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Autoimmune hepatitis (AIH) was the first chronic liver disease in which remission was achieved by immunosuppression. Prognosis is poor when left untreated. Since the original description in 1950 by Waldenström, the initially reported treatment option has remained until today and is the core of the basic therapeutic strategy of inducing remission with ...
Stefan, Lueth, Ansgar W, Lohse
+9 more sources
Autoimmune hepatitis (AIH) is a severe hepatopathy characterised by female preponderance, hypertransaminasaemia, elevated levels of immunoglobulin (IgG), presence of serum autoantibodies and, histologically, by interface hepatitis. AIH occurs both in adults and children, being particularly aggressive in the latter.
Longhi, Maria Serena +2 more
openaire +7 more sources
Autoimmune hepatitis is an inflammatory liver disease in which the immune system is believed to orchestrate an immune attack onto the liver cell. Current knowledge suggests that both T helper 1 (TH1) and TH2 programmes are involved in the generation of the liver damage.
Vergani, D, Mieli-Vergani, G
openaire +13 more sources
Liver involvement in pediatric celiac disease [PDF]
Celiac disease (CD) is an intestinal inflammatory disease that manifests in genetically susceptible individuals when exposed to dietary gluten. It is a common chronic disorder, with a prevalence of 1% in Europe and North America.
Anania, Caterina +4 more
core +1 more source
Autoimmune hepatitis (AIH) is a rare disease, characterized by female predominance, hypergammaglobulinemia, autoantibodies, association with HLA DR3 and HLA DR4 and a good response to immunosuppression. Different subtypes of AIH may be distinguished, based on differences in the autoantibody patterns.
P, Obermayer-Straub +2 more
+7 more sources
Case Report: Viral Pneumonia Could Prompt the Advancement of Immune-Mediated Liver Disease
Background: The impact of the influenza A (H1N1) and SARS-CoV-2 virus on the development of autoimmune hepatitis has not been described previously.Methods: In this case series, we evaluated the dynamic changes in liver function of three patients with ...
Qian Li +9 more
doaj +1 more source
Pediatric liver diseases: current challenges and future perspectives [PDF]
Chronic liver diseases in children represent a rising problem with significant effects on public health. In fact, several pediatric liver diseases are precursors of adult chronic hepatopathies, cirrhosis and hepatocellular carcinoma.
Alisi, Anna +5 more
core +1 more source
The communication of a secondary care diagnosis of autoimmune hepatitis to primary care practitioners: a population-based study [PDF]
Background Autoimmune Hepatitis is a chronic liver disease which affects young people and can result in liver failure leading to death or transplantation yet there is a lack of information on the incidence and prevalence of this disease and its natural ...
AD Yeoman +17 more
core +3 more sources
Disease recurrence and rejection following liver transplantation for autoimmune chronic active liver disease [PDF]
Autoimmune chronic active liver disease (ACALD), a major indication for liver transplantation, is associated strongly with antigenic determinants HLA-B8 and DR3.
Block, GD +6 more
core +1 more source
Chronic viral hepatitis is one of the most urgent problems of the healthcare. Viral hepatitis is not restricted with liver damage; they are like systemic disease proceeding with obligate development of extrahepatic manifestations.
Kh.T. Rustamova +2 more
doaj +1 more source

