Targeting the muscle for the treatment and prevention of hepatic encephalopathy [PDF]
, 2016 Muscle mass loss or sarcopenia is a principle component of malnutrition which prevails in 65–90% of patients with end-stage liver disease [1]. Intuitively, the roots of malnutrition play a precipitating role in muscle catabolism.
Bémeur, Chantal +2 more
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Frailty is independently associated with increased hospitalisation days in patients on the liver transplant waitlist [PDF]
, 2016 AIM: To investigate the impact of physical frailty on risk of hospitalisation in cirrhotic patients on the liver transplant waitlist. METHODS: Cirrhotics listed for liver transplantation at a single centre underwent frailty assessments using the Fried ...
Dodge, Jennifer L +3 more
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Hepatic encephalopathy: A review
Annals of Hepatology, 2003 Hepatic encephalopathy (HE) is a complication that presents in as many as 28% of patients with cirrhosis, and reported up to ten years after the diagnosis of cirrhosis. Commonly, it is observed in patients with severe hepatic failure and is characterized
Javier Lizardi-Cervera, MD +3 more
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Xenogeneic, extracorporeal liver perfusion in primates improves the ratio of branched-chain amino acids to aromatic amino acids (Fischer's ratio) [PDF]
, 1999 In fulminant hepatic failure (FHF), the development of hepatic encephalopathy is associated with grossly abnormal concentrations of plasma amino acids (PAA).
Hammer, C. +7 more
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Assessment of Serum Biochemical Changes in Hepatic Encephalopathy
Pakistan Armed Forces Medical Journal, 2022 Objective: To analyze the association of various biochemical changes with different grades of hepatic encephalopathy among patients of hepatitis C-related decompensated liver disease presenting at Pak Emirates Military Hospital. Rawalpindi, Pakistan.
Amna Rauf, Sidra Rauf
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No effect of albumin infusion on the prevention of hepatic encephalopathy after transjugular intrahepatic portosystemic shunt [PDF]
, 2015 Hepatic encephalopathy (HE) is a major problem in patients submitted to TIPS. Previous studies identified low albumin as a factor associated to post-TIPS HE.
Frieri, Camilla +8 more
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Sarcopenia from mechanism to diagnosis and treatment in liver disease [PDF]
, 2016 Sarcopenia or loss of skeletal muscle mass is the major component of malnutrition and is a frequent complication in cirrhosis that adversely affects clinical outcomes.
Dasarathy, Srinivasan, MERLI, Manuela
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Frailty and the Burden of Concurrent and Incident Disability in Patients With Cirrhosis: A Prospective Cohort Study. [PDF]
, 2020 Frailty results from the chronic effects of malnutrition and muscle wasting in patients with cirrhosis. It is well-established that frailty is strongly associated with mortality in this population.
Covinsky, Kenneth E +4 more
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Features of encephalopathy diagnosis in patients with portal hypertension syndrome
Gastroenterologìa, 2017 Background. Hepatic encephalopathy is a pathological change in the brain functions of non-inflammatory origin, which is manifested by a syndrome of secondary neurological and cognitive disorders caused by a set of deep metabolic disorders, as a result of
Yu.M. Stepanov +2 more
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