after severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) vaccination.Katarzyna Krzywicka, Diana Aguiar de Sousa, Charlotte Cordonnier, Felix J. Bode, Thalia S. Field, Dominik Michalski, Johann Pelz, Mona Skjelland, Markus Wiedmann, Julian Zimmermann, Matthias Wittstock, Bruno Zanotti, Alfonso Ciccone, Monica Bandettini di Poggio, Afshin Borhani‐Haghighi, Sophie Chatterton, Avinash Aujayeb, Annemie Devroye, Vanessa Dizonno, Thomas Geeraerts, Fabrizio Giammello, Albrecht Günther, Nasli R. Ichaporia, Timothy Kleinig, Espen S. Kristoffersen, Robin Lemmens, Emmanuel De Maistre, Zahra Mirzaasgari, Jean‐Francois Payen, Jukka Putaala, Marco Petruzzellis, Nicolas Raposo, Elyar Sadeghi‐Hokmabadi, Silvia Schoenenberger, Meenakshisundaram Umaiorubahan, Padmavathy N Sylaja, Anita van de Munckhof, Mayte Sánchez van Kammen, Erik Lindgren, Katarina Jood, Adrian Scutelnic, Mirjam R. Heldner, Sven Poli, Marieke J. H. A. Kruip, Antonio Arauz, Adriana B. Conforto, Sanjith Aaron, Saskia Middeldorp, Turgut Tatlisumak, Marcel Arnold, Jonathan M. Coutinho, José M. Ferro, Cerebral Venous Sinus Thrombosis with Thrombocytopenia Syndrome Study Group +52 morewiley +1 more sourceNeurological symptoms and complications in predominantly hospitalized COVID‐19 patients: Results of the European multinational Lean European Open Survey on SARS‐Infected Patients (LEOSS)
European Journal of Neurology, Volume 28, Issue 12, Page 3925-3937, December 2021., 2021 We retrospectively analyzed data from 6537 predominantly hospitalized COVID‐19 patients registered in the European multinational Lean European Open Survey on SARS‐Infected Patients (LEOSS) registry between January 2020 and February 2021. Common neurological symptoms were excessive tiredness (28.0%), headache (18.5%), nausea/emesis (16.6%), muscular ...Nina N. Kleineberg, Samuel Knauss, Eileen Gülke, Hans O. Pinnschmidt, Carolin E. M. Jakob, Paul Lingor, Kerstin Hellwig, Achim Berthele, Günter Höglinger, Gereon R. Fink, Matthias Endres, Christian Gerloff, Christine Klein, Melanie Stecher, Annika Y. Classen, Siegbert Rieg, Stefan Borgmann, Frank Hanses, Maria M. Rüthrich, Martin Hower, Lukas Tometten, Martina Haselberger, Christiane Piepel, Uta Merle, Sebastian Dolff, Christian Degenhardt, Björn‐Erik O. Jensen, Maria J. G. T. Vehreschild, Johanna Erber, Christiana Franke, Clemens Warnke, the LEOSS Study Group +31 morewiley +1 more sourceUmbilical cord mesenchymal stem cells for COVID‐19 acute respiratory distress syndrome: A double‐blind, phase 1/2a, randomized controlled trial
STEM CELLS Translational Medicine, Volume 10, Issue 5, Page 660-673, May 2021., 2021 Abstract
Acute respiratory distress syndrome (ARDS) in COVID‐19 is associated with high mortality. Mesenchymal stem cells are known to exert immunomodulatory and anti‐inflammatory effects and could yield beneficial effects in COVID‐19 ARDS. The objective of this study was to determine safety and explore efficacy of umbilical cord mesenchymal stem cell (Giacomo Lanzoni, Elina Linetsky, Diego Correa, Shari Messinger Cayetano, Roger A. Alvarez, Dimitrios Kouroupis, Ana Alvarez Gil, Raffaella Poggioli, Phillip Ruiz, Antonio C. Marttos, Khemraj Hirani, Crystal A. Bell, Halina Kusack, Lisa Rafkin, David Baidal, Andrew Pastewski, Kunal Gawri, Clarissa Leñero, Alejandro M. A. Mantero, Sarah W. Metalonis, Xiaojing Wang, Luis Roque, Burlett Masters, Norma S. Kenyon, Enrique Ginzburg, Xiumin Xu, Jianming Tan, Arnold I. Caplan, Marilyn K. Glassberg, Rodolfo Alejandro, Camillo Ricordi +30 morewiley +1 more sourceRecovery from Liver Failure and Fibrosis in a Rat Portacaval Anastomosis Model after Neurointermediate Pituitary Lobectomy
Journal of Immunology Research, Volume 2021, Issue 1, 2021., 2021 Liver diseases, including cirrhosis, viral hepatitis, and hepatocellular carcinoma, account for approximately two million annual deaths worldwide. They place a huge burden on the global healthcare systems, compelling researchers to find effective treatment for liver fibrosis‐cirrhosis.Martín Muñoz-Ortega, Noé Macías-Segura, Javier Ventura-Juárez, Manuel Enrique Ávila-Blanco, Leonardo D. Ponce-Damian, Daniel González-Blas, Esperanza Sánchez-Alemán, Andrés Quintanar-Stephano, Charles Elias Assmann +8 morewiley +1 more sourceSingle‐molecule mechanochemical characterization of E. coli pol III core catalytic activity
Protein Science, Volume 26, Issue 7, Page 1413-1426, July 2017., 2017 Abstract
Pol III core is the three‐subunit subassembly of the E. coli replicative DNA polymerase III holoenzyme. It contains the catalytic polymerase subunit α, the 3′ → 5′ proofreading exonuclease ε, and a subunit of unknown function, θ. We employ optical tweezers to characterize pol III core activity on a single DNA substrate.M. Nabuan Naufer, David A. Murison, Ioulia Rouzina, Penny J. Beuning, Mark C. Williams +4 morewiley +1 more sourceInvestigation of Luminescence Characteristics of Osmium(II) Complexes in the Presence of Heparin Polyanions
International Journal of Analytical Chemistry, Volume 2013, Issue 1, 2013., 2013 The luminescence characteristics of six osmium carbonyl complexes with phenanthroline (phen) or bipyridine (bpy) and pyridine (py), 4‐phenylpyridine (4‐phpy), or triphenylphosphine (PPh3) complexes in the presence of polyanion heparin were studied in both ethanol and aqueous solutions.Yixi Xie, Yu Lei, Shalini Shah, Hao Wu, Jian Wu, Elise Megehee, Enju Wang, John P. Hart +7 morewiley +1 more source