Results 241 to 250 of about 70,274 (304)

The adiponectin-PPARγ axis in hepatic stellate cells regulates liver fibrosis. [PDF]

Cell Rep
Zhao S, Zhu Q, Lee WH, Funcke JB, Zhang Z, Wang MY, Lin Q, Field B, Sun XN, Li G, Ekane M, Onodera T, Li N, Zhu Y, Kusminski CM, Hinds TD, Scherer PE.   +16 more
europepmc   +1 more source

Multidisciplinary Strategies for Targeting Tumor Dormancy in Breast Cancer Therapeutics: Hallmarks, Mechanism, and Approaches

iMetaMed, EarlyView.
Clinical phases and classification of breast tumor dormancy. Tumor dormancy is described as the period after treatment until residual tumor cells become detectable as relapsing disease in clinic. During the period of clinical tumor dormancy, tumor mass dormancy and cellular dormancy may coexist.
Shu Chen, Hui Chen, Vijaya Raghavan, Jing Huang, Jin Wang   +4 more
wiley   +1 more source

Pro-inflammatory effects of endogenous and recombinant MDA-7/IL-24 with RGD peptide on human hepatic stellate cells. [PDF]

Sci Rep
Daneshparvar A, Hosseini SY, Hamidizadeh N, Jamhiri M, Tanideh N, Sadati MS, Jamhiri I.   +6 more
europepmc   +1 more source

Spatial multi‐omics identifies a NOTCH3‐mediated capillary–mCAF crosstalk driving immune exclusion in hepatocellular carcinoma

iMeta, EarlyView.
Spatial multi‐omics defines a DLL4–NOTCH3–driven capillary–mCAF axis orchestrating fibrotic remodeling and immune exclusion in hepatocellular carcinoma tumor cores, conferring immune checkpoint blockade resistance. Targeting stromal NOTCH3 disrupts this pro‐fibrotic niche, enhances T cell infiltration, and synergizes with anti‐PD‐1 therapy ...
Fansen Ji, Haochen Li, Qi Wang, Xiaojuan Wang, Jiawei Zhang, Ying Xiao, Huan Li, Hao Liu, Tanqing Long, Boyang Wu, Hao Chen, Haoming Xia, Xinquan Liu, Chuanrui Xu, Yibo Gao, Bingjun Tang, Juan Liu, Shizhong Yang, Jiahong Dong   +18 more
wiley   +1 more source

Increased matrix stiffness promotes fibrogenesis of hepatic stellate cells through AP-1-induced chromatin priming. [PDF]

Commun Biol
Zhao W, Yuan W, Dong T, Qi W, Feng Z, Li C, Sun Y.   +6 more
europepmc   +1 more source

Hypervision Proton Surgery: The Future Direction of Proton Therapy

iNew Medicine, EarlyView.
ABSTRACT Proton beams provide unique physical advantages characterized by a low entrance dose, negligible exit dose, and a sharp Bragg peak, which enable superior sparing of normal tissues and support safe dose escalation for improved tumor control. However, conventional photon‐based fractionation remains widely used in proton therapy, where prolonged ...
Li Li, Shuanghu Yuan
wiley   +1 more source

Intercellular communication between hepatic stellate cells and myofibroblasts mediated by osteopontin and FGF18 promotes liver fibrosis. [PDF]

iScience
Seki T, Komazawa-Sakon S, Nishina T, Mikami T, Yagita H, Okunishi K, Tanaka M, Tsuchiya Y, Nakano H.   +8 more
europepmc   +1 more source

Role of PNPLA3 in Hepatic Stellate Cells and Hepatic Cellular Crosstalk. [PDF]

Liver Int
Castanho Martins M, Dixon ED, Lupo G, Claudel T, Trauner M, Rombouts K.   +5 more
europepmc   +1 more source

Hepatic stellate cells control liver zonation, size and functions via R-spondin 3. [PDF]

Nature
Sugimoto A, Saito Y, Wang G, Sun Q, Yin C, Lee KH, Geng Y, Rajbhandari P, Hernandez C, Steffani M, Qie J, Savage T, Goyal DM, Ray KC, Neelakantan TV, Yin D, Melms J, Lehrich BM, Yasaka TM, Liu S, Oertel M, Lan T, Guillot A, Peiseler M, Filliol A, Kanzaki H, Fujiwara N, Ravi S, Izar B, Brosch M, Hampe J, Remotti H, Argemi J, Sun Z, Kendall TJ, Hoshida Y, Tacke F, Fallowfield JA, Blockley-Powell SK, Haeusler RA, Steinman JB, Pajvani UB, Monga SP, Bataller R, Masoodi M, Arpaia N, Lee YA, Stockwell BR, Augustin HG, Schwabe RF.   +49 more
europepmc   +1 more source