Results 11 to 20 of about 428,885 (246)

Classical autoimmune hepatitis and the IgG4-associated autoimmune hepatitis in paediatric patients

Polish Journal of Pathology
The IgG4-associated autoimmune hepatitis (IgG4-AIH) is a newly proposed disease entity characterised by the accumulation of the IgG4-expressing plasma cells in the liver. Its pathophysiology and clinical significance remain unclear and have poor evidence
Dominika Kaps-Kopiec, Małgorzata Woźniak, Dorota Jarzębicka, Renata Grzywa-Czuba, Joanna Pawłowska, Piotr Czubkowski, Joanna Cielecka-Kuszyk   +6 more
doaj   +2 more sources

Smoking is a Risk Factor for Autoimmune Hepatitis: An English Registry-Based Case–Control Study

Clinical Epidemiology
Lisbet Grønbæk,1– 3 Harmony Omeife,3 Lu Ban,4 Colin J Crooks,5 Timothy R Card,3,4 Peter Jepsen,1,3 Joe West3,4,6 1Department of Hepatology and Gastroenterology, Aarhus University Hospital, Aarhus, Denmark; 2Department of Medicine, Regional Hospital ...
Grønbæk L, Omeife H, Ban L, Crooks CJ, Card TR, Jepsen P, West J   +6 more
doaj   +1 more source

Aminotransferases During Treatment Predict Long-Term Survival in Patients With Autoimmune Hepatitis Type 1:A Landmark Analysis [PDF]

, 2022
Background & Aims: Biochemical remission, important treatment goal in autoimmune hepatitis (AIH), has been associated with better long-term survival.
Sermon, F., van den Berg, Aad, Verhelst, X., Sermon, Filip, Biewenga, M., Drenth, J.P.H., Colle, I., van der Meer, Adriaan, Schouten, J., Dutch Autoimmune Hepatitis Study G, van Hoek, Bart, Hoek, B. van, Meer, A. van der, Meer, Adriaan van der, Steenkiste, C. Van, Baven-Pronk, Martine, Putter, Hein, Putter, H., Vlierberghe, H. van, Berg, A. van den, Colle, Isabelle, Schouten, Jeoffrey, van Vlierberghe, Hans, Van Steenkiste, Christophe, Biewenga, Maaike, Dutch Autoimmune Hepatitis Study Group, Verhelst, Xavier, Baven-Pronk, M.   +27 more
core   +4 more sources

Systematic review of response criteria and endpoints in autoimmune hepatitis by the International Autoimmune Hepatitis Group [PDF]

, 2022
Background & aims: Autoimmune hepatitis (AIH) has been well characterised and codified through the development of diagnostic criteria. These criteria have been adapted and simplified and are widely used in clinical practice.
Montano-Loza, Aldo J, Drenth, Joost P H, Hirschfield, Gideon M, Lenzi, Marco, Schramm, Christoph, Heneghan, Michael A, Dalekos, George N, Levy, Cynthia, Trauner, Michael, International Autoimmune Hepatitis Group (IAIHG), Snijders, Romée J A L M, Gevers, Tom J G, Manns, Michael P, Lohse, Ansgar W, International Autoimmune Hepatitis Group (IAIHG) collaborators(‡), Chazouilleres, Oliver, Pape, Simon, Vierling, John M   +17 more
core   +1 more source

New treatments/targets for primary biliary cholangitis

JHEP Reports, 2019
Summary: Primary biliary cholangitis (PBC) is an autoimmune, cholestatic, chronic liver disease that ultimately progresses towards cirrhosis and liver failure if untreated.
Christophe Corpechot, Raoul Poupon, Olivier Chazouillères   +2 more
doaj   +1 more source

Case Report: Viral Pneumonia Could Prompt the Advancement of Immune-Mediated Liver Disease

Frontiers in Medicine, 2021
Background: The impact of the influenza A (H1N1) and SARS-CoV-2 virus on the development of autoimmune hepatitis has not been described previously.Methods: In this case series, we evaluated the dynamic changes in liver function of three patients with ...
Qian Li, Qian Li, Qian Li, Jun Wang, Jun Wang, Jun Wang, Xueshi Zhou, Hongzhou Lu, Mengji Lu, Lihua Huang   +9 more
doaj   +1 more source

The CYP2D6 animal model: how to induce autoimmune hepatitis in mice [PDF]

, 2012
Autoimmune hepatitis is a rare but life threatening autoimmune disease of the liver of unknown etiology1,2. In the past many attempts have been made to generate an animal model that reflects the characteristics of the human disease 3-5.
Christen, Urs, Hintermann, Edith, Ehser, Janine   +2 more
core   +1 more source

Hepatitis induced by noni juice from Morinda citrifolia: A rare cause of hepatotoxicity or the tip of the iceberg? [PDF]

, 2006
A 24-year-old female patient presented to her community hospital with mild elevations of serum transaminase and bilirubin levels. Because of multiple sclerosis, she was treated with interferon beta-la for 6 weeks.
Yuece, B., Gülberg, Veit, Diebold, J., Gerbes, Alexander L.   +3 more
core   +1 more source

Autoimmune Hepatitis

Gastroenterology Nursing, 2000
Autoimmune hepatitis (AIH) is a necro-inflammatory disease that, untreated, carries a 3-year mortality rate of approximately 50%. In this last of a series of three articles, current knowledge regarding AIH is reviewed. The mode of presentation of AIH is variable: insidious onset with few if any symptoms, presenting with symptoms indistinguishable from ...
P, Obermayer-Straub, C P, Strassburg, M P, Manns   +2 more
  +7 more sources

Breaking tolerance to the natural human liver autoantigen cytochrome P450 2D6 by virus infection [PDF]

, 2008
Autoimmune liver diseases, such as autoimmune hepatitis (AIH) and primary biliary cirrhosis, often have severe consequences for the patient. Because of a lack of appropriate animal models, not much is known about their potential viral etiology. Infection
Hintereder, Gudrun, Gudrun Hintereder, Michael P. Manns, Christen, Urs, Herrath, Matthias G. von, Holdener, Martin, Monika Bayer, Johnson, Eric F., Urs Christen, Rodrigo, Evelyn, Frank J. Gonzalez, Pfeilschifter, Josef (Prof. Dr.), Eric F. Johnson, Evelyn Rodrigo, Gonzalez, Frank J., Martin Holdener, Edith Hintermann, Hintermann, Edith, Matthias von G. Herrath, Josef Pfeilschifter, Rhode, Antje, Bayer, Monika, Manns, Michael P., Antje Rhode   +23 more
core   +1 more source