Results 41 to 50 of about 157,614 (311)

Development of NASH in Obese Mice is Confounded by Adipose Tissue Increase in Inflammatory NOV and Oxidative Stress [PDF]

open access: yes, 2018
Aim. Nonalcoholic steatohepatitis (NASH) is the consequence of insulin resistance, fatty acid accumulation, oxidative stress, and lipotoxicity.We hypothesize that an increase in the inflammatory adipokine NOV decreases antioxidant Heme Oxygenase 1 (HO- 1)
Abraham, Nader G.   +13 more
core   +1 more source

Impact of Hepatic Steatosis on the Antiviral Effects of PEG-IFNα-2a in Patients with Chronic Hepatitis B and the Associated Mechanism

open access: yesGastroenterology Research and Practice, 2020
Objective. To investigate the risk factors for hepatic steatosis in chronic hepatitis B (CHB), to determine its correlation with liver necroinflammation and fibrosis and response to peginterferon alpha-2a (PEG-IFNα-2a) antiviral therapy, and to explore ...
Huiqing Liang   +14 more
doaj   +1 more source

Steatosis and hepatitis C [PDF]

open access: yesGastroenterology Report, 2015
Hepatitis C virus (HCV) infection is a common liver disease worldwide with a high rate of chronicity (75-80%) in infected individuals. The chronic form of HCV leads to steatosis, cirrhosis and hepatocellualr carcinoma. Steatosis is prevalent in HCV patients (55%) due to a combination of viral factors (effect of viral proteins on some of the ...
Modaresi Esfeh, Jamak   +1 more
openaire   +2 more sources

GSH Attenuates Organ Injury and Improves Function after Transplantation of Fatty Livers [PDF]

open access: yes, 2010
Ischemia-reperfusion injury (IRI) is increased after transplantation of steatotic livers. Since those livers are increasingly used for transplantation, protective strategies must be developed. Reactive oxygen species (ROS) play a key role in hepatic IRI.
Angele, M. K.   +7 more
core   +1 more source

Oxidative stress: new insights on the association of nonalcoholic fatty liver disease and atherosclerosis [PDF]

open access: yes, 2015
Non-alcoholic fatty liver disease (NAFLD) represents the most common and emerging chronic liver disease worldwide. It includes a wide spectrum of liver diseases ranging from simple fatty liver to non-alcoholic steatohepatitis (NASH), which may progress ...
Albanese, Fabiana   +7 more
core   +1 more source

Comparison of the prevalence, severity, and risk factors for hepatic steatosis in HIV-infected and uninfected people

open access: yesBMC Gastroenterology, 2019
Background Hepatic steatosis is prevalent in Western countries, but few studies have evaluated whether the frequency and severity of steatosis are greater in the setting of HIV infection.
Jessie Torgersen   +11 more
doaj   +1 more source

Hepatitis B and concomitant hepatic steatosis [PDF]

open access: yesJournal of Thoracic Disease, 2017
Hepatic steatosis is becoming more common in Asia with prevalence becoming as common as Western countries. Concomitant Hepatitis B and hepatic steatosis is increasingly encountered in clinical practice. The interaction between the two concomitant conditions at both molecular level and clinical outcome remains to be explored. The present review is aimed
Chong Teik, Lim, Rajneesh, Kumar
openaire   +2 more sources

Evaluation of polygenic determinants of non-alcoholic fatty liver disease (NAFLD) by a candidate genes resequencing strategy [PDF]

open access: yes, 2018
NAFLD is a polygenic condition but the individual and cumulative contribution of identified genes remains to be established. To get additional insight into the genetic architecture of NAFLD, GWAS-identified GCKR, PPP1R3B, NCAN, LYPLAL1 and TM6SF2 genes ...
Angelico F   +16 more
core   +1 more source

Association Between Depression and Hepatic Steatosis According to Obese Status: The Korean National Health and Nutrition Examination Survey 2010–2019

open access: yesMedicina
Background and Objectives: Hepatic steatosis is associated with an increased risk of liver-related morbidity and mortality. Although numerous studies have reported associations between depression, obesity, metabolic syndrome, and cardiovascular disease ...
Young Sang Lyu   +3 more
doaj   +1 more source

Subclinical myocardial disease by cardiac magnetic resonance imaging and spectroscopy in healthy HIV/Hepatitis C virus-coinfected persons. [PDF]

open access: yes, 2017
Objective The contribution of hepatitis C virus (HCV) infection to the risk of heart failure in human immunodeficiency virus (HIV)-coinfected persons is unknown.
Ambale-Venkatesh, Bharath   +9 more
core   +2 more sources

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