Results 141 to 150 of about 104,518 (264)

Viral pathogens in urban rats: A one health systematic review of global surveillance evidence. [PDF]

One Health
Mundt B, Kant R, Grzybek M.
europepmc   +1 more source

Enterovirus infections in children. [PDF]

Pediatr Investig
Enteroviruses (EVs) are major pathogens causing a wide spectrum of diseases in children worldwide. This review summarizes the epidemiology, virology, viral replication, and virus‐host interactions of EVs. It also highlights current advances in clinical diagnosis, antiviral therapies, and vaccine development, providing insights into future strategies ...
Chen X, Guo L, Lei X, Zhao L, Hei M, Shen J, Yin J, Li F, Deng J, Liu G, Zhang Y, Xie Z.   +11 more
europepmc   +2 more sources

Decoding sequence recognition code of nucleic acid‐binding proteins of human‐infecting DNA viruses

iMeta, EarlyView.
Human‐infecting DNA viruses remain major health threats, yet the DNA‐recognition mechanisms of their nucleic acid‐binding proteins (NBPs) are poorly understood. Here, we systematically profiled 103 viral NBPs from human‐infecting DNA viruses, with three NBPs from non‐human‐infecting DNA viruses as controls, using high‐throughput screening.
Meifang Tang, Shifei Yang, Haiqian Ma, Ruoying Guo, Jie Chen, Hui Zhang, Jinghan Zhang, Wei Sun, Yun Wei, Ligang Fan, Jian Yan   +10 more
wiley   +1 more source

Editorial: Cross-species transmission of viral infections. [PDF]

Front Microbiol
Guterres A.
europepmc   +1 more source

Epigenetic Regulation in the Pathogenesis of Renal Inflammation: Insights and Therapeutic Potentials

iNew Medicine, EarlyView.
ABSTRACT Renal inflammation is a common pathological process in various kidney diseases, often initiated by factors such as toxins, ischemia, or autoimmune reactions. This inflammatory response can result in structural damage and a rapid decline in renal function.
Yu‐Hang Dong, Xiao‐Yu Shen, Han‐Cheng Jin, Xiang‐Yu Li, Hao He, Xiao‐Ming Meng   +5 more
wiley   +1 more source

FDA approval of hepcludex: a milestone in the treatment of chronic hepatitis delta virus infection. [PDF]

Ann Med Surg (Lond)
Fatima E, Oduoye MO.
europepmc   +1 more source

The T‐Cell Response Mechanism in Human Papillomavirus‐Associated Cervical Cancer and New Strategies for Immunotherapy

iNew Medicine, EarlyView.
ABSTRACT Human papillomavirus (HPV) is a double‐stranded DNA virus that infects human skin and mucosal tissues exclusively. The German scientist Harald zur Hausen was awarded the 2008 Nobel Prize in Physiology or Medicine for his discovery of the link between HPV infection and cervical cancer.
Fang Zhu, Farah Nazir, Ying Zhou, Yuhua Shang, Hongliang He, Tengchuan Jin   +5 more
wiley   +1 more source

Viral entry defines the hepatitis E virus species barrier in murine hepatocytes. [PDF]

Emerg Microbes Infect
Frericks N, Pinto Veiga O, Sirkinti L, Nguyen HD, Sliwinski T, Guo H, Brüggemann Y, Burkard T, Ulrich RG, Brown RJP, Tuoc T, Nguyen HP, Wang W, Todt D, Kinast V, Steinmann E.   +15 more
europepmc   +1 more source

Tofacitinib Regulates β‐Catenin Nuclear Translocation to Inhibit FLS Migration and Alleviate Clinical Symptoms of RA

iNew Medicine, EarlyView.
ABSTRACT Objective Tofacitinib is a Janus kinase (JAK) inhibitor approved for the treatment of moderate‐to‐severe rheumatoid arthritis (RA). However, its synovium‐related molecular mechanisms, particularly its regulatory effect on fibroblast‐like synoviocyte (FLS) migration, remain incompletely understood.
Shuqi Fang, Tianjing Zhang, Ling Hu, Ruijin Liu, Leyi Jia, Menglin Bai, Jiale Dong, Yuchen Zhao, Han Wang, Lei Zhang, Tao Li, Youcai Deng, Xianzheng Zhang, Lingling Zhang   +13 more
wiley   +1 more source

Mechanisms restricting hepatitis B virus cross-species transmission. [PDF]

mBio
Ijoma JN, Gomez-Moreno A, Ayoub S, Ploss A.   +3 more
europepmc   +1 more source