Results 21 to 30 of about 107,831 (252)

Mitochondrial stress in advanced fibrosis and cirrhosis associated with chronic hepatitis B, chronic hepatitis C, or nonalcoholic steatohepatitis

open access: yesHepatology, EarlyView., 2022
Adaptive mitochondrial mechanisms allow mitochondrial resilience and prevent the worsening of fibrosis, while deregulation of these mechanisms promotes the progression from no/minimal‐mild (F0‐F2) fibrosis to advanced fibrosis and cirrhosis (F3‐F4). Abstract Background and Aims Hepatitis B virus (HBV) infection causes oxidative stress (OS) and alters ...
Dimitri Loureiro   +17 more
wiley   +1 more source

Autoimmune Hepatitis

open access: yesArchives of Pediatric Gastroenterology, Hepatology, and Nutrition, 2022
Autoimmune hepatitis (AIH) is a condition caused by self-perpetuating immune response towards hepatocytes in liver. In children, AIH may progressed more rapidly compared to adults.
Fatima Safira Alatas   +3 more
doaj   +1 more source

Genetic predisposition to porto‐sinusoidal vascular disorder: A functional genomic‐based, multigenerational family study

open access: yesHepatology, EarlyView., 2022
A deleterious variant of FCHSD1 results in mTOR pathway overactivation and may cause porto‐sinusoidal vascular disorder (PSVD). The pedigree of the family demonstrated an autosomal dominant disease with variable expressivity. Whole‐genome sequencing and Sanger sequencing both validated the existence of the FCHSD1 variant and the heterozygosity of c ...
Jingxuan Shan   +19 more
wiley   +1 more source

Health disparities in chronic liver disease

open access: yesHepatology, EarlyView., 2022
Abstract The syndemic of hazardous alcohol consumption, opioid use, and obesity has led to important changes in liver disease epidemiology that have exacerbated health disparities. Health disparities occur when plausibly avoidable health differences are experienced by socially disadvantaged populations.
Ani Kardashian   +3 more
wiley   +1 more source

A Rare Case of Doxycycline-Induced Autoimmune Hepatitis With Organizing Pneumonia

open access: yesAnnals of Internal Medicine: Clinical Cases, 2023
Autoimmune hepatitis and organizing pneumonia are uncommon, yet important, manifestations of drug toxicity. We describe the case of a 67-year-old woman who presented with shortness of breath shortly after completing a course of doxycycline and was ...
Alex R. Jones   +2 more
doaj   +1 more source

Autoimmune hepatitis

open access: yesJournal of Hepatology, 2011
Autoimmune hepatitis was one of the first liver diseases for which an effective treatment was developed and the benefit proven by randomized controlled trials. Nonetheless, both the diagnosis and the treatment of autoimmune hepatitis remain full of challenges.
Lohse, Ansgar W.   +1 more
openaire   +2 more sources

Nicotinamide riboside and pterostilbene reduces markers of hepatic inflammation in NAFLD: A double‐blind, placebo‐controlled clinical trial

open access: yesHepatology, EarlyView., 2022
NRPT 1X reduces ALT and ceramide 14:0 in 65% of subjects as compared to only 28% in the placebo group. Abstract Background and Aims The prevalence of NAFLD is increasing globally and on a path to becoming the most frequent cause of chronic liver disease. Strategies for the prevention and treatment of NAFLD are urgently needed.
Ryan W. Dellinger   +7 more
wiley   +1 more source

Clinical Case of Autoimmune Hepatitis in 59-year-old Woman with Effective Treatment with Budesonide

open access: yesGastroenterologìa, 2013
Autoimmune hepatitis is a necroinflammatory liver disease of unknown etiology. According to the histology the disease is characterized by lobular hepatitis, in blood chemistry — increasing the level of aspartate aminotransferase and alanine ...
L.Ya. Melnychenko   +2 more
doaj   +1 more source

Sjögren’s Syndrome Complicated with Type 2 Autoimmune Hepatitis: A Case Report-Based Review of the Literature

open access: yesEuropean Medical Journal, 2020
This case details a 33-year-old female who presented with a suggestive autoimmune history, arthralgias, and splenomegaly, and tested positive for Sjögren’s syndrome and anti-liver–kidney microsomal antibody.
Muhammad Sohaib Asghar   +5 more
doaj   +1 more source

Autoimmune hepatitis type-2 and Epstein-Barr virus infection in a toddler: art of facts or an artifact?

open access: yesAnnals of Hepatology, 2013
Epstein-Barr virus (EBV) can cause frequently asymptomatic (or anicteric) and self-limited hepatitis, while occasionally may result in considerable cholestatic hepatitis.
Aglaia Zellos   +5 more
doaj   +1 more source

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