Results 1 to 10 of about 57,133 (184)
Nature Reviews Gastroenterology & Hepatology, 1996 Autoimmune hepatitis is an inflammatory liver disease in which the immune system is believed to orchestrate an immune attack onto the liver cell. Current knowledge suggests that both T helper 1 (TH1) and TH2 programmes are involved in the generation of the liver damage.
Vergani, D, Mieli-Vergani, G
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Best Practice & Research Clinical Gastroenterology, 2006 Autoimmune hepatitis (AIH) was the first chronic liver disease in which remission was achieved by immunosuppression. Prognosis is poor when left untreated. Since the original description in 1950 by Waldenström, the initially reported treatment option has remained until today and is the core of the basic therapeutic strategy of inducing remission with ...
Michael P. Manns +2 more
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Current Pediatric Reviews, 2015 Autoimmune hepatitis (AIH) is a severe hepatopathy characterised by female preponderance, hypertransaminasaemia, elevated levels of immunoglobulin (IgG), presence of serum autoantibodies and, histologically, by interface hepatitis. AIH occurs both in adults and children, being particularly aggressive in the latter.
Longhi, Maria Serena +2 more
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Pathology of autoimmune hepatitis
Pathologica, 2021 Autoimmune hepatitis (AIH) is a relatively rare non-resolving chronic liver disease, which mainly affects women. It is characterized by hypergammaglobulinemia, circulating autoantibodies, interface hepatitis on liver histology and a favourable response to immunosuppression.
Covelli C. +9 more
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Adolescnet Medicine Clinics, 2004 Autoimmune hepatitis affects all ages with a peak incidence in preadolescent girls. The pathogenesis of autoimmune hepatitis has not been defined. Susceptibility, clinical manifestations, and treatment outcomes are affected by environmental factors, individual immunoregulatory responses, genetic factors, age and gender.
Ding-You, Li, Kathleen B, Schwarz
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Journal of Hepatology, 2011 Autoimmune hepatitis was one of the first liver diseases for which an effective treatment was developed and the benefit proven by randomized controlled trials. Nonetheless, both the diagnosis and the treatment of autoimmune hepatitis remain full of challenges.
Lohse, Ansgar W. +1 more
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Journal of Hepatology, 2000 Autoimmune hepatitis (AIH) is a rare disease, characterized by female predominance, hypergammaglobulinemia, autoantibodies, association with HLA DR3 and HLA DR4 and a good response to immunosuppression. Different subtypes of AIH may be distinguished, based on differences in the autoantibody patterns.
P, Obermayer-Straub +2 more
+7 more sources
Autoimmune Hepatitis and Fibrosis
Journal of Clinical Medicine, 2023 Autoimmune hepatitis (AIH) is a chronic immune-inflammatory disease of the liver, generally considered a rare condition. The clinical manifestation is extremely varied and can range from paucisymptomatic forms to severe hepatitis. Chronic liver damage causes activation of hepatic and inflammatory cells leading to inflammation and oxidative stress ...
Rinaldo Pellicano +5 more
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Pathogenesis of autoimmune hepatitis
World Journal of Hepatology, 2021 Autoimmune hepatitis (AIH) is a chronic progressive liver disease whose etiology and pathogenesis are not yet clear. It is currently believed that the occurrence of AIH is closely related to genetic susceptibility and immune abnormalities, and other factors such as environment, viral infection and drugs that may cause immune dysfunction.
Jun-hua Fan +5 more
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Autoimmune hepatitis: Is the autoimmunity in the family? [PDF]
Liver International, 2018 See Article on Page ...
Marcial Sebode, Ansgar W. Lohse
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