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Modulation of hepatic stellate cells and reversibility of hepatic fibrosis

Experimental Cell Research, 2017
Hepatic fibrosis (HF) is the pathological component of a variety of chronic liver diseases. Hepatic stellate cells (HSC) are the main collagen-producing cells in the liver and their activation promotes HF. If HSC activation and proliferation can be inhibited, HF occurrence and development can theoretically be reduced and even reversed.
Yu, Huang, Xin, Deng, Jian, Liang
openaire   +2 more sources

Adipogenic Phenotype of Hepatic Stellate Cells

Alcoholism: Clinical and Experimental Research, 2005
Abstract: Transdifferentiation of hepatic stellate cells (HSC) constitutes a major cellular event in the genesis of alcoholic liver fibrosis and cirrhosis and molecular mechanisms underlying this process is incompletely understood. Our laboratory proposed several years ago that HSC quiescence requires the transcriptional program known to be integral ...
openaire   +2 more sources

P311 modulates hepatic stellate cells migration

Liver International, 2014
AbstractBackground & AimsLiver fibrosis is induced by the accumulation of extracellular matrix, deposited mainly by activated hepatic stellate cells (HSCs). One key characteristic of stellate cell activation is the directional migration to the site of injury during the wound‐healing process.
Stradiot, Leslie   +4 more
openaire   +5 more sources

Hepatic Stellate Cells

2023
Domenico Nicoletti   +2 more
openaire   +2 more sources

Friend or foe? The elusive role of hepatic stellate cells in liver cancer

Nature Reviews Gastroenterology and Hepatology, 2023
Shuang Wang   +2 more
exaly  

Hepatic stellate cells and NK cells in switch from dormancy to liver metastasis

Nature Reviews Gastroenterology and Hepatology, 2021
Jordan Hindson, Hindson Jordan
exaly  

Proteomic Changes of Activated Hepatic Stellate Cells

International Journal of Molecular Sciences, 2021
Michael Trauner   +2 more
exaly  

HEPATIC STELLATE CELLS

Shock, 2004
openaire   +1 more source

Crosstalk between hepatic stellate cells and surrounding cells in hepatic fibrosis

International Immunopharmacology, 2021
Heng Li, Suping Ma
exaly  

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